L-3-n-Butylphthalide Protects HSPB8 K141N Mutation-Induced Oxidative Stress by Modulating the Mitochondrial Apoptotic and Nrf2 Pathways

Inhibitors of Mitochondrial Fission as a Therapeutic Strategy for Diseases with Oxidative Stress and Mitochondrial Dysfunction

(2018) P. Hemachandra Reddy   JOURNAL OF ALZHEIMERS DISEASE

Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity

(2016) A.M. Bertholet et al.   NEUROBIOLOGY OF DISEASE

Mechanisms of apoptosis

(2015) M. A. Savitskaya et al.   BIOCHEMISTRY-MOSCOW

Mitochondrial fission and fusion

(2015) M. V. Patrushev et al.   BIOCHEMISTRY-MOSCOW

The role of mitochondrial dysfunction in age-related diseases

(2015) Rebecca K. Lane et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis

(2015) Margit Fuchs et al.   PLoS Genetics

Mitochondria-controlled signaling mechanisms of brain protection in hypoxia

(2015) Ludmila D. Lukyanova et al.   Frontiers in Neuroscience

Saikosaponin-D Attenuates Heat Stress-Induced Oxidative Damage in LLC-PK1 Cells by Increasing the Expression of Anti-Oxidant Enzymes and HSP72

(2014) Bao-Zhen Zhang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

The Centrality of Mitochondria in the Pathogenesis and Treatment of Parkinson's Disease

(2014) Angelique Camilleri et al.   CNS Neuroscience & Therapeutics

A novel Lys141Thr mutation in small heat shock protein 22 (HSPB8) gene in Charcot–Marie–Tooth disease type 2L

(2013) Khriezhanuo Nakhro et al.   NEUROMUSCULAR DISORDERS

A Nonsense Mutation in DHTKD1 Causes Charcot-Marie-Tooth Disease Type 2 in a Large Chinese Pedigree

(2012) Wang-yang Xu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mitofusin2 Mutations Disrupt Axonal Mitochondrial Positioning and Promote Axon Degeneration

(2012) A. L. Misko et al.   JOURNAL OF NEUROSCIENCE

Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients

(2012) Joy Irobi et al.   NEUROMUSCULAR DISORDERS

l-3-n-butylphthalide improves cognitive deficits in rats with chronic cerebral ischemia

(2012) Jing Xu et al.   NEUROPHARMACOLOGY

Small Heat-Shock Protein HSPB1 Mutants Stabilize Microtubules in Charcot-Marie-Tooth Neuropathy

(2011) L. Almeida-Souza et al.   JOURNAL OF NEUROSCIENCE

Dl-3-n-butylphthalide, a natural antioxidant, protects dopamine neurons in rotenone models for Parkinson's disease

(2011) Nian Xiong et al.   NEUROBIOLOGY OF AGING

(S)-ZJM-289, a nitric oxide-releasing derivative of 3-n-butylphthalide, protects against ischemic neuronal injury by attenuating mitochondrial dysfunction and associated cell death

(2011) Qian Zhao et al.   NEUROCHEMISTRY INTERNATIONAL

Protective effect of 3-butyl-6-bromo-1(3H)-isobenzofuranone on hydrogen peroxide-induced damage in PC12 cells

(2010) Yuan Gao et al.   BRAIN RESEARCH

Mutant HSPB8 causes motor neuron-specific neurite degeneration

(2010) Joy Irobi et al.   HUMAN MOLECULAR GENETICS

dl-3-n-Butylphthalide prevents oxidative damage and reduces mitochondrial dysfunction in an MPP+-induced cellular model of Parkinson's disease

(2010) Jin-zhong Huang et al.   NEUROSCIENCE LETTERS

Enhanced angiogenesis with dl-3n-butylphthalide treatment after focal cerebral ischemia in RHRSP

(2009) Song-Jie Liao et al.   BRAIN RESEARCH

dl-3-n-butylphthalide protects endothelial cells against oxidative/nitrosative stress, mitochondrial damage and subsequent cell death after oxygen glucose deprivation in vitro

(2009) Ling Li et al.   BRAIN RESEARCH

Charcot–Marie–Tooth disease

(2009) Kinga Szigeti et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Long-term treatment of l-3-n-butylphthalide attenuated neurodegenerative changes in aged rats

(2009) Shiping Ma et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Histopathological Findings in Hereditary Motor and Sensory Neuropathy of Axonal Type With Onset in Early Childhood Associated WithMitofusin 2Mutations

(2008) Jean-Michel Vallat et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Endogenous neuroprotection: Mitochondria as gateways to cerebral preconditioning?

(2008) Ulrich Dirnagl et al.   NEUROPHARMACOLOGY

Structure, properties, and functions of the human small heat-shock protein HSP22 (HspB8, H11, E2IG1): A critical review

(2007) Anton A. Shemetov et al.   JOURNAL OF NEUROSCIENCE RESEARCH