Lupus-Associated Functional Polymorphism in PNP Causes Cell Cycle Abnormalities and Interferon Pathway Activation in Human Immune Cells

Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus

(2014) S N Kariuki et al.   GENES AND IMMUNITY

Cutting Edge: Autoimmune Disease Risk Variant of STAT4 Confers Increased Sensitivity to IFN-  in Lupus Patients In Vivo

(2014) S. N. Kariuki et al.   JOURNAL OF IMMUNOLOGY

Constitutive Type I Interferon Modulates Homeostatic Balance through Tonic Signaling

(2012) Daniel J. Gough et al.   IMMUNITY

IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus

(2011) Timothy B Niewold et al.   ANNALS OF THE RHEUMATIC DISEASES

Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

(2011) Nicolas Chevrier et al.   CELL

A novel mutation in purine nucleoside phosphorylase in a child with normal uric acid levels

(2009) B. Al-Saud et al.   CLINICAL BIOCHEMISTRY

Polo-like kinases: conservation and divergence in their functions and regulation

(2009) Vincent Archambault et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses

(2009) I. Amit et al.   SCIENCE

Age‐ and sex‐related patterns of serum interferon‐α activity in lupus families

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Serum type I interferon activity is dependent on maternal diagnosis in anti-SSA/Ro–positive mothers of children with neonatal lupus

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history

(2008) P FITZGERALDBOCARSLY et al.   CYTOKINE & GROWTH FACTOR REVIEWS