HIV-1 Nef Signaling in Intestinal Mucosa Epithelium Suggests the Existence of an Active Inter-kingdom Crosstalk Mediated by Exosomes

The Contribution of Extracellular Nef to HIV-Induced Pathogenesis

(2015) Eleonora Olivetta et al.   CURRENT DRUG TARGETS

Antiviral action countered by Nef

(2015) Christopher Aiken   NATURE

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

(2015) Yoshiko Usami et al.   NATURE

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

(2015) Annachiara Rosa et al.   NATURE

Exosomes: Implications in HIV-1 Pathogenesis

(2015) Marisa Madison et al.   Viruses-Basel

Transcriptomic Analysis of mRNAs in Human Monocytic Cells Expressing the HIV-1 Nef Protein and Their Exosomes

(2015) Madeeha Aqil et al.   Biomed Research International

Extracellular vesicles from infected cells: potential for direct pathogenesis

(2015) Angela Schwab et al.   Frontiers in Microbiology

Exosomes from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells License Quiescent CD4+ T Lymphocytes To Replicate HIV-1 through a Nef- and ADAM17-Dependent Mechanism

(2014) C. Arenaccio et al.   JOURNAL OF VIROLOGY

MicroRNAs: New therapeutic targets for intestinal barrier dysfunction

(2014) Lin Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Exosomes in the gut

(2014) Lesley E. Smythies et al.   Frontiers in Immunology

MicroRNAs and HIV-1 Infection: Antiviral Activities and Beyond

(2013) Gokul Swaminathan et al.   JOURNAL OF MOLECULAR BIOLOGY

HIV-1 Nef Sequence and Functional Compartmentalization in the Gut Is Not Due to Differential Cytotoxic T Lymphocyte Selective Pressure

(2013) Martha J. Lewis et al.   PLoS One

The HIV-1 Nef Protein Binds Argonaute-2 and Functions as a Viral Suppressor of RNA Interference

(2013) Madeeha Aqil et al.   PLoS One

HIV: Cell Binding and Entry

(2013) C. B. Wilen et al.   Cold Spring Harbor Perspectives in Medicine

Roles of exosomes and microvesicles in disease pathogenesis

(2012) Shin-ichiro Ohno et al.   ADVANCED DRUG DELIVERY REVIEWS

HIV infection and the intestinal mucosal barrier

(2012) Hans-Jörg Epple et al.   Annals of the New York Academy of Sciences

MicroRNAs in HIV-1 infection: an integration of viral and cellular interaction at the genomic level

(2012) Neil H. Tan Gana et al.   Frontiers in Microbiology

MicroRNA Regulation of Intestinal Epithelial Tight Junction Permeability

(2011) Dongmei Ye et al.   GASTROENTEROLOGY

Interplay between HIV-1 infection and host microRNAs

(2011) Guihua Sun et al.   NUCLEIC ACIDS RESEARCH

Exogenous HIV-1 Nef Upsets the IFN-γ-Induced Impairment of Human Intestinal Epithelial Integrity

(2011) Maria Giovanna Quaranta et al.   PLoS One

The HIV-1 Transactivator Factor (Tat) Induces Enterocyte Apoptosis through a Redox-Mediated Mechanism

(2011) Vittoria Buccigrossi et al.   PLoS One

Effects of HIV-1 Nef on Virus Co-receptor Expression and Cytokine Release in Human Bladder, Laryngeal, and Intestinal Epithelial Cell Lines

(2011) Maria Giovanna Quaranta et al.   VIRAL IMMUNOLOGY

Genetic Characterization of HIV Type 1 Nef-Induced Vesicle Secretion

(2010) Syed A. Ali et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Exposure to HIV-1 Directly Impairs Mucosal Epithelial Barrier Integrity Allowing Microbial Translocation

(2010) Aisha Nazli et al.   PLoS Pathogens

Immunoregulatory effects of HIV-1 Nef protein

(2009) Maria Giovanna Quaranta et al.   BIOFACTORS

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells

(2009) Metka Lenassi et al.   TRAFFIC

Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication

(2008) Jasmine K Ahluwalia et al.   Retrovirology