GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway

IgA1 Glycosylation Is Heritable in Healthy Twins

(2016) Hannah J. Lomax-Browne et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

New developments in the genetics, pathogenesis, and therapy of IgA nephropathy

(2015) Riccardo Magistroni et al.   KIDNEY INTERNATIONAL

An epigenome-wide association study of total serum immunoglobulin E concentration

(2015) Liming Liang et al.   NATURE

A gene-based association method for mapping traits using reference transcriptome data

(2015) Eric R Gamazon et al.   NATURE GENETICS

Identification of new susceptibility loci for IgA nephropathy in Han Chinese

(2015) Ming Li et al.   Nature Communications

Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma

(2015) Bhairavi Swaminathan et al.   Nature Communications

Solving Glycosylation Disorders: Fundamental Approaches Reveal Complicated Pathways

(2014) Hudson H. Freeze et al.   AMERICAN JOURNAL OF HUMAN GENETICS

IgA measurements in over 12 000 Swedish twins reveal sex differential heritability and regulatory locus near CD30L

(2014) Alexander Viktorin et al.   HUMAN MOLECULAR GENETICS

Cytokines Alter IgA1O-Glycosylation by Dysregulating C1GalT1 and ST6GalNAc-II Enzymes

(2014) Hitoshi Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens

(2014) Krzysztof Kiryluk et al.   NATURE GENETICS

Accounting for eXentricities: Analysis of the X Chromosome in GWAS Reveals X-Linked Genes Implicated in Autoimmune Diseases

(2014) Diana Chang et al.   PLoS One

Immature truncated O-glycophenotype of cancer directly induces oncogenic features

(2014) Prakash Radhakrishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ChroMoS: an integrated web tool for SNP classification, prioritization and functional interpretation

(2013) M. Barenboim et al.   BIOINFORMATICS

Calculating statistical power in Mendelian randomization studies

(2013) Marie-Jo A Brion et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers

(2013) Gordan Lauc et al.   PLoS Genetics

Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers

(2012) Chen Yang et al.   IMMUNOGENETICS

Autoantibodies Targeting Galactose-Deficient IgA1 Associate with Progression of IgA Nephropathy

(2012) F. Berthoux et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The level of galactose-deficient IgA1 in the sera of patients with IgA nephropathy is associated with disease progression

(2012) Na Zhao et al.   KIDNEY INTERNATIONAL

Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

(2012) Benjamin P Fairfax et al.   NATURE GENETICS

Genetically Distinct Subsets within ANCA-Associated Vasculitis

(2012) Paul A. Lyons et al.   NEW ENGLAND JOURNAL OF MEDICINE

FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs

(2012) Simon G. Coetzee et al.   NUCLEIC ACIDS RESEARCH

Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis

(2012) Krzysztof Kiryluk et al.   PLoS Genetics

Discovering and visualizing indirect associations between biomedical concepts

(2011) Y. Tsuruoka et al.   BIOINFORMATICS

Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice

(2011) Jianxin Fu et al.   JOURNAL OF CLINICAL INVESTIGATION

Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch–Schönlein purpura nephritis

(2011) Krzysztof Kiryluk et al.   KIDNEY INTERNATIONAL

Genome-wide association study identifies susceptibility loci for IgA nephropathy

(2011) Ali G Gharavi et al.   NATURE GENETICS

PINA v2.0: mining interactome modules

(2011) Mark J. Cowley et al.   NUCLEIC ACIDS RESEARCH

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

(2011) Elizabeth J. Rossin et al.   PLoS Genetics

A spectral graph approach to discovering genetic ancestry

(2010) Ann B. Lee et al.   Annals of Applied Statistics

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency

(2010) Ricardo C Ferreira et al.   NATURE GENETICS

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Targeted capture and massively parallel sequencing of 12 human exomes

(2009) Sarah B. Ng et al.   NATURE

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

(2009) Soumya Raychaudhuri et al.   PLoS Genetics

SNPnexus: a web database for functional annotation of newly discovered and public domain single nucleotide polymorphisms

(2008) C. Chelala et al.   BIOINFORMATICS

e-LiSe--an online tool for finding needles in the '(Medline) haystack'

(2008) A. Gladki et al.   BIOINFORMATICS

Estimation of significance thresholds for genomewide association scans

(2008) Frank Dudbridge et al.   GENETIC EPIDEMIOLOGY

Aberrant IgA1 Glycosylation Is Inherited in Familial and Sporadic IgA Nephropathy

(2008) A. G. Gharavi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus

(2008) Stephan Weidinger et al.   PLoS Genetics