Negative modulation of suppressive HIV-specific regulatory T cells by IL-2 adjuvanted therapeutic vaccine

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans

(2016) Petra Bacher et al.   CELL

Cutting Edge: T Regulatory Cell Depletion Reactivates Latent Simian Immunodeficiency Virus (SIV) in Controller Macaques While Boosting SIV-Specific T Lymphocytes

(2016) Tianyu He et al.   JOURNAL OF IMMUNOLOGY

Therapeutic vaccines and immunological intervention in HIV infection

(2016) Giuseppe Pantaleo et al.   Current Opinion in HIV and AIDS

Rapid induction of clinical remission by low-dose interleukin-2 in a patient with refractory SLE

(2015) Jens Y Humrich et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-2 treatment reverses effects of cAMP-responsive element modulatorα-over-expressing T cells in autoimmune-prone mice

(2015) K. Ohl et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients

(2015) Michelle Rosenzwajg et al.   JOURNAL OF AUTOIMMUNITY

Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3highregulatory T cells in humans

(2015) Makoto Miyara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decreased HIV-Specific T-Regulatory Responses Are Associated with Effective DC-Vaccine Induced Immunity

(2015) Vedran Brezar et al.   PLoS Pathogens

Administration of Low Doses of IL-2 Combined to Rapamycin Promotes Allogeneic Skin Graft Survival in Mice

(2014) C. B. Pilon et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Exploiting differential expression of the IL-7 receptor on memory T cells to modulate immune responses

(2014) John J. Zaunders et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Human antigen-specific CD4+CD25+CD134+CD39+T cells are enriched for regulatory T cells and comprise a substantial proportion of recall responses

(2014) Nabila Seddiki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dendritic cell-based therapeutic vaccine elicits polyfunctional HIV-specific T-cell immunity associated with control of viral load

(2014) Yves Lévy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effects of Low-Dose Recombinant Interleukin 2 to Promote T-Regulatory Cells in Alopecia Areata

(2014) Emeline Castela et al.   JAMA Dermatology

PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells

(2013) Erin E. West et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of Transcription Factor Phenotypes within Antigen-Specific CD4+ T Cells Using Qualitative Multiplex Single-Cell RT-PCR

(2013) Chansavath Phetsouphanh et al.   PLoS One

Low-Dose Interleukin-2 Therapy Restores Regulatory T Cell Homeostasis in Patients with Chronic Graft-Versus-Host Disease

(2013) K.-i. Matsuoka et al.   Science Translational Medicine

Regulatory T Cells Negatively Affect IL-2 Production of Effector T Cells through CD39/Adenosine Pathway in HIV Infection

(2013) Mohammad-Ali Jenabian et al.   PLoS Pathogens

Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial

(2013) Agnès Hartemann et al.   Lancet Diabetes & Endocrinology

CD4+FOXP3+ Regulatory T-Cell Subsets in Human Immunodeficiency Virus Infection

(2013) Federico Simonetta et al.   Frontiers in Immunology

Homeostasis and Function of Regulatory T Cells in HIV/SIV Infection

(2012) M. E. Moreno-Fernandez et al.   JOURNAL OF VIROLOGY

Responsiveness of HIV-specific CD4 T cells to PD-1 blockade

(2011) F. Porichis et al.   BLOOD

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis

(2011) David Saadoun et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

(2011) John Koreth et al.   NEW ENGLAND JOURNAL OF MEDICINE

gp100 Peptide Vaccine and Interleukin-2 in Patients with Advanced Melanoma

(2011) Douglas J. Schwartzentruber et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

(2010) Yenkel Grinberg-Bleyer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gut Mucosal FOXP3+ Regulatory CD4+ T Cells and Nonregulatory CD4+ T Cells Are Differentially Affected by Simian Immunodeficiency Virus Infection in Rhesus Macaques

(2010) K. Allers et al.   JOURNAL OF VIROLOGY

In vivo expansion of naive and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patients

(2010) L. Weiss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Interleukin-2 Therapy in Patients with HIV Infection

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Treatment of Metastatic Melanoma Using Interleukin-2 Alone or in Conjunction with Vaccines

(2008) F. O. Smith et al.   CLINICAL CANCER RESEARCH

Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction

(2008) Qizhi Tang et al.   IMMUNITY

Resting Regulatory CD4 T Cells: A Site of HIV Persistence in Patients on Long-Term Effective Antiretroviral Therapy

(2008) Tu-Anh Tran et al.   PLoS One