期刊
NEURAL PLASTICITY
卷 2017, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2017/9297621
关键词
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资金
- National Natural Science Foundation of China [81601563, 81271549, 81470816, 61431013, 81501543, 81571753]
- National Institute on Alcoholism and Alcohol Abuse of the United States [Z01AA3009]
- National Natural Science Foundation of China [81601563, 81271549, 81470816, 61431013, 81501543, 81571753]
- National Institute on Alcoholism and Alcohol Abuse of the United States [Z01AA3009]
Negative urgency (NU) and positive urgency (PU) are implicated in several high-risk behaviors, such as eating disorders, substance use disorders, and nonsuicidal self-injury behavior. The current study aimed to explore the possible link between trait of urgency and brain activity at rest. We assessed the amplitude of low-frequency fluctuations (ALFF) of the resting-state functional magnetic resonance imaging (fMRI) signal in 85 healthy volunteers. Trait urgency measures were related to ALFF in the lateral orbitofrontal cortex, dorsolateral prefrontal cortex, ventral and dorsal medial frontal cortex, anterior cingulate, and posterior cingulate cortex/precuneus. In addition, trait urgency measures showed significant correlations with the functional connectivity of the posterior cingulate cortex/precuneus seed with the thalamus and midbrain region. These findings suggest an association between intrinsic brain activity and impulsive behaviors in healthy humans.
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