Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach
出版年份 2017 全文链接
标题
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach
作者
关键词
DNA methylation, Body mass index, Gene expression, Blood, Genetic loci, Obesity, DNA replication, Epigenetics
出版物
PLOS MEDICINE
Volume 14, Issue 1, Pages e1002215
出版商
Public Library of Science (PLoS)
发表日期
2017-01-18
DOI
10.1371/journal.pmed.1002215
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- DNA Methylation and BMI: Investigating Identified Methylation Sites atHIF3Ain a Causal Framework
- (2016) Rebecca C. Richmond et al. DIABETES
- Serum Mac-2 binding protein is a novel biomarker for chronic pancreatitis
- (2016) Tomohiro Maekawa et al. WORLD JOURNAL OF GASTROENTEROLOGY
- eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data
- (2016) Charles E. Breeze et al. Cell Reports
- Epigenetic associations of type 2 diabetes and BMI in an Arab population
- (2016) Wadha A. Al Muftah et al. Clinical Epigenetics
- Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations
- (2015) Sonia Shah et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes
- (2015) Rachel J. Perry et al. CELL
- DNA Methylation of Lipid-Related Genes Affects Blood Lipid LevelsCLINICAL PERSPECTIVE
- (2015) Liliane Pfeiffer et al. Circulation-Cardiovascular Genetics
- Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease
- (2015) Jingzhong Ding et al. DIABETES
- Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood
- (2015) R C Huang et al. Epigenetics
- Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes
- (2015) Lara Bellini et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers
- (2015) Yoshihiro Kamada et al. HEPATOLOGY
- Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci
- (2015) Ellen W. Demerath et al. HUMAN MOLECULAR GENETICS
- Differential DNA Methylation in Relation to Age and Health Risks of Obesity
- (2015) María Mansego et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sphingolipids in cardiovascular diseases and metabolic disorders
- (2015) Sonia Borodzicz et al. Lipids in Health and Disease
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Genetic studies of body mass index yield new insights for obesity biology
- (2015) Adam E. Locke et al. NATURE
- Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference
- (2015) Stella Aslibekyan et al. Obesity
- NIH working group report-using genomic information to guide weight management: From universal to precision treatment
- (2015) Molly S. Bray et al. Obesity
- Gut microbiota-derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity
- (2015) L. -G. Hersoug et al. Obesity Reviews
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- Mendelian randomization: applications and limitations in epigenetic studies
- (2015) Caroline L Relton et al. Epigenomics
- DNA Methylation of Lipid-Related Genes Affects Blood Lipid LevelsCLINICAL PERSPECTIVE
- (2015) Liliane Pfeiffer et al. Circulation-Cardiovascular Genetics
- Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study
- (2015) John C Chambers et al. Lancet Diabetes & Endocrinology
- The sex-specific association between BMI and coronary heart disease: a systematic review and meta-analysis of 95 cohorts with 1·2 million participants
- (2015) Morgana L Mongraw-Chaffin et al. Lancet Diabetes & Endocrinology
- Epigenome-Wide Association Study of Fasting Blood Lipids in the Genetics of Lipid-Lowering Drugs and Diet Network Study
- (2014) Marguerite R. Irvin et al. CIRCULATION
- Adipocyte ATP-Binding Cassette G1 Promotes Triglyceride Storage, Fat Mass Growth, and Human Obesity
- (2014) Eric Frisdal et al. DIABETES
- Epigenetics and human obesity
- (2014) S J van Dijk et al. INTERNATIONAL JOURNAL OF OBESITY
- Prevalence of Childhood and Adult Obesity in the United States, 2011-2012
- (2014) Cynthia L. Ogden et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- DNA methylation and body-mass index: a genome-wide analysis
- (2014) Katherine J Dick et al. LANCET
- Obesity-associated variants within FTO form long-range functional connections with IRX3
- (2014) Scott Smemo et al. NATURE
- Predicting DNA methylation level across human tissues
- (2014) Baoshan Ma et al. NUCLEIC ACIDS RESEARCH
- Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements
- (2013) Elin Grundberg et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The Impact of Obesity on US Mortality Levels: The Importance of Age and Cohort Factors in Population Estimates
- (2013) Ryan K. Masters et al. AMERICAN JOURNAL OF PUBLIC HEALTH
- Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study
- (2013) B. Hidalgo et al. DIABETES
- Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits
- (2013) Ann-Kristin Petersen et al. HUMAN MOLECULAR GENETICS
- Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes
- (2013) Xiaoling Zhang et al. HUMAN MOLECULAR GENETICS
- Common variants associated with plasma triglycerides and risk for coronary artery disease
- (2013) Ron Do et al. NATURE GENETICS
- Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
- (2013) Sonja I Berndt et al. NATURE GENETICS
- Discovery and refinement of loci associated with lipid levels
- (2013) Cristen J Willer et al. NATURE GENETICS
- Large-scale gene function analysis with the PANTHER classification system
- (2013) Huaiyu Mi et al. Nature Protocols
- Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss
- (2013) H. Yuan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The sva package for removing batch effects and other unwanted variation in high-throughput experiments
- (2012) Jeffrey T. Leek et al. BIOINFORMATICS
- Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease
- (2012) Caroline L Relton et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- BLUEPRINT to decode the epigenetic signature written in blood
- (2012) David Adams et al. NATURE BIOTECHNOLOGY
- New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
- (2012) Momoko Horikoshi et al. NATURE GENETICS
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
- (2012) NATURE GENETICS
- Large-scale association analysis identifies new risk loci for coronary artery disease
- (2012) Panos Deloukas et al. NATURE GENETICS
- A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
- (2012) Alisa K Manning et al. NATURE GENETICS
- Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
- (2012) Zari Dastani et al. PLoS Genetics
- AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
- (2011) Yu Li et al. Cell Metabolism
- A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
- (2011) D. M. Greenawalt et al. GENOME RESEARCH
- High density DNA methylation array with single CpG site resolution
- (2011) Marina Bibikova et al. GENOMICS
- Cohort Profile: The Lothian Birth Cohorts of 1921 and 1936
- (2011) I. J. Deary et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Ceramides as modulators of cellular and whole-body metabolism
- (2011) Benjamin T. Bikman et al. JOURNAL OF CLINICAL INVESTIGATION
- Optimally weighted Z-test is a powerful method for combining probabilities in meta-analysis
- (2011) D. V. ZAYKIN JOURNAL OF EVOLUTIONARY BIOLOGY
- A conditional knockout resource for the genome-wide study of mouse gene function
- (2011) William C. Skarnes et al. NATURE
- Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA
- (2011) Rudolf S. N. Fehrmann et al. PLoS Genetics
- Genetic control ofde novolipogenesis: role in diet-induced obesity
- (2010) Maggie S. Strable et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways
- (2010) N. Soranzo et al. DIABETES
- Intracellular Pathogen Sensor NOD2 Programs Macrophages to Trigger Notch1 Activation
- (2010) Kushagra Bansal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biological, clinical and population relevance of 95 loci for blood lipids
- (2010) Tanya M. Teslovich et al. NATURE
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
- (2010) Iris M Heid et al. NATURE GENETICS
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
- (2010) Elizabeth K Speliotes et al. NATURE GENETICS
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
- (2010) Josée Dupuis et al. NATURE GENETICS
- Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations
- (2010) Mathew J. Barber et al. PLoS One
- Epigenetic Epidemiology of Common Complex Disease: Prospects for Prediction, Prevention, and Treatment
- (2010) Caroline L. Relton et al. PLOS MEDICINE
- Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies
- (2009) Prospective Studies Collaboration LANCET
- Individuality and epigenetics in obesity
- (2009) J. Campión et al. Obesity Reviews
- Regulatory enzymes of mitochondrial β-oxidation as targets for treatment of the metabolic syndrome
- (2009) M. Schreurs et al. Obesity Reviews
- Common Regulatory Variation Impacts Gene Expression in a Cell Type-Dependent Manner
- (2009) A. S. Dimas et al. SCIENCE
- Mapping the Genetic Architecture of Gene Expression in Human Liver
- (2008) Eric E Schadt et al. PLOS BIOLOGY
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