Genetic and Dietary Iron Overload Differentially Affect the Course of Salmonella Typhimurium Infection

Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice

(2016) Susanna Canali et al.   BLOOD

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations

(2016) Alexander R. Moschen et al.   Cell Host & Microbe

Heme oxygenase 1 controls early innate immune response of macrophages toSalmonellaTyphimurium infection

(2016) Anna-Maria Mitterstiller et al.   CELLULAR MICROBIOLOGY

A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity

(2016) Hiu Chuen Lok et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induced Disruption of the Iron-Regulatory Hormone Hepcidin Inhibits Acute Inflammatory Hypoferraemia

(2016) Andrew E. Armitage et al.   Journal of Innate Immunity

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

(2016) Igor Theurl et al.   NATURE MEDICINE

Hereditary Hemochromatosis Predisposes Mice to Yersinia pseudotuberculosis Infection Even in the Absence of the Type III Secretion System

(2016) Halie K. Miller et al.   Frontiers in Cellular and Infection Microbiology

DksA-Dependent Transcriptional Regulation in Salmonella Experiencing Nitrosative Stress

(2016) Matthew A. Crawford et al.   Frontiers in Microbiology

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

(2015) Manfred Nairz et al.   Cell Host & Microbe

Hepcidin-Induced Hypoferremia Is a Critical Host Defense Mechanism against the Siderophilic Bacterium Vibrio vulnificus

(2015) João Arezes et al.   Cell Host & Microbe

Lipocalin-2 ensures host defense againstSalmonellaTyphimurium by controlling macrophage iron homeostasis and immune response

(2015) Manfred Nairz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Contrasting regulation of macrophage iron homeostasis in response to infection with Listeria monocytogenes depending on localization of bacteria

(2015) David Haschka et al.   Metallomics

Lipocalin 2-Dependent Inhibition of Mycobacterial Growth in Alveolar Epithelium

(2014) H. Saiga et al.   JOURNAL OF IMMUNOLOGY

Protective Immunity to Systemic Infection with Attenuated Salmonella enterica serovar Enteritidis in the Absence of IL-12 Is Associated with IL-23-Dependent IL-22, but Not IL-17

(2014) S. M. Schulz et al.   JOURNAL OF IMMUNOLOGY

Identification of erythroferrone as an erythroid regulator of iron metabolism

(2014) Léon Kautz et al.   NATURE GENETICS

Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasis

(2014) Don-Kyu Kim et al.   NATURE MEDICINE

Neisseria gonorrhoeae Modulates Iron-Limiting Innate Immune Defenses in Macrophages

(2014) Susu M. Zughaier et al.   PLoS One

Iron at the interface of immunity and infection

(2014) Manfred Nairz et al.   Frontiers in Pharmacology

Probiotic Bacteria Reduce Salmonella Typhimurium Intestinal Colonization by Competing for Iron

(2013) Elisa Deriu et al.   Cell Host & Microbe

Liver transplantation normalizes serum hepcidin level and cures iron metabolism alterations inHFEhemochromatosis

(2013) Edouard Bardou-Jacquet et al.   HEPATOLOGY

The FeoC Protein Leads to High Cellular Levels of the Fe(II) Transporter FeoB by Preventing FtsH Protease Regulation of FeoB in Salmonella enterica

(2013) H. Kim et al.   JOURNAL OF BACTERIOLOGY

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

(2013) Manfred Nairz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipocalin-2 ameliorates granulocyte functionality

(2012) Andrea Schroll et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutrophil gelatinase-associated lipocalin and interleukin-10 regulate intramacrophage Chlamydia pneumoniae replication by modulating intracellular iron homeostasis

(2012) Rosa Bellmann-Weiler et al.   IMMUNOBIOLOGY

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

(2012) Flavia D’Alessio et al.   JOURNAL OF HEPATOLOGY

Lipocalin 2 Deficiency Dysregulates Iron Homeostasis and Exacerbates Endotoxin-Induced Sepsis

(2012) G. Srinivasan et al.   JOURNAL OF IMMUNOLOGY

Hereditary Hemochromatosis Restores the Virulence of Plague Vaccine Strains

(2012) L. E. Quenee et al.   JOURNAL OF INFECTIOUS DISEASES

High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption

(2012) Thomas Sonnweber et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Hepcidin and the Iron-Infection Axis

(2012) H. Drakesmith et al.   SCIENCE

Hepcidin regulation by innate immune and infectious stimuli

(2011) A. E. Armitage et al.   BLOOD

Erythropoietin Contrastingly Affects Bacterial Infection and Experimental Colitis by Inhibiting Nuclear Factor-κB-Inducible Immune Pathways

(2011) Manfred Nairz et al.   IMMUNITY

Salmonella – At Home in the Host Cell

(2011) Preeti Malik-Kale et al.   Frontiers in Microbiology

The struggle for iron - a metal at the host-pathogen interface

(2010) Manfred Nairz et al.   CELLULAR MICROBIOLOGY

Divergent modulation of Chlamydia pneumoniae infection cycle in human monocytic and endothelial cells by iron, tryptophan availability and interferon gamma

(2010) Rosa Bellmann-Weiler et al.   IMMUNOBIOLOGY

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2

(2009) M. Nairz et al.   BLOOD

Growth differentiation factor 15 in anaemia of chronic disease, iron deficiency anaemia and mixed type anaemia

(2009) Igor Theurl et al.   BRITISH JOURNAL OF HAEMATOLOGY

A Precious Metal Heist

(2009) Eric P. Skaar   Cell Host & Microbe

Lipocalin-2 Resistance Confers an Advantage to Salmonella enterica Serotype Typhimurium for Growth and Survival in the Inflamed Intestine

(2009) Manuela Raffatellu et al.   Cell Host & Microbe

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

(2009) Daniel F. Wallace et al.   HEPATOLOGY

Lipocalin 2 Is Required for Pulmonary Host Defense against Klebsiella Infection

(2009) Y. R. Chan et al.   JOURNAL OF IMMUNOLOGY

Genetic mechanisms and modifying factors in hereditary hemochromatosis

(2009) Günter Weiss   Nature Reviews Gastroenterology & Hepatology

Selective Inhibition of Type III Secretion Activated Signaling by the Salmonella Effector AvrA

(2009) Fangyong Du et al.   PLoS Pathogens

Mucosal Lipocalin 2 Has Pro-Inflammatory and Iron-Sequestering Effects in Response to Bacterial Enterobactin

(2009) Michael A. Bachman et al.   PLoS Pathogens

Iron depletion limits intracellular bacterial growth in macrophages

(2008) P. N. Paradkar et al.   BLOOD

Measurement of urinary hepcidin levels by SELDI-TOF-MS in HFE-hemochromatosis

(2008) Claudia Bozzini et al.   BLOOD CELLS MOLECULES AND DISEASES

Hfe Acts in Hepatocytes to Prevent Hemochromatosis

(2008) Maja Vujić Spasić et al.   Cell Metabolism

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

(2008) Paul J. Schmidt et al.   Cell Metabolism

Nramp1 drives an accelerated inflammatory response duringSalmonella-induced colitis in mice

(2008) Yanet Valdez et al.   CELLULAR MICROBIOLOGY

Interferon‐γ limits the availability of iron for intramacrophageSalmonella typhimurium

(2008) Manfred Nairz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-23 Orchestrates Mucosal Responses to Salmonella enterica Serotype Typhimurium in the Intestine

(2008) I. Godinez et al.   INFECTION AND IMMUNITY

Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression

(2008) Milan Theurl et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Iron regulated genes of Salmonella enterica serovar Typhimurium in response to norepinephrine and the requirement of fepDGC for norepinephrine-enhanced growth

(2008) Bradley L. Bearson et al.   MICROBES AND INFECTION

Biosynthesis and IroC-dependent export of the siderophore salmochelin are essential for virulence of Salmonella enterica serovar Typhimurium

(2008) Marie-Laure V. Crouch et al.   MOLECULAR MICROBIOLOGY

Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

(2008) Manuela Raffatellu et al.   NATURE MEDICINE

A Heme Export Protein Is Required for Red Blood Cell Differentiation and Iron Homeostasis

(2008) S. B. Keel et al.   SCIENCE

Modulation of macrophage iron transport by Nramp1 (Slc11a1)

(2007) Gernot Fritsche et al.   IMMUNOBIOLOGY