The Effect of Osteopontin on Microglia

The Role of Osteopontin in Neurodegenerative Diseases

(2018) Miryam Carecchio et al.   JOURNAL OF ALZHEIMERS DISEASE

Old Maids: Aging and Its Impact on Microglia Function

(2017) Edward Koellhoffer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Osteopontin directly modulates cytokine expression of primary microglia and increases their survival

(2016) Monika Rabenstein et al.   JOURNAL OF NEUROIMMUNOLOGY

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

Increased Expression of Osteopontin in Retinal Degeneration Induced by Blue Light-Emitting Diode Exposure in Mice

(2016) Seung Wook Chang et al.   Frontiers in Molecular Neuroscience

Increased neurotrophic factor levels in ventral mesencephalic cultures do not explain the protective effect of osteopontin and the synthetic 15-mer RGD domain against MPP+ toxicity

(2015) Lauren Broom et al.   EXPERIMENTAL NEUROLOGY

Osteopontin deficiency aggravates hepatic injury induced by ischemia–reperfusion in mice

(2014) S Patouraux et al.   Cell Death & Disease

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

(2013) Tamara Tchkonia et al.   JOURNAL OF CLINICAL INVESTIGATION

Aging enhances classical activation but mitigates alternative activation in the central nervous system

(2013) Daniel C. Lee et al.   NEUROBIOLOGY OF AGING

Minocycline selectively inhibits M1 polarization of microglia

(2013) K Kobayashi et al.   Cell Death & Disease

A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

(2013) Isaac M. Chiu et al.   Cell Reports

Osteopontin alters the functional profile of porcine microgliain vitro

(2012) Bart R. Tambuyzer et al.   CELL BIOLOGY INTERNATIONAL

Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS

(2012) Bing Liao et al.   EXPERIMENTAL NEUROLOGY

Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin αVβ3 engagement and PI3K/pAkt/NFκB signaling

(2011) Raquel Urtasun et al.   HEPATOLOGY

Pre- and post-translational regulation of osteopontin in cancer

(2011) Pieter H. Anborgh et al.   Journal of Cell Communication and Signaling

Osteopontin Expression is an Independent Adverse Prognostic Factor in Resectable Gastrointestinal Stromal Tumor and its Interaction with CD44 Promotes Tumor Proliferation

(2010) Kai-Hsi Hsu et al.   ANNALS OF SURGICAL ONCOLOGY

Oxidized low-density lipoprotein increases osteopontin expression by generation of oxidative stress

(2010) Cécile Mazière et al.   FREE RADICAL BIOLOGY AND MEDICINE

Osteopontin: Correlation with phagocytosis by brain macrophages in a rat model of stroke

(2010) Yoo-Jin Shin et al.   GLIA

Phosphate Regulates Osteopontin Gene Transcription

(2009) S. Fatherazi et al.   JOURNAL OF DENTAL RESEARCH

Osteopontin Enhances Phagocytosis through a Novel Osteopontin Receptor, the  X 2 Integrin

(2009) L. Schack et al.   JOURNAL OF IMMUNOLOGY

Osteopontin modulates angiotensin II–induced inflammation, oxidative stress, and fibrosis of the kidney

(2009) Talya Wolak et al.   KIDNEY INTERNATIONAL

Osteopontin: Role in immune regulation and stress responses

(2008) Kathryn X. Wang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Nasal Administration of Osteopontin Peptide Mimetics Confers Neuroprotection in Stroke

(2008) Kristian P Doyle et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microglia: gatekeepers of central nervous system immunology

(2008) Bart R. Tambuyzer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease

(2008) Oliver Wirths et al.   NEUROBIOLOGY OF AGING