Diverse type 2 diabetes genetic risk factors functionally converge in a phenotype-focused gene network

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

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Candidate gene prioritization with Endeavour

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Part mutual information for quantifying direct associations in networks

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The clustering of functionally related genes contributes to CNV-mediated disease

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Understanding multicellular function and disease with human tissue-specific networks

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The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors

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Bias tradeoffs in the creation and analysis of protein–protein interaction networks

(2014) Jesse Gillis et al.   Journal of Proteomics

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

(2014) Valgerdur Steinthorsdottir et al.   NATURE GENETICS

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

(2014) Lorenzo Pasquali et al.   NATURE GENETICS

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

(2014) Jason Flannick et al.   NATURE GENETICS

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

(2014) Anubha Mahajan et al.   NATURE GENETICS

Conditional mutual inclusive information enables accurate quantification of associations in gene regulatory networks

(2014) Xiujun Zhang et al.   NUCLEIC ACIDS RESEARCH

Unbiased Functional Clustering of Gene Variants with a Phenotypic-Linkage Network

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Phenotype Ontologies and Cross-Species Analysis for Translational Research

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Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome

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Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future

(2013) Steven E Kahn et al.   LANCET

The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse

(2013) Judith A. Blake et al.   NUCLEIC ACIDS RESEARCH

The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data

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Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained

(2013) Ying Wu et al.   PLoS Genetics

Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies

(2012) Seunggeun Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

RETRACTED ARTICLE: Candidate gene prioritization

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Diabetes in numbers

(2012) Tony Scully   NATURE

An integrated map of genetic variation from 1,092 human genomes

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

“Guilt by Association” Is the Exception Rather Than the Rule in Gene Networks

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Prioritizing candidate disease genes by network-based boosting of genome-wide association data

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One Hundred Years of Migraine Research: Major Clinical and Scientific Observations From 1910 to 2010

(2011) Peer C. Tfelt-Hansen et al.   HEADACHE

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

(2011) Jaspal S Kooner et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

(2011) Yoon Shin Cho et al.   NATURE GENETICS

InterPro in 2011: new developments in the family and domain prediction database

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The Impact of Multifunctional Genes on "Guilt by Association" Analysis

(2011) Jesse Gillis et al.   PLoS One

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

(2011) Elizabeth J. Rossin et al.   PLoS Genetics

A guide to web tools to prioritize candidate genes

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A global map of human gene expression

(2010) Margus Lukk et al.   NATURE BIOTECHNOLOGY

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

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The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

(2010) D. Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Reactome: a database of reactions, pathways and biological processes

(2010) D. Croft et al.   NUCLEIC ACIDS RESEARCH

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

(2010) Ayellet V. Segrè et al.   PLoS Genetics

KEGG for representation and analysis of molecular networks involving diseases and drugs

(2009) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Fast unfolding of communities in large networks

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