Article
Biology
Lucas M. Walker, James R. J. Haycocks, Julia C. Van Kessel, Triana N. Dalia, Ankur B. Dalia, David C. Grainger
Summary: Many bacteria use quorum sensing to control changes in lifestyle. In Vibrio cholerae, quorum-sensing signals are transduced to the transcription factor LuxO. HapR targets 32 loci and overlaps with sites for the cAMP receptor protein (CRP), allowing integration of quorum sensing and cAMP signaling to control gene expression.
Article
Fisheries
Yibin Yang, Haixin Zhang, Yongtao Liu, Jing Dong, Ning Xu, Qiuhong Yang, Shun Zhou, Xiaohui Ai
Summary: Bluegill sunfish is an important economic fish, but a fatal bacterial disease has been occurring in recent years. This study isolated and identified Vibrio cholerae from diseased bluegill sunfish for the first time, providing a basis for the diagnosis, prevention, and treatment of the disease.
AQUACULTURE REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Andrew A. Bridges, Jojo A. Prentice, Chenyi Fei, Ned S. Wingreen, Bonnie L. Bassler
Summary: This study quantitatively captures the mechanism by which bacteria use cyclic diguanylate (c-di-GMP) to transduce sensory information and regulate gene expression in biofilms. It shows that the bifunctional polyamine receptor NspS-MbaA enables local signaling and sensitivity to polyamines, which in turn regulates biofilm formation.
Review
Microbiology
Laura Alvarez, Sara B. Hernandez, Felipe Cava
Summary: The cell wall of most bacteria, composed of peptidoglycan, plays a crucial role in protecting them from environmental stressors. Vibrio cholerae has become a major model for studying cell wall genetic determinants, regulatory links, and adaptive mechanisms, shedding light on novel insights. This review provides a comprehensive overview of V. cholerae's cell wall biology and genetics, emphasizing the similarities and differences with Escherichia coli.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 75, 2021
(2021)
Article
Microbiology
Heidi A. Butz, Alexandra R. Mey, Ashley L. Ciosek, Alexander A. Crofts, Bryan W. Davies, Shelley M. Payne
Summary: CsrA is a critical posttranscriptional global regulator in Vibrio cholerae, controlling 22% of the bacterial transcriptome involving various cellular processes. Through RNA coimmunoprecipitation experiments, it was found that CsrA binds to multiple mRNAs encoding regulatory proteins, including major sigma factors. Additionally, CsrA directly binds to virulence gene transcripts, positively regulating the production of important virulence factors.
Article
Biochemistry & Molecular Biology
Rotem Sela, Brian K. Hammer, Malka Halpern
Summary: The study found that interactions between Vibrio cholerae and chironomid egg mass microbiota can affect HAP production and egg mass degradation activities, potentially providing insights into the interactions between this pathogen and human gut microbiota.
Article
Biochemistry & Molecular Biology
Junxiang Yan, Qian Liu, Xinke Xue, Jinghao Li, Yuehua Li, Yingying Su, Boyang Cao
Summary: This study reveals that the VC1795 gene plays a key role in the intestinal colonization and pathogenicity of Vibrio cholerae, and it regulates the expression of its downstream gene, VC1794, and the toxin-coregulated pilus (TCP) cluster. These findings provide insights into the regulatory mechanisms of VC1795 in bacterial pathogenesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Milena Jaskolska, David W. Adams, Melanie Blokesch
Summary: Horizontal gene transfer is a key driver of bacterial evolution, facilitated by mobile genetic elements such as plasmids and bacteriophages. This study identifies two conserved plasmid defence systems in Vibrio cholerae, responsible for the ongoing cholera pandemic. These systems rapidly eliminate small plasmids and defend against bacteriophage infection. Additionally, they increase the burden of large conjugative plasmids, leading to a fitness disadvantage for plasmid-carrying cells. These findings explain the rarity of plasmids in pandemic strains and have implications for understanding antibiotic resistance plasmid dissemination and the evolution of pandemic V. cholerae.
Article
Biochemistry & Molecular Biology
Claire Vit, Egill Richard, Florian Fournes, Clemence Whiteway, Xavier Eyer, Delphine Lapaillerie, Vincent Parissi, Didier Mazel, Celine Loot
Summary: In this study, it was found that cassette recruitment in the Vibrio cholerae chromosomal integron mainly occurs at the attIA site, with newly inserted cassettes being expressed and selected due to the presence of a promoter in the vicinity of this site. The RecA protein plays a critical role in this process, but the V. cholerae integron integrase is not active in other bacteria.
NUCLEIC ACIDS RESEARCH
(2021)
Article
Microbiology
Benjamin Kostiuk, Mark E. Becker, Candice N. Churaman, Joshua J. Black, Shelley M. Payne, Stefan Pukatzki, Benjamin J. Koestler
Summary: Vibrio cholerae competes with other bacteria by metabolizing diverse carbon sources, resulting in the creation of an alkaline environment that inhibits the growth of other Gram-negative bacteria.
MICROBIOLOGY SPECTRUM
(2023)
Article
Immunology
Wilfredo R. Matias, Yodeline Guillaume, Gertrude Cene Augustin, Kenia Vissieres, Ralph Ternier, Richelle C. Charles, Jason B. Harris, Molly F. Franke, Louise C. Ivers
Summary: In 2017, the prevalence of cholera infection was high among adults in two areas of Haiti, indicating the need for improved surveillance programs to guide public health interventions.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Environmental Sciences
Candice A. Thorstenson, Matthias S. Ullrich
Summary: The potential spread of infectious diseases in response to climate change and rising sea surface temperatures in temperate regions has raised concerns over the past few decades. Different species of Vibrio, particularly Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio vulnificus, have been correlated with human health risks in relation to extreme heat waves in the North Atlantic and North Sea regions. Studying the behavior and ecology of both pathogenic and non-pathogenic strains of these bacteria can provide insights into their native microbiome and how they disperse in coastal regions.
FRONTIERS IN MARINE SCIENCE
(2021)
Article
Multidisciplinary Sciences
Jiandong Chen, Hyuntae Byun, Rui Liu, I-Ji Jung, Qinqin Pu, Clara Y. Zhu, Ethan Tanchoco, Salma Alavi, Patrick H. Degnan, Amy T. Ma, Manuela Roggiani, Joris Beld, Mark Goulian, Ansel Hsiao, Jun Zhu
Summary: The genotoxin colibactin produced by commensal Escherichia coli can not only induce DNA damage in host intestinal cells, but also target a variety of enteric pathogens and commensals via a contact-dependent mechanism. Furthermore, colibactin can shape the microbiome by species-specific targeting of Bacteroides fragilis, a common gut-associated microbe.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Microbiology
Lori M. M. Gladney, Taylor Griswold, Maryann Turnsek, Monica S. S. Im, Michele M. B. Parsons, Lee S. S. Katz, Cheryl L. L. Tarr, Christine C. C. Lee
Summary: The rise in vibriosis cases and the importance of surveillance of toxigenic Vibrio cholerae strains are emphasized due to climate events and ocean warming. Traditional phenotyping using antisera against O1 and O139 is limited for non-O1/non-O139 strains. Whole-genome sequencing analysis and phylogenetic methods were used to investigate a nonagglutinating strain and its relationship to other strains recovered from vibriosis cases.
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Lipika Das, Sushanta Deb, Eiji Arakawa, Shinji Yamasaki, Subrata K. Das
Summary: This study describes the genomic characteristics of Vibrio cholerae strain PS-4, which is unable to ferment sucrose on TCBS agar due to the absence of the sucrose-specific phosphotransferase system IIB gene (sucR). The findings indicate niche-specific adaptive evolution for strain PS-4, which shows distinct metabolic pathways and genomic features compared to other V. cholerae strains.
MICROBIOLOGY SPECTRUM
(2022)
Review
Obstetrics & Gynecology
Manal Massalha, Ido Izhaki, Rula Iskander, Raed Salim
Summary: This study examined the effect of inhaled nitrous oxide on the success rate and pain score for women undergoing external cephalic version (ECV). The meta-analysis of 26 records found that the use of nitrous oxide did not increase the success rate of ECV or affect pain scores.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Review
Obstetrics & Gynecology
Hedi Benyamini Raischer, Manal Massalha, Rula Iskander, Ido Izhaki, Raed Salim
Summary: This study compared the use of knotless barbed sutures (KBSs) and conventional smooth sutures for uterine incision closure in cesarean section. The use of KBSs was found to be associated with decreased closure time and less frequent need for additional hemostatic sutures. Other perioperative outcomes were not affected, but the risk of postoperative ileus was reduced.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2022)
Article
Multidisciplinary Sciences
Oshrat Ben-Hamo, Ido Izhaki, Rachel Ben-Shlomo, Baruch Rinkevich
Summary: Through studying a population of Botryllus schlosseri, researchers discovered three co-existing novel life-history strategies that are achieved through colonial fission. These strategies originate from a stable environment and exhibit high within-strategy variation in traits. Six traits showed significant differences among the strategies.
SCIENTIFIC REPORTS
(2022)
Editorial Material
Endocrinology & Metabolism
Johnny S. Younis, Nora Shapso, Ido Izhaki
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Ornithology
Yosef Kiat, Ido Izhaki
Summary: Split moult is an adaptive strategy to cope with time constraints, mainly occurring among long-distance migrants and species wintering in northern or temperate zones. The conclusions of previous studies may be flawed, as split moult is not initiated during the birds' first winter. Although there is decoupling between primary and secondary feathers, there is no difference in moult sequence, which is a common mechanism among many passerines.
Article
Remote Sensing
Dor Keshet, Anna Brook, Dan Malkinson, Ido Izhaki, Motti Charter
Summary: This study found that using drones can better monitor rodent activity in fields. By calculating burrow numbers and biomass, farmers can utilize precision agriculture methods to control rodents efficiently and reduce pesticide use.
Article
Biodiversity Conservation
Roy Talbi, Yoni Gavish, Ido Izhaki, Avi Bar-Massada
Summary: In this study, the researchers explored the benefits and adverse effects of cattle egrets on agriculture and adjacent ecosystems. They found that the expansion of cattle egrets in Mediterranean agroecosystems was facilitated by cattle grazing and human activities. While cattle egrets function as pest control agents in croplands, they also act as harmful predators in natural habitats.
BIOLOGICAL CONSERVATION
(2023)
Article
Ornithology
Ron Haran, David Troupin, Ido Izhaki
Summary: CapsuleDead Sea Sparrows transferred their breeding colony to a new, less arid zone within a nature reserve due to changes in their historical breeding colony location. Using GIS layers, we found that factors affecting their nest site preference included distance from human activity, proximity to historic springs, and areas affected by fire. The birds gradually moved to the new areas exposed by the retreating Dead Sea, highlighting the importance of understanding natural and anthropogenic influences in managing breeding sites and planning for their protection.
Article
Chemistry, Multidisciplinary
R. Sela, B. K. Hammer, M. Halpern
Summary: Vibrio cholerae is the causative agent of cholera and infects millions of people annually. Chironomids are aquatic insects that act as hosts for V. cholerae. Non-toxigenic strains of V. cholerae can increase the production of high cell density-controlled genes in a toxigenic strain, potentially reducing the production of cholera toxin.
ISRAEL JOURNAL OF CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Beny Trabelcy, Nimrod Shteindel, Maya Lalzar, Ido Izhaki, Yoram Gerchman
Summary: The researchers have found that specific bacteria capable of consuming plants' secondary metabolites can change the interactions between plants and frugivores, benefiting both parties. While plants produce fleshy fruits to attract fruit-eating animals for seed dispersal, digestion of seeds by animals reduces plant fitness. The plant Ochradenus baccatus uses the myrosinase-glucosinolates system to protect its seeds, and the study shows that digestion of O. baccatus fruits is hindered in naive birds, but unaffected in experienced birds. Pantoea bacteria, found in the guts of experienced birds as well as the fruits, thrive on the hydrolysis products of glucosinolates and protect both naive birds and plant seedlings from their effects.
NATURE COMMUNICATIONS
(2023)
Review
Nutrition & Dietetics
Enav Yefet, Liron Bar, Ido Izhaki, Rula Iskander, Manal Massalha, Johnny S. S. Younis, Zohar Nachum
Summary: This systematic review and meta-analysis of randomized controlled trials aimed to evaluate the effects of probiotic supplements on glycemic control and metabolic parameters in women with gestational diabetes mellitus (GDM). The results showed that compared to placebo, women receiving probiotic supplements had significantly lower fasting serum glucose, insulin, homeostatic model assessment for insulin resistance (HOMA-IR), triglycerides, total cholesterol, and VLDL levels. The use of probiotic supplements containing Lactobacillus acidophilus also led to decreased neonatal birth weight.
Article
Multidisciplinary Sciences
Oshrat Ben-Hamo, Ido Izhaki, Rachel Ben-Shlomo, Baruch Rinkevich
Summary: By studying the life cycle of Botryllus schlosseri, it was found that different life history strategies lead to different aging processes, forming a novel aging phenomenon called Orshina rhythm, which includes important components such as reproduction, lifespan, death, rejuvenation, and fission events.
SCIENTIFIC REPORTS
(2023)
Editorial Material
Oncology
Johnny S. Younis, Ido Izhaki
FRONTIERS IN ONCOLOGY
(2023)
Letter
Microbiology
Malka Halpern
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Tamir Ofek, Maya Lalzar, Ido Izhaki, Malka Halpern
Summary: This study aimed to understand the relationship between the health condition of hybrid tilapia and the composition of microbiota in the intestine and spleen. The results showed significant differences in microbiota composition between healthy and diseased fish, as well as between the intestine and spleen of fish with the same health condition. The microbiota diversity of healthy fish was also significantly different from that of diseased fish.