Oncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases
出版年份 2017 全文链接
标题
Oncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases
作者
关键词
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出版物
eLife
Volume 6, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2017-03-27
DOI
10.7554/elife.22451
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Histone Deacetylases with Antagonistic Roles in Saccharomyces cerevisiae Heterochromatin Formation
- (2016) Deborah M. Thurtle-Schmidt et al. GENETICS
- Saccharomyces cerevisiaeForms d-2-Hydroxyglutarate and Couples Its Degradation to d-Lactate Formation via a Cytosolic Transhydrogenase
- (2016) Julia Becker-Kettern et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Riches of phenotype computationally extracted from microbial colonies
- (2016) Tzu-Yu Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone Deacetylases with Antagonistic Roles in Saccharomyces cerevisiae Heterochromatin Formation
- (2016) Deborah M. Thurtle-Schmidt et al. GENETICS
- Isocitrate dehydrogenase mutations in gliomas
- (2015) Matthew S. Waitkus et al. NEURO-ONCOLOGY
- Heritable capture of heterochromatin dynamics in Saccharomyces cerevisiae
- (2015) Anne E Dodson et al. eLife
- The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation
- (2014) Remco J. Molenaar et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Mutant IDH1 Enhances the Production of 2-Hydroxyglutarate Due to Its Kinetic Mechanism
- (2013) Alan R. Rendina et al. BIOCHEMISTRY
- Disruption of Wild-Type IDH1 Suppresses D-2-Hydroxyglutarate Production in IDH1-Mutated Gliomas
- (2012) G. Jin et al. CANCER RESEARCH
- The Potential for Isocitrate Dehydrogenase Mutations to Produce 2-Hydroxyglutarate Depends on Allele Specificity and Subcellular Compartmentalization
- (2012) Patrick S. Ward et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TET2 Mutations in Acute Myeloid Leukemia (AML): Results From a Comprehensive Genetic and Clinical Analysis of the AML Study Group
- (2012) Verena I. Gaidzik et al. JOURNAL OF CLINICAL ONCOLOGY
- IDH mutation impairs histone demethylation and results in a block to cell differentiation
- (2012) Chao Lu et al. NATURE
- IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
- (2012) Sevin Turcan et al. NATURE
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
- (2011) Rasheduzzaman Chowdhury et al. EMBO REPORTS
- Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH Mutations in Glioblastoma
- (2011) Daniel Krell et al. PLoS One
- Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 A Resolution
- (2011) K.-J. Armache et al. SCIENCE
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
- Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
- (2010) Stefan Gross et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism
- (2010) Z. J. Reitman et al. JNCI-Journal of the National Cancer Institute
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- The establishment of gene silencing at single-cell resolution
- (2009) Erin A Osborne et al. NATURE GENETICS
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
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