标题
Big Bang Tumor Growth and Clonal Evolution
作者
关键词
-
出版物
Cold Spring Harbor Perspectives in Medicine
Volume 8, Issue 5, Pages a028381
出版商
Cold Spring Harbor Laboratory
发表日期
2017-07-15
DOI
10.1101/cshperspect.a028381
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Between-region genetic divergence reflects the mode and tempo of tumor evolution
- (2017) Ruping Sun et al. NATURE GENETICS
- Order Matters: The Order of Somatic Mutations Influences Cancer Evolution
- (2017) David G. Kent et al. Cold Spring Harbor Perspectives in Medicine
- Understanding Intratumoral Heterogeneity: Lessons from the Analysis of At-Risk Tissue and Premalignant Lesions in the Colon
- (2016) C. K. Sievers et al. Cancer Prevention Research
- Multi-organ Mapping of Cancer Risk
- (2016) Liqin Zhu et al. CELL
- Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates
- (2016) Chelsie K Sievers et al. GUT
- New paradigms in clonal evolution: punctuated equilibrium in cancer
- (2016) William CH Cross et al. JOURNAL OF PATHOLOGY
- Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer
- (2016) Yuka Suzuki et al. Molecular Oncology
- A 17-gene stemness score for rapid determination of risk in acute leukaemia
- (2016) Stanley W. K. Ng et al. NATURE
- A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
- (2016) Faiyaz Notta et al. NATURE
- Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer
- (2016) Andrew McPherson et al. NATURE GENETICS
- Punctuated copy number evolution and clonal stasis in triple-negative breast cancer
- (2016) Ruli Gao et al. NATURE GENETICS
- Identification of neutral tumor evolution across cancer types
- (2016) Marc J Williams et al. NATURE GENETICS
- Constrained positive selection on cancer mutations in normal skin
- (2016) Iñigo Martincorena et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
- (2016) N. McGranahan et al. SCIENCE
- Kataegis Expression Signature in Breast Cancer Is Associated with Late Onset, Better Prognosis, and Higher HER2 Levels
- (2016) Matteo D’Antonio et al. Cell Reports
- Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma
- (2016) Marios Giannakis et al. Cell Reports
- Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution
- (2016) Ivana Bozic et al. PLoS Computational Biology
- Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution
- (2016) Ryutaro Uchi et al. PLoS Genetics
- A Critical Examination of the "Bad Luck" Explanation of Cancer Risk
- (2015) A. I. Rozhok et al. Cancer Prevention Research
- Subclonal Genomic Architectures of Primary and Metastatic Colorectal Cancer Based on Intratumoral Genetic Heterogeneity
- (2015) T.-M. Kim et al. CLINICAL CANCER RESEARCH
- Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale
- (2015) Louise J Barber et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution
- (2015) Hoon Kim et al. GENOME RESEARCH
- Many private mutations originate from the first few divisions of a human colorectal adenoma
- (2015) Haeyoun Kang et al. JOURNAL OF PATHOLOGY
- Chromothripsis from DNA damage in micronuclei
- (2015) Cheng-Zhong Zhang et al. NATURE
- A Big Bang model of human colorectal tumor growth
- (2015) Andrea Sottoriva et al. NATURE GENETICS
- Subclonal diversification of primary breast cancer revealed by multiregion sequencing
- (2015) Lucy R Yates et al. NATURE MEDICINE
- Effect of Mutation Order on Myeloproliferative Neoplasms
- (2015) Christina A. Ortmann et al. NEW ENGLAND JOURNAL OF MEDICINE
- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
- (2015) Dung T. Le et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Path to Cancer — Three Strikes and You're Out
- (2015) Bert Vogelstein et al. NEW ENGLAND JOURNAL OF MEDICINE
- Peto's paradox and human cancers
- (2015) Robert Noble et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution
- (2015) Shaoping Ling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Variation in cancer risk among tissues can be explained by the number of stem cell divisions
- (2015) C. Tomasetti et al. SCIENCE
- Evolutionary Determinants of Cancer
- (2015) M. Greaves Cancer Discovery
- Cell-lineage heterogeneity and driver mutation recurrence in pre-invasive breast neoplasia
- (2015) Ziming Weng et al. Genome Medicine
- Mutant cohesin drives chromosomal instability in early colorectal adenomas
- (2014) Francesco Cucco et al. HUMAN MOLECULAR GENETICS
- Clonal evolution in breast cancer revealed by single nucleus genome sequencing
- (2014) Yong Wang et al. NATURE
- Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
- (2014) Allison S. Cleary et al. NATURE
- Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
- (2014) Liran I. Shlush et al. NATURE
- Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity
- (2014) Andriy Marusyk et al. NATURE
- Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis
- (2014) Jamie M J Weaver et al. NATURE GENETICS
- Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
- (2014) Marco Gerlinger et al. NATURE GENETICS
- Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
- (2014) Alexandra Snyder et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
- (2014) Giulio Genovese et al. NEW ENGLAND JOURNAL OF MEDICINE
- Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
- (2014) J. Zhang et al. SCIENCE
- Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
- (2014) E. C. de Bruin et al. SCIENCE
- High intratumor genetic heterogeneity is related to worse outcome in patients with head and neck squamous cell carcinoma
- (2013) Edmund A. Mroz et al. CANCER
- Punctuated Evolution of Prostate Cancer Genomes
- (2013) Sylvan C. Baca et al. CELL
- Criteria for Inference of Chromothripsis in Cancer Genomes
- (2013) Jan O. Korbel et al. CELL
- Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling
- (2013) Ali Bashashati et al. JOURNAL OF PATHOLOGY
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Impact of deleterious passenger mutations on cancer progression
- (2013) C. D. McFarland et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
- (2013) A. Sottoriva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation
- (2013) L. Vermeulen et al. SCIENCE
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- AID/APOBEC cytosine deaminase induces genome-wide kataegis
- (2012) Artem G Lada et al. Biology Direct
- Single-Molecule Genomic Data Delineate Patient-Specific Tumor Profiles and Cancer Stem Cell Organization
- (2012) A. Sottoriva et al. CANCER RESEARCH
- Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
- (2012) Tobias Rausch et al. CELL
- The Life History of 21 Breast Cancers
- (2012) Serena Nik-Zainal et al. CELL
- An evolutionary explanation for the presence of cancer nonstem cells in neoplasms
- (2012) Kathleen Sprouffske et al. Evolutionary Applications
- Clonal evolution in cancer
- (2012) Mel Greaves et al. NATURE
- Evolution of the cancer genome
- (2012) Lucy R. Yates et al. NATURE REVIEWS GENETICS
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma
- (2012) Edmund A. Mroz et al. ORAL ONCOLOGY
- Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
- (2011) Philip J. Stephens et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Prognostic and predictive impact of DNA mismatch repair in the management of colorectal cancer
- (2011) Frank A Sinicrope et al. Future Oncology
- Intratumor Heterogeneity in Evolutionary Models of Tumor Progression
- (2011) Rick Durrett et al. GENETICS
- Spatial structure increases the waiting time for cancer
- (2011) Erik A Martens et al. NEW JOURNAL OF PHYSICS
- High DNA Methylation Pattern Intratumoral Diversity Implies Weak Selection in Many Human Colorectal Cancers
- (2011) Kimberly D. Siegmund et al. PLoS One
- Distant metastasis occurs late during the genetic evolution of pancreatic cancer
- (2010) Shinichi Yachida et al. NATURE
- Effective population size and patterns of molecular evolution and variation
- (2009) Brian Charlesworth NATURE REVIEWS GENETICS
- Genomic instability demonstrates similarity between DCIS and invasive carcinomas
- (2008) Christopher M. Heaphy et al. BREAST CANCER RESEARCH AND TREATMENT
- Is Breast Tumor Progression Really Linear?
- (2008) K. Polyak CLINICAL CANCER RESEARCH
- Ductal Carcinoma In situ and the Emergence of Diversity during Breast Cancer Evolution
- (2008) D. C. Allred et al. CLINICAL CANCER RESEARCH
- Clonal Interference, Multiple Mutations and Adaptation in Large Asexual Populations
- (2008) C. A. Fogle et al. GENETICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started