Downregulation of SIRT1 signaling underlies hepatic autophagy impairment in glycogen storage disease type Ia

p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells

(2016) Atsushi Umemura et al.   CANCER CELL

Regulation of Liver Metabolism by Autophagy

(2016) Julio Madrigal-Matute et al.   GASTROENTEROLOGY

Induction of autophagy improves hepatic lipid metabolism in glucose-6-phosphatase deficiency

(2016) Benjamin L. Farah et al.   JOURNAL OF HEPATOLOGY

Profiling of the fetal and adult rat liver transcriptome and translatome reveals discordant regulation by the mechanistic target of rapamycin (mTOR)

(2015) Joan M. Boylan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications

(2015) Sujuan Guo et al.   Autophagy

Milk—A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation

(2015) Bodo Melnik   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagic flux determination in vivo and ex vivo

(2015) Lorena Esteban-Martínez et al.   METHODS

Metabolic Control of Autophagy

(2014) Lorenzo Galluzzi et al.   CELL

Peroxisome proliferator-activated receptor α activation attenuates the inflammatory response to protect the liver from acute failure by promoting the autophagy pathway

(2014) M Jiao et al.   Cell Death & Disease

The emerging role of acetylation in the regulation of autophagy

(2013) Ágnes Bánréti et al.   Autophagy

Sirtuins' modulation of autophagy

(2013) Fanny Ng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The return of the nucleus: transcriptional and epigenetic control of autophagy

(2013) Jens Füllgrabe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Novel insights into ChREBP regulation and function

(2013) Gaëlle Filhoulaud et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

(2012) Jose A. Martina et al.   Autophagy

Regulation of lipid stores and metabolism by lipophagy

(2012) K Liu et al.   CELL DEATH AND DIFFERENTIATION

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Prevention of hepatocellular adenoma and correction of metabolic abnormalities in murine glycogen storage disease type Ia by gene therapy

(2012) Young Mok Lee et al.   HEPATOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts

(2011) Eva Morán-Salvador et al.   FASEB JOURNAL

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

(2011) Yoshihiro Inami et al.   JOURNAL OF CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas

(2010) Elodie Mutel et al.   JOURNAL OF HEPATOLOGY

Complete Normalization of Hepatic G6PC Deficiency in Murine Glycogen Storage Disease Type Ia Using Gene Therapy

(2010) Wai Han Yiu et al.   MOLECULAR THERAPY

Glycogen storage disease type I and G6Pase-β deficiency: etiology and therapy

(2010) Janice Y. Chou et al.   Nature Reviews Endocrinology

mTOR phosphorylated at S2448 binds to raptor and rictor

(2009) M. Rosner et al.   AMINO ACIDS

TORC-Specific Phosphorylation of Mammalian Target of Rapamycin (mTOR): Phospho-Ser2481 Is a Marker for Intact mTOR Signaling Complex 2

(2009) J. Copp et al.   CANCER RESEARCH

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

Generation of mice with a conditional allele for G6pc

(2009) Wen-Tao Peng et al.   GENESIS

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL