Article
Cardiac & Cardiovascular Systems
Stefano Figliozzi, Antonia Camporeale, Sara Boveri, Federico Pieruzzi, Maurizio Pieroni, Paola Lusardi, Marco Spada, Renzo Mignani, Alessandro Burlina, Francesca Graziani, Silvia Pica, Lara Tondi, Andrea Bernardini, Kelvin Chow, Mehdi Namdar, Massimo Lombardi
Summary: The study developed an ECG-based nomogram to accurately estimate the probability of detecting low T1 values on CMR in FD patients. The nomogram, incorporating parameters such as Sokolow-Lyon index, Pwave/PRsegment ratio, QRS duration, and QT duration, accurately identified CMR patients with evidence of glycosphingolipid storage.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Review
Medicine, General & Internal
George Markousis-Mavrogenis, Aikaterini Giannakopoulou, Antonios Belegrinos, Maria Roser Pons, Maria Bonou, Vasiliki Vartela, Antigoni Papavasiliou, Aikaterini Christidi, Soultana Kourtidou, Genovefa Kolovou, Flora Bacopoulou, George P. Chrousos, Sophie I. Mavrogeni
Summary: Rare cardiovascular diseases have low incidence but significant clinical impact. Cardiovascular Magnetic Resonance is useful for the diagnosis and management of these diseases, providing various types of information in one examination.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Health Care Sciences & Services
Sophie I. I. Mavrogeni, George Markousis-Mavrogenis, Flora Bacopoulou, George P. P. Chrousos
Summary: Diabetes mellitus is a growing epidemic associated with an increase in obesity, causing cardiovascular disease and reducing life expectancy. While strict glycemic control is proven effective for type 1 diabetes, its role in type 2 diabetes remains unclear. Therefore, multifactorial risk reduction is the most efficient prevention strategy.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Robert J. Holtackers, Joachim E. Wildberger, Bernd J. Wintersperger, Amedeo Chiribiri
Summary: Cardiac magnetic resonance imaging (MRI) is commonly used for noninvasive assessment of cardiac structure and function, with 1.5 T traditionally being the preferred field strength. While 3 T systems have seen significant growth in the past decade, there are still challenges hindering their widespread clinical use for cardiac applications. Different clinical benefits exist for each field strength and there is no universal recommendation for the ideal field strength for cardiac MRI. The review discusses the physical differences between 1.5 and 3 T, their impact on various cardiac MRI applications, and provides solutions to overcome potential limitations.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Maan Malahfji, Valentina Crudo, Yodying Kaolawanich, Duc T. Nguyen, Amr Telmesani, Mujtaba Saeed, Michael J. Reardon, William A. Zoghbi, Venkateshwar Polsani, Michael Elliott, Robert O. Bonow, Edward A. Graviss, Raymond Kim, Dipan J. Shah
Summary: This study evaluated the association of cardiac magnetic resonance (CMR) findings with outcomes in aortic regurgitation (AR) patients. The study found that left ventricular end-systolic volume (LVES) ≥ 43 mL/m2 and indexed left ventricular end-diastolic volume ≥ 109 mL/m2 were independently associated with outcomes. CMR can be used to guide management in asymptomatic AR patients with preserved left ventricular ejection fraction (LVEF).
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jimin Lee, Ki Seok Choo, Yeon Joo Jeong, Geewon Lee, Minhee Hwang, Maria Roselle Abraham, Ji Won Lee
Summary: This study aimed to evaluate whether cardiovascular magnetic resonance (CMR)-derived parameters of left atrial strain can predict outcomes in patients with acute myocarditis. The study found that CMR-derived left atrial reservoir and conduit strains are independent predictors of adverse clinical outcomes in patients with acute myocarditis.
KOREAN JOURNAL OF RADIOLOGY
(2023)
Article
Sport Sciences
M. Frenken, C. Schleich, K. L. Radke, A. Mueller-Lutz, C. Benedikter, A. Franz, G. Antoch, B. Bittersohl, D. B. Abrar, S. Nebelung
Summary: This study used compositional Magnetic Resonance Imaging (MRI) to assess the changes in lumbar intervertebral discs (IVDs) in elite athletes and age-matched controls as a result of long-term training. The results showed that professional rowing was associated with increased glycosaminoglycan (GAG) content and strong remodeling effects in the lumbar IVDs. Core-strengthening full-body exercise, apart from rowing, may help enhance the resilience of the lumbar spine and potentially serve as a therapeutic target for treating back pain.
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2022)
Article
Cardiac & Cardiovascular Systems
Jacqueline Chua, Thu-Thao Le, Yin Ci Sim, Hui Yi Chye, Bingyao Tan, Xinwen Yao, Damon Wong, Briana W. Y. Ang, Desiree-Faye Toh, Huishan Lim, Jennifer A. Bryant, Tien Yin Wong, Calvin Woon Loong Chin, Leopold Schmetterer
Summary: This study found significant correlations between retinal capillary density and markers of adverse cardiac remodeling in patients with hypertension, highlighting the potential of optical coherence tomography angiography as a non-invasive index for vascular risk stratification in individuals with hypertension.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Review
Medicine, General & Internal
Xiaoting Wei, Ling Lin, Guizhi Zhang, Xuhui Zhou
Summary: This review focuses on the application of cardiovascular magnetic resonance (CMR) techniques in the early detection of myocardial injury caused by cancer therapies. The existing studies and ongoing clinical trials using CMR for assessing subclinical ventricular dysfunction and myocardial changes are summarized. Continuous non-invasive monitoring of myocardial toxicity associated with cancer therapy has the potential to improve the survival rate of cancer patients.
Article
Computer Science, Interdisciplinary Applications
Elisabeth Hoppe, Jens Wetzl, Seung Su Yoon, Mario Bacher, Philipp Roser, Bernhard Stimpel, Alexander Preuhs, Andreas Maier
Summary: The study presents a sensor-free, deep learning-based navigation method for continuous cardiac MRI scans, which accurately estimates R-wave timepoints without the need for prior knowledge, eliminating the additional workflow associated with traditional ECG navigation. The approach achieves high accuracy and comparable image quality to ECG-based reconstruction methods.
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2021)
Review
Nutrition & Dietetics
Sophie Mavrogeni, Flora Bacopoulou, George Markousis-Mavrogenis, George Chrousos, Evangelia Charmandari
Summary: Obesity is a major public health challenge, contributing to approximately 5% of global deaths, primarily due to cardiovascular disease. Cardiovascular noninvasive imaging offers early and accurate information for obese individuals, but traditional techniques have limitations in this population.
Article
Biophysics
Yingying Zhang, Siwen Liu, Danyan Li, Chunyan He, Dongxu Wang, Min Wei, Shaohui Zheng, Jingjing Li
Summary: This study proposes the use of nano-sized ferroferric oxide/single wall carbon nanotubes composites (Fe3O4-SWCNT) to engineer macrophages for cancer therapy. The engineered macrophages can effectively promote the polarization of endogenous M2-like macrophages to M1-like macrophages, activate tumor immune response, and inhibit tumor progression.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Review
Cardiac & Cardiovascular Systems
Tomaz Podlesnikar, Bostjan Berlot, Jure Dolenc, Katja Goricar, Tanja Marinko
Summary: Radiotherapy is an important cancer therapy, but it can cause cardiac injury. Multimodality cardiac imaging is useful for detecting and monitoring this injury. Serum biomarkers and genetic polymorphisms are also associated with the risk of cardiovascular disease and can be used for comprehensive screening of cardiotoxicity.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Maciej Haberka, Mariusz Balys, Zbigniew Gasior, Bartlomiej Stasiow
Summary: This study compared TTE and CMR measurements in grading aortic regurgitation and left ventricle remodeling. The results showed that CMR provided a more comprehensive assessment with weak to moderate agreement compared to TTE.
KARDIOLOGIA POLSKA
(2021)
Article
Oncology
Benjamin Buck, Aaron P. P. Chum, Mitkumar Patel, Rebecca Carter, Haseeb Nawaz, Vedat Yildiz, Patrick Ruz, Tracy Wiczer, Kerry A. A. Rogers, Farrukh T. T. Awan, Seema Bhat, Avirup Guha, Adam S. S. Kittai, Orlando P. P. Simonetti, Subha V. V. Raman, Grant Wallace, Reynaldo Sanchez, Janice M. M. Bonsu, John Gambril, Devin Haddad, James Mann, Lai Wei, Onaopepo Kola-Kehinde, John C. C. Byrd, Jennifer A. A. Woyach, Daniel Addison
Summary: Myocardial injury is common in patients treated with ibrutinib and is associated with higher cardiotoxic risk. Cardiovascular magnetic resonance can be used to assess the occurrence and outcomes of ibrutinib-related cardiotoxicity.
Article
Radiology, Nuclear Medicine & Medical Imaging
Theo Pezel, Bharath Ambale-Venkatesh, Thiago Quinaglia, Susan R. Heckbert, Yoko Kato, Henrique Doria de Vasconcellos, Colin O. Wu, Wendy S. Post, Patrick Henry, David A. Bluemke, Joao A. C. Lima
Summary: The left atrioventricular coupling index and its change can serve as independent predictors of atrial fibrillation, providing valuable prognostic information.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Chikara Noda, Bharath Ambale Venkatesh, Jennifer D. Wagner, Yoko Kato, Jason M. Ortman, Joao A. C. Lima
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Prashant Nagpal, David A. Bluemke
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
David A. Bluemke
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
David A. Bluemke
Article
Cardiac & Cardiovascular Systems
Francesco Bianco, Raffaele De Caterina, Alvin Chandra, Iolanda Aquila, Brian Claggett, Michelle C. Johansen, Alexandra Goncalves, Faye L. Norby, Rebecca Cogswell, Elsayed Z. Soliman, Rebecca Gottesman, Thomas Mosley, Alvaro Alonso, Amil Shah, Scott D. Solomon, Lin Yee Chen
Summary: The study found that age-related left atrial structural and functional abnormalities are associated with subclinical cerebral infarcts (SCIs) and stroke in elderly patients. The deterioration of LA global longitudinal strain and E/e' divided by LA global longitudinal strain is related to age increment and increased odds of SCIs and stroke.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Bharath Ambale-Venkatesh, Joao A. C. Lima
Article
Neurosciences
Naga Venkata K. Pothineni, Elsayed Z. Soliman, Mary Cushman, George Howard, Virginia J. Howard, Scott E. Kasner, Suzanne Judd, J. David Rhodes, Francis E. Marchlinski, Rajat Deo
Summary: This study examined the feasibility of telephone guided, mail-in ambulatory long-term cardiac rhythm monitoring in Black and White stroke survivors, and found a high prevalence of arrhythmias among those who completed monitoring.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Charlene A. Mauger, Kathleen Gilbert, Avan Suinesiaputra, David A. Bluemke, Colin O. Wu, Joao A. C. Lima, Alistair A. Young, Bharath Ambale-Venkatesh
Summary: This study aimed to quantify the relationship between left ventricular (LV) three-dimensional shape at MRI and incident cardiovascular events over 10 years. Results showed that adding LV remodeling signatures to traditional cardiovascular risk factors improved the prediction of heart failure, coronary heart disease, and cardiovascular disease events over 10 years.
Article
Cardiac & Cardiovascular Systems
Maria Doughan, Omar Chehab, Henrique Doria de Vasconcellos, Ralph Zeitoun, Vinithra Varadarajan, Bassel Doughan, Colin O. Wu, Michael J. Blaha, David A. Bluemke, Joao A. C. Lima
Summary: A self-reported history of periodontal disease was found to be associated with increased measures of interstitial myocardial fibrosis in men, but not in women. This suggests a possible link between periodontal disease and subclinical myocardial fibrosis.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Letter
Cardiac & Cardiovascular Systems
Emilie K. Frimodt-Moller, John S. Gottdiener, Elsayed Z. Soliman, Jorge R. Kizer, Eric Vittinghoff, Bruce M. Psaty, Tor Biering-Sorensen, Gregory M. Marcus
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Muhammad Imtiaz Ahmad, Mai Z. Soliman, Elsayed Z. Soliman
Summary: The presence of premature ventricular complexes (PVCs) is associated with an increased risk of stroke mortality, particularly in individuals with coronary heart disease (CHD). Prospective studies are needed to investigate whether improved hospital care or modification of PVCs could improve outcomes.
JOURNAL OF ELECTROCARDIOLOGY
(2023)
Article
Nutrition & Dietetics
Linzi Li, Pamela L. Lutsey, Lin Yee Chen, Elsayed Z. Soliman, Mary R. Rooney, Alvaro Alonso
Summary: Higher serum magnesium is associated with a lower risk of cardiovascular events, especially myocardial infarction, in patients with atrial fibrillation.
Article
Urology & Nephrology
Faeq Husain-Syed, Matthew F. DiFrancesco, Rajat Deo, R. Graham Barr, Julia J. Scialla, David A. Bluemke, Richard A. Kronmal, Joao A. C. Lima, Amy Praestgaard, Russell P. Tracy, Michael Shlipak, Steven M. Kawut, John S. Kim
Summary: Low glomerular filtration rate (GFR) and increased albuminuria are associated with all-cause and cardiovascular mortality. Limited data are available on the independent associations of GFR and albuminuria with cardiac morphology, especially in early chronic kidney disease (CKD). This study found that reductions in eGFR within the normal range and higher albuminuria were associated with smaller right ventricular volumes, and albuminuria had a stronger association with mortality among those with smaller RV volumes.
CLINICAL KIDNEY JOURNAL
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tarek Zghaib, Thiago Quinaglia A. C. Silva, Bharath Ambale-Venkatesh, Eric Xie, Mohammad R. Ostovaneh, Mohammadali Habibi, David A. Bluemke, Elsayed Z. Soliman, Colin O. Wu, Susan R. Heckbert, Saman Nazarian, Joao A. C. Lima
Summary: The purpose of this study was to investigate the prevalence and correlates of left atrial late gadolinium enhancement (LGE) at cardiac MRI and its association with atrial fibrillation (AF). The results showed that LA LGE was associated with adverse atrial remodeling and independently predicted the development of AF in a multiethnic population-based sample.
RADIOLOGY-CARDIOTHORACIC IMAGING
(2023)