E3 ubiquitin ligase Bre1 couples sister chromatid cohesion establishment to DNA replication in Saccharomyces cerevisiae

Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome

(2016) Catarina P. Samora et al.   MOLECULAR CELL

Histone H2B mono-ubiquitylation maintains genomic integrity at stalled replication forks

(2016) Matthew R. Northam et al.   NUCLEIC ACIDS RESEARCH

The eukaryotic CMG helicase pumpjack and integration into the replisome

(2016) Jingchuan Sun et al.   Nucleus

The eukaryotic CMG helicase pumpjack and integration into the replisome

(2016) Jingchuan Sun et al.   Nucleus

Recruitment of Mcm10 to Sites of Replication Initiation Requires Direct Binding to the Minichromosome Maintenance (MCM) Complex

(2015) Max E. Douglas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mcm10 coordinates the timely assembly and activation of the replication fork helicase

(2015) Patricia Perez-Arnaiz et al.   NUCLEIC ACIDS RESEARCH

Cell-Cycle-Regulated Interaction between Mcm10 and Double Hexameric Mcm2-7 Is Required for Helicase Splitting and Activation during S Phase

(2015) Yun Quan et al.   Cell Reports

The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity

(2015) Musinu Zakari et al.   PLoS Genetics

Surface Spreading and Immunostaining of Yeast Chromosomes

(2015) Jennifer Grubb et al.   Jove-Journal of Visualized Experiments

Catalysis-dependent stabilization of Bre1 fine-tunes histone H2B ubiquitylation to regulate gene transcription

(2014) Glenn G. Wozniak et al.   GENES & DEVELOPMENT

A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome

(2014) Aline C. Simon et al.   NATURE

Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity

(2014) Laia Sadeghi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MCM10: One tool for all—Integrity, maintenance and damage control

(2014) Yee Mon Thu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis

(2013) Laura L. Thompson et al.   CANCER AND METASTASIS REVIEWS

An Eco1-independent sister chromatid cohesion establishment pathway in S. cerevisiae

(2013) Vanessa Borges et al.   CHROMOSOMA

The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability

(2013) Lamia Wahba et al.   eLife

Cohesin: A guardian of genome integrity

(2012) Gunjan D. Mehta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The enigmatic role of H2Bub1 in cancer

(2012) Steven A. Johnsen   FEBS LETTERS

DNA Replication Origin Function Is Promoted by H3K4 Di-methylation in Saccharomyces cerevisiae

(2012) L. F. Rizzardi et al.   GENETICS

Cohesin Association to Replication Sites Depends on Rad50 and Promotes Fork Restart

(2012) Mireille Tittel-Elmer et al.   MOLECULAR CELL

A Role for H2B Ubiquitylation in DNA Replication

(2012) Kelly M. Trujillo et al.   MOLECULAR CELL

A Positive Feedback Loop Links Opposing Functions of P-TEFb/Cdk9 and Histone H2B Ubiquitylation to Regulate Transcript Elongation in Fission Yeast

(2012) Miriam Sansó et al.   PLoS Genetics

Chromatin Signaling to Kinetochores: Transregulation of Dam1 Methylation by Histone H2B Ubiquitination

(2011) John A. Latham et al.   CELL

Cdk1-Dependent Destruction of Eco1 Prevents Cohesion Establishment after S Phase

(2011) Nicholas A. Lyons et al.   MOLECULAR CELL

Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination

(2011) Kyosuke Nakamura et al.   MOLECULAR CELL

Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks

(2011) Lilach Moyal et al.   MOLECULAR CELL

Cohesin: a catenase with separate entry and exit gates?

(2011) Kim Nasmyth   NATURE CELL BIOLOGY

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression

(2011) C. Zimmermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ctf4p facilitates Mcm10p to promote DNA replication in budding yeast

(2010) Jiafeng Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Stable Interaction between the Human Proliferating Cell Nuclear Antigen Loader Complex Ctf18-Replication Factor C (RFC) and DNA Polymerase ϵ Is Mediated by the Cohesion-specific Subunits, Ctf18, Dcc1, and Ctf8

(2010) Takeshi Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bre1p-mediated histone H2B ubiquitylation regulates apoptosis in Saccharomyces cerevisiae

(2010) D. Walter et al.   JOURNAL OF CELL SCIENCE

An Smc3 Acetylation Cycle Is Essential for Establishment of Sister Chromatid Cohesion

(2010) Frederic Beckouët et al.   MOLECULAR CELL

GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome

(2010) Matthew D Sekedat et al.   Molecular Systems Biology

Deficiency in Bre1 Impairs Homologous Recombination Repair and Cell Cycle Checkpoint Response to Radiation Damage in Mammalian Cells

(2010) Sophia B. Chernikova et al.   RADIATION RESEARCH

Cohesin: Its Roles and Mechanisms

(2009) Kim Nasmyth et al.   Annual Review of Genetics

Budding Yeast Wpl1(Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion-Establishing Reaction

(2009) Takashi Sutani et al.   CURRENT BIOLOGY

A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase α within the eukaryotic replisome

(2009) Agnieszka Gambus et al.   EMBO JOURNAL

Replisome progression complex links DNA replication to sister chromatid cohesion inXenopusegg extracts

(2009) Hiroshi Tanaka et al.   GENES TO CELLS

Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1

(2009) Shima Nakanishi et al.   JOURNAL OF CELL BIOLOGY

Building Sister Chromatid Cohesion: Smc3 Acetylation Counteracts an Antiestablishment Activity

(2009) Benjamin D. Rowland et al.   MOLECULAR CELL

Cohesin acetylation speeds the replication fork

(2009) Marie-Emilie Terret et al.   NATURE

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability

(2009) M. B. Chandrasekharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cohesin complex and its roles in chromosome biology

(2008) J.-M. Peters et al.   GENES & DEVELOPMENT

H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation

(2008) Alastair B. Fleming et al.   MOLECULAR CELL

The cohesin ring concatenates sister DNA molecules

(2008) Christian H. Haering et al.   NATURE

Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation

(2008) Adeline Vitaliano-Prunier et al.   NATURE CELL BIOLOGY

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

(2008) Neri Minsky et al.   NATURE CELL BIOLOGY

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

(2008) T. D. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Molecular Determinant for the Establishment of Sister Chromatid Cohesion

(2008) E. U nal et al.   SCIENCE

Eco1-Dependent Cohesin Acetylation During Establishment of Sister Chromatid Cohesion

(2008) T. R. Ben-Shahar et al.   SCIENCE

Cell Cycle– and Chaperone-Mediated Regulation of H3K56ac Incorporation in Yeast

(2008) Tommy Kaplan et al.   PLoS Genetics