Defining Brugia malayi and Wolbachia symbiosis by stage-specific dual RNA-seq

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Theo Vos et al.   LANCET

Tissue-specific transcriptomics and proteomics of a filarial nematode and its Wolbachia endosymbiont

(2015) Ashley N. Luck et al.   BMC GENOMICS

Mechanism and structure of the bacterial type IV secretion systems

(2014) Peter J. Christie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Concurrent transcriptional profiling of Dirofilaria immitis and its Wolbachia endosymbiont throughout the nematode life cycle reveals coordinated gene expression

(2014) Ashley N Luck et al.   BMC GENOMICS

Wolbachia endosymbionts and human disease control

(2014) Barton E. Slatko et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Wolbachia lipoproteins: abundance, localisation and serology of Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6 from Brugia malayi and Aedes albopictus

(2014) Denis Voronin et al.   Parasites & Vectors

Iron Necessity: The Secret of Wolbachia's Success?

(2014) Alessandra Christina Gill et al.   PLoS Neglected Tropical Diseases

Potential involvement of Brugia malayi cysteine proteases in the maintenance of the endosymbiotic relationship with Wolbachia

(2014) Sara Lustigman et al.   International Journal for Parasitology-Drugs and Drug Resistance

Genomics of Loa loa, a Wolbachia-free filarial parasite of humans

(2013) Christopher A Desjardins et al.   NATURE GENETICS

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

One ring to rule them all: Trafficking of heme and heme synthesis intermediates in the metazoans

(2012) Iqbal Hamza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis

(2012) A. C. Darby et al.   GENOME RESEARCH

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

The Twin-Arginine Translocation Pathway in α-Proteobacteria Is Functionally Preserved Irrespective of Genomic and Regulatory Divergence

(2012) Pablo A. Nuñez et al.   PLoS One

Characterization of Transcription Factors That Regulate the Type IV Secretion System and Riboflavin Biosynthesis in Wolbachia of Brugia malayi

(2012) Zhiru Li et al.   PLoS One

Interactions of NADP-Reducing Enzymes Across Varying Environmental Conditions: A Model of Biological Complexity

(2012) Teresa Z. Rzezniczak et al.   G3-Genes Genomes Genetics

A Research Agenda for Helminth Diseases of Humans: The Problem of Helminthiases

(2012) Sara Lustigman et al.   PLoS Neglected Tropical Diseases

Filariasis in Africa—treatment challenges and prospects

(2011) A. Hoerauf et al.   CLINICAL MICROBIOLOGY AND INFECTION

Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia

(2011) S. Bennuru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Deep Sequencing Approach to Comparatively Analyze the Transcriptome of Lifecycle Stages of the Filarial Worm, Brugia malayi

(2011) Young-Jun Choi et al.   PLoS Neglected Tropical Diseases

Anti-filarial Activity of Antibiotic Therapy Is Due to Extensive Apoptosis after Wolbachia Depletion from Filarial Nematodes

(2011) Frederic Landmann et al.   PLoS Pathogens

The Sec translocase

(2010) David J.F. du Plessis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Anaplasma phagocytophilum and Ehrlichia chaffeensis type IV secretion and Ank proteins

(2010) Yasuko Rikihisa et al.   CURRENT OPINION IN MICROBIOLOGY

Mitochondrial genes for heme-dependent respiratory chain complexes are up-regulated after depletion of Wolbachia from filarial nematodes

(2010) Uta Strübing et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Lymphatic filariasis and onchocerciasis

(2010) Mark J Taylor et al.   LANCET

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Endosymbiont DNA in Endobacteria-Free Filarial Nematodes Indicates Ancient Horizontal Genetic Transfer

(2010) Samantha N. McNulty et al.   PLoS One

Differential Protein Modulation in Midguts of Aedes aegypti Infected with Chikungunya and Dengue 2 Viruses

(2010) Stéphane Tchankouo-Nguetcheu et al.   PLoS One

Asymmetric Wolbachia Segregation during Early Brugia malayi Embryogenesis Determines Its Distribution in Adult Host Tissues

(2010) Frédéric Landmann et al.   PLoS Neglected Tropical Diseases

Conservation of the Type IV Secretion System throughout Wolbachia evolution

(2009) Samuel Pichon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

WolbachiaLipoprotein Stimulates Innate and Adaptive Immunity through Toll-like Receptors 2 and 6 to Induce Disease Manifestations of Filariasis

(2009) Joseph D. Turner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Heme Biosynthetic Pathway of the Obligate Wolbachia Endosymbiont of Brugia malayi as a Potential Anti-filarial Drug Target

(2009) Bo Wu et al.   PLoS Neglected Tropical Diseases

Divalent cations stabilize GroEL under conditions of oxidative stress

(2008) Girish C. Melkani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Genetic and Functional Characterization of the Type IV Secretion System in Wolbachia

(2008) E. Rances et al.   JOURNAL OF BACTERIOLOGY

The Endosymbiont Wolbachia pipientis Induces the Expression of Host Antioxidant Proteins in an Aedes albopictus Cell Line

(2008) Lesley J. Brennan et al.   PLoS One

Ankyrin Repeat Proteins Comprise a Diverse Family of Bacterial Type IV Effectors

(2008) X. Pan et al.   SCIENCE