Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis

Treatment with abatacept prevents experimental dermal fibrosis and induces regression of established inflammation-driven fibrosis

(2016) Matthieu Ponsoye et al.   ANNALS OF THE RHEUMATIC DISEASES

OX40L blockade protects against inflammation-driven fibrosis

(2016) Muriel Elhai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of an Association ofTNFAIP3Polymorphisms With Matrix Metalloproteinase Expression in Fibroblasts in an Integrative Study of Systemic Sclerosis-Associated Genetic and Environmental Factors

(2016) Peng Wei et al.   Arthritis & Rheumatology

Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients

(2015) Julia Hoffmann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex

(2015) Morane Le Hiress et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

New Molecular Targets of Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension

(2015) Christophe Guignabert et al.   CHEST

Leptin signalling system as a target for pulmonary arterial hypertension therapy

(2015) Alice Huertas et al.   EUROPEAN RESPIRATORY JOURNAL

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

(2015) Nazzareno Galiè et al.   EUROPEAN RESPIRATORY JOURNAL

Predictive Value of Serial High-Resolution Computed Tomography Analyses and Concurrent Lung Function Tests in Systemic Sclerosis

(2015) Anna-Maria Hoffmann-Vold et al.   Arthritis & Rheumatology

Immune Dysregulation and Endothelial Dysfunction in Pulmonary Arterial Hypertension

(2014) Alice Huertas et al.   CIRCULATION

Advances in Therapeutic Interventions for Patients With Pulmonary Arterial Hypertension

(2014) Marc Humbert et al.   CIRCULATION

Increased Pericyte Coverage Mediated by Endothelial-Derived Fibroblast Growth Factor-2 and Interleukin-6 Is a Source of Smooth Muscle–Like Cells in Pulmonary Hypertension

(2014) Nicolas Ricard et al.   CIRCULATION

Performance of the 2013 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Systemic Sclerosis (SSc) in Large, Well-defined Cohorts of SSc and Mixed Connective Tissue Disease

(2014) A.-M. Hoffmann-Vold et al.   JOURNAL OF RHEUMATOLOGY

Progenitor Cells in Pulmonary Vascular Remodeling

(2014) Michael E. Yeager et al.   Pulmonary Circulation

Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension

(2013) Rubin M. Tuder et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects

(2012) Jose Gomez-Arroyo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis

(2012) Jérôme Avouac et al.   ANNALS OF THE RHEUMATIC DISEASES

Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis

(2012) Britta Maurer et al.   ANNALS OF THE RHEUMATIC DISEASES

Matrix metalloproteinases and their inhibitors in pulmonary hypertension

(2012) Prakash Chelladurai et al.   EUROPEAN RESPIRATORY JOURNAL

Targeting PDGF pathway in pulmonary arterial hypertension

(2012) Sabina Antonela Antoniu   EXPERT OPINION ON THERAPEUTIC TARGETS

Matrix Metalloproteinase-10 (MMP-10) Interaction with Tissue Inhibitors of Metalloproteinases TIMP-1 and TIMP-2

(2012) Jyotica Batra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C-Kit–Positive Cells Accumulate in Remodeled Vessels of Idiopathic Pulmonary Arterial Hypertension

(2011) David Montani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Insights into the pathogenesis of systemic sclerosis based on the gene expression profile of progenitor-derived endothelial cells

(2011) Jérôme Avouac et al.   ARTHRITIS AND RHEUMATISM

Platelet-derived growth factor receptor-β and epidermal growth factor receptor in pulmonary vasculature of systemic sclerosis-associated pulmonary arterial hypertension versus idiopathic pulmonary arterial hypertension and pulmonary veno-occlusive disease: a case-control study

(2011) Maria J Overbeek et al.   ARTHRITIS RESEARCH & THERAPY

Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

(2010) A. J. Tyndall et al.   ANNALS OF THE RHEUMATIC DISEASES

Survival in Patients With Idiopathic, Familial, and Anorexigen-Associated Pulmonary Arterial Hypertension in the Modern Management Era

(2010) Marc Humbert et al.   CIRCULATION

Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension

(2010) M. Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

Expression profiling of ETS and MMP factors in VEGF-activated endothelial cells: Role of MMP-10 in VEGF-induced angiogenesis

(2010) Sun-Hee Heo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Prevalence of Pulmonary Hypertension in Systemic Sclerosis in European Caucasians and Metaanalysis of 5 Studies

(2010) J. AVOUAC et al.   JOURNAL OF RHEUMATOLOGY

Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization

(2009) C. Guignabert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Evidence of Dysfunction of Endothelial Progenitors in Pulmonary Arterial Hypertension

(2009) Mark Toshner et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Transcription Factor Fos-Related Antigen-2 Induces Progressive Peripheral Vasculopathy in Mice Closely Resembling Human Systemic Sclerosis

(2009) Britta Maurer et al.   CIRCULATION

BMP Signaling Induces Cell-Type-Specific Changes in Gene Expression Programs of Human Keratinocytes and Fibroblasts

(2009) Michael Y. Fessing et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Circulating endothelial progenitor cells in systemic sclerosis: association with disease severity

(2008) J Avouac et al.   ANNALS OF THE RHEUMATIC DISEASES

Angiogenesis in systemic sclerosis: Impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor-derived cells under hypoxic conditions

(2008) J. Avouac et al.   ARTHRITIS AND RHEUMATISM

Strikingly Different Angiogenic Properties of Endothelial Progenitor Cell Subpopulations

(2008) Daniel P. Sieveking et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Identification of candidate genes in scleroderma-related pulmonary arterial hypertension

(2008) Dmitry N. Grigoryev et al.   Translational Research