Gemcitabine–camptothecin conjugates: a hybrid prodrug for controlled drug release and synergistic therapeutics

Comparison of the protective effect of self-emulsifying peptide drug delivery systems towards intestinal proteases and glutathione

(2017) Gergely Hetényi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Stimuli-responsive multifunctional glyconanoparticle platforms for targeted drug delivery and cancer cell imaging

(2017) Xumeng Wu et al.   Chemical Science

Encapsulation of a nitric oxide donor into a liposome to boost the enhanced permeation and retention (EPR) effect

(2017) Yu Tahara et al.   MedChemComm

Rapidly cell-penetrating and reductive milieu-responsive nanoaggregates assembled from an amphiphilic folate-camptothecin prodrug for enhanced drug delivery and controlled release

(2017) Zhigang Xu et al.   Biomaterials Science

Combining Two-Photon-Activated Fluorescence Resonance Energy Transfer and Near-Infrared Photothermal Effect of Unimolecular Micelles for Enhanced Photodynamic Therapy

(2016) Yu Huang et al.   ACS Nano

Characterization of IgG2 Disulfide Bonds with LC/MS/MS and Postcolumn Online Reduction

(2016) Hongji Liu et al.   ANALYTICAL CHEMISTRY

Materials and methods for delivery of biological drugs

(2016) Alexander N. Zelikin et al.   Nature Chemistry

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

(2016) Hong-Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From structures to functions: insights into exosomes as promising drug delivery vehicles

(2016) Jinghua Ren et al.   Biomaterials Science

Short peptide based nanotubes capable of effective curcumin delivery for treating drug resistant malaria

(2016) Shadab Alam et al.   JOURNAL OF NANOBIOTECHNOLOGY

Synergistic Combination Chemotherapy of Camptothecin and Floxuridine through Self-Assembly of Amphiphilic Drug–Drug Conjugate

(2015) Minxi Hu et al.   BIOCONJUGATE CHEMISTRY

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Unimolecular micelles of amphiphilic cyclodextrin-core star-like block copolymers for anticancer drug delivery

(2015) Zhigang Xu et al.   CHEMICAL COMMUNICATIONS

Hyperbranched polyphosphates: synthesis, functionalization and biomedical applications

(2015) Jinyao Liu et al.   CHEMICAL SOCIETY REVIEWS

Volume of Distribution in Drug Design

(2015) Dennis A. Smith et al.   JOURNAL OF MEDICINAL CHEMISTRY

Light-Triggered, Self-Immolative Nucleic Acid-Drug Nanostructures

(2015) Xuyu Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Immunosuppressive Antibody–Drug Conjugate

(2015) Rongsheng E. Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembled Nanoparticles of Amphiphilic Twin Drug from Floxuridine and Bendamustine for Cancer Therapy

(2015) Ting Zhang et al.   MOLECULAR PHARMACEUTICS

Reduction Responsive Self-Assembled Nanoparticles Based on Disulfide-Linked Drug–Drug Conjugate with High Drug Loading and Antitumor Efficacy

(2015) Qin Song et al.   MOLECULAR PHARMACEUTICS

Self-delivery of a peptide-based prodrug for tumor-targeting therapy

(2015) Mengyun Peng et al.   Nano Research

Doxorubicin conjugated phospholipid prodrugs as smart nanomedicine platforms for cancer therapy

(2015) Haibo Wang et al.   Journal of Materials Chemistry B

Multiwalled Nanotubes Formed by Catanionic Mixtures of Drug Amphiphiles

(2014) Yi-An Lin et al.   ACS Nano

Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles

(2014) Andrew G. Cheetham et al.   CHEMICAL COMMUNICATIONS

Intracellular Protein-Responsive Supramolecules: Protein Sensing and In-Cell Construction of Inhibitor Assay System

(2014) Tatsuyuki Yoshii et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-Penetrating Hyperbranched Polyprodrug Amphiphiles for Synergistic Reductive Milieu-Triggered Drug Release and Enhanced Magnetic Resonance Signals

(2014) Xianglong Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Combination of Small Molecule Prodrug and Nanodrug Delivery: Amphiphilic Drug–Drug Conjugate for Cancer Therapy

(2014) Ping Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Disulfide Bond Bridge Insertion Turns Hydrophobic Anticancer Prodrugs into Self-Assembled Nanomedicines

(2014) Yongjun Wang et al.   NANO LETTERS

Investigating the optimal size of anticancer nanomedicine

(2014) L. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving Conventional Enhanced Permeability and Retention (EPR) Effects; What Is the Appropriate Target?

(2014) Hisataka Kobayashi et al.   Theranostics

Synergistic gene and drug tumor therapy using a chimeric peptide

(2013) Kai Han et al.   BIOMATERIALS

In vivo biodistribution and toxicology of functionalized nano-graphene oxide in mice after oral and intraperitoneal administration

(2013) Kai Yang et al.   BIOMATERIALS

Hydrophobic penetrating peptide PFVYLI-modified stealth liposomes for doxorubicin delivery in breast cancer therapy

(2013) Defu Cai et al.   BIOMATERIALS

Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking, and Drug Delivery

(2013) Xianglong Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Size-Dependent Tumor Penetration and in Vivo Efficacy of Monodisperse Drug–Silica Nanoconjugates

(2013) Li Tang et al.   MOLECULAR PHARMACEUTICS

Drug nanocrystals: In vivo performances

(2012) Lei Gao et al.   JOURNAL OF CONTROLLED RELEASE

Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities

(2012) Z. Cheng et al.   SCIENCE

Chloride channel-mediated brain glioma targeting of chlorotoxin-modified doxorubicine-loaded liposomes

(2011) Yu Xiang et al.   JOURNAL OF CONTROLLED RELEASE

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH