期刊
GENOME MEDICINE
卷 9, 期 -, 页码 -出版社
BIOMED CENTRAL LTD
DOI: 10.1186/s13073-017-0461-x
关键词
Antibiotic resistance; ESBL; Escherichia coli; MRSA; Next-generation sequencing; Staphylococcus aureus
资金
- Intramural Research Program of the National Institute of Allergy and Infectious Diseases, U.S. National Institutes of Health
Next-generation sequencing is increasingly being used to monitor current and historic events related to the emergence and spread of antimicrobial resistance. In a recent publication, researchers analyzed the rise of methicillin-resistant Staphylococcus aureus in the 1960s, emphasizing that adaptations conferring antibiotic resistance might pre-date the introduction of novel antibiotic derivatives. Other researchers have evaluated the role of transmission within a healthcare network, using the example of extended-spectrum beta-lactamase-resistant Escherichia coli.
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