Cutaneous HPV8 and MmuPV1 E6 Proteins Target the NOTCH and TGF-β Tumor Suppressors to Inhibit Differentiation and Sustain Keratinocyte Proliferation

Role of Ultraviolet Radiation in Papillomavirus-Induced Disease

(2016) Aayushi Uberoi et al.   PLoS Pathogens

Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis

(2015) Martin Hufbauer et al.   Molecular Cancer

β-HPV 5 and 8 E6 Disrupt Homology Dependent Double Strand Break Repair by Attenuating BRCA1 and BRCA2 Expression and Foci Formation

(2015) Nicholas A. Wallace et al.   PLoS Pathogens

TMC8 (EVER2) attenuates intracellular signaling by Zn2+ and Ca2+ and suppresses activation of Cl− currents

(2014) Lalida Sirianant et al.   CELLULAR SIGNALLING

Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase

(2014) Amy Holloway et al.   INTERNATIONAL JOURNAL OF CANCER

Human papillomavirus type 197 is commonly present in skin tumors

(2014) L. Sara Arroyo Mühr et al.   INTERNATIONAL JOURNAL OF CANCER

The Viral Etiology of Skin Cancer

(2014) Jordan M. Meyers et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis

(2014) Andrew P. South et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Strain-Specific Properties and T Cells Regulate the Susceptibility to Papilloma Induction by Mus musculus Papillomavirus 1

(2014) Alessandra Handisurya et al.   PLoS Pathogens

Papillomavirus-associated squamous skin cancers following transplant immunosuppression: one Notch closer to control

(2013) Kate Connolly et al.   CANCER TREATMENT REVIEWS

The Human Papillomavirus Type 8 E6 Protein Interferes with NOTCH Activation during Keratinocyte Differentiation

(2013) J. M. Meyers et al.   JOURNAL OF VIROLOGY

Characterization of Mus musculus Papillomavirus 1 Infection In Situ Reveals an Unusual Pattern of Late Gene Expression and Capsid Protein Localization

(2013) A. Handisurya et al.   JOURNAL OF VIROLOGY

Secondary Infections, Expanded Tissue Tropism, and Evidence for Malignant Potential in Immunocompromised Mice Infected with Mus musculus Papillomavirus 1 DNA and Virus

(2013) N. M. Cladel et al.   JOURNAL OF VIROLOGY

Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins

(2013) K. Zanier et al.   SCIENCE

HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition

(2013) Nicholas A. Wallace et al.   VIROLOGY

SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer

(2012) N. I. Fleming et al.   CANCER RESEARCH

Cutaneous Squamous Cell Carcinoma and Human Papillomavirus: Is There an Association?

(2012) Bishr Aldabagh et al.   DERMATOLOGIC SURGERY

Activation of Cap-Dependent Translation by Mucosal Human Papillomavirus E6 Proteins Is Dependent on the Integrity of the LXXLL Binding Motif

(2012) J. M. Spangle et al.   JOURNAL OF VIROLOGY

Comprehensive Analysis of Host Cellular Interactions with Human Papillomavirus E6 Proteins Identifies New E6 Binding Partners and Reflects Viral Diversity

(2012) E. A. White et al.   JOURNAL OF VIROLOGY

TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex

(2012) Gobi Thillainadesan et al.   MOLECULAR CELL

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

(2012) Orit Rozenblatt-Rosen et al.   NATURE

Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling

(2012) N Brimer et al.   ONCOGENE

Cutaneous  -human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling

(2012) M. J. A. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses

(2012) E. A. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic pathways in disorders of epidermal differentiation

(2012) Vanessa Lopez-Pajares et al.   TRENDS IN GENETICS

Murine skin and vaginal mucosa are similarly susceptible to infection by pseudovirions of different papillomavirus classifications and species

(2012) Alessandra Handisurya et al.   VIROLOGY

HPV 5 and 8 E6 Abrogate ATR Activity Resulting in Increased Persistence of UVB Induced DNA Damage

(2012) Nicholas A. Wallace et al.   PLoS Pathogens

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

(2011) N. J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of TGFβ signaling Smads in squamous cell carcinoma

(2011) Gangwen Han et al.   Cell and Bioscience

Beta-HPV 5 and 8 E6 Promote p300 Degradation by Blocking AKT/p300 Association

(2011) Heather L. Howie et al.   PLoS Pathogens

Novel Laboratory Mouse Papillomavirus (MusPV) Infection

(2010) A. Ingle et al.   VETERINARY PATHOLOGY

Enhanced human papillomavirus type 8 oncogene expression levels are crucial for skin tumorigenesis in transgenic mice

(2010) M. Hufbauer et al.   VIROLOGY

Spontaneous tumour development in human papillomavirus type 8 E6 transgenic mice and rapid induction by UV-light exposure and wounding

(2009) G. P. Marcuzzi et al.   JOURNAL OF GENERAL VIROLOGY

Establishment of Human Papillomavirus Infection Requires Cell Cycle Progression

(2009) Dohun Pyeon et al.   PLoS Pathogens

E6 Proteins from Multiple Human Betapapillomavirus Types Degrade Bak and Protect Keratinocytes from Apoptosis after UVB Irradiation

(2008) M. P. Underbrink et al.   JOURNAL OF VIROLOGY

Notch tumor suppressor function

(2008) G P Dotto   ONCOGENE