期刊
BIOTECHNOLOGY JOURNAL
卷 13, 期 5, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/biot.201700170
关键词
lab-on-chip; micro; nanofluidics; quantitative biology; synthetic biology; systems biology
资金
- National Natural Science Foundation of China [31570095, 11504399, 31770111, 31700090]
- Shenzhen Science Technology and Innovation Commission [JCYJ20170307163830109, JCYJ20170413153329565]
- Guangdong Natural Science Funds for Distinguished Young Scholar Grant [S2013050016987]
- Shenzhen Peacock Team Project [KQTD2015033117210153]
- Shenzhen Peacock Project [KQCX2015033117354154]
- SIAT Innovation Program for Excellent Young Researchers [2017003]
- Instrumental project from Chinese Academy of Science [YJKYYQ20170063]
Quantitative biology is dedicated to taking advantage of quantitative reasoning and advanced engineering technologies to make biology more predictable. Microfluidics, as an emerging technique, provides new approaches to precisely control fluidic conditions on small scales and collect data in high-throughput and quantitative manners. In this review, the authors present the relevant applications of microfluidics to quantitative biology based on two major categories (channel-based microfluidics and droplet-based microfluidics), and their typical features. We also envision some other microfluidic techniques that may not be employed in quantitative biology right now, but have great potential in the near future.
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