Selective Cell Penetrating Peptide-Functionalized Polymersomes Mediate Efficient and Targeted Delivery of Methotrexate Disodium to Human Lung Cancer In Vivo

Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance

(2017) Alena Braunová et al.   JOURNAL OF CONTROLLED RELEASE

Bioreducible branched poly(modified nona-arginine) cell-penetrating peptide as a novel gene delivery platform

(2017) Jisang Yoo et al.   JOURNAL OF CONTROLLED RELEASE

ATN-161 Peptide Functionalized Reversibly Cross-Linked Polymersomes Mediate Targeted Doxorubicin Delivery into Melanoma-Bearing C57BL/6 Mice

(2017) Ning Zhang et al.   MOLECULAR PHARMACEUTICS

Polymer Prodrug-Based Nanoreactors Activated by Tumor Acidity for Orchestrated Oxidation/Chemotherapy

(2017) Junjie Li et al.   NANO LETTERS

Overcoming multidrug resistance using folate receptor-targeted and pH-responsive polymeric nanogels containing covalently entrapped doxorubicin

(2017) Y. Chen et al.   Nanoscale

Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration

(2016) Hong-Jun Li et al.   ACS Nano

Thiolation and Cell-Penetrating Peptide Surface Functionalization of Porous Silicon Nanoparticles for Oral Delivery of Insulin

(2016) Neha Shrestha et al.   ADVANCED FUNCTIONAL MATERIALS

Efficient and Targeted Suppression of Human Lung Tumor Xenografts in Mice with Methotrexate Sodium Encapsulated in All-Function-in-One Chimeric Polymersomes

(2016) Weijing Yang et al.   ADVANCED MATERIALS

Robust, tumor-homing and redox-sensitive polymersomal doxorubicin: A superior alternative to Doxil and Caelyx?

(2016) Yan Zou et al.   JOURNAL OF CONTROLLED RELEASE

Enzyme-triggered, cell penetrating peptide-mediated delivery of anti-tumor agents

(2016) Huining He et al.   JOURNAL OF CONTROLLED RELEASE

Spontaneous Internalization of Cell Penetrating Peptide-Modified Nanowires into Primary Neurons

(2016) Jae-Hyun Lee et al.   NANO LETTERS

Preventing and Managing Toxicities of High-Dose Methotrexate

(2016) S. C. Howard et al.   ONCOLOGIST

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

(2016) Hong-Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methotrexate-Loaded Four-Arm Star Amphiphilic Block Copolymer Elicits CD8+ T Cell Response against a Highly Aggressive and Metastatic Experimental Lymphoma

(2015) Sumit Kumar Hira et al.   ACS Applied Materials & Interfaces

Surface engineered polymeric nanocarriers mediate the delivery of transferrin–methotrexate conjugates for an improved understanding of brain cancer

(2015) Atul Jain et al.   Acta Biomaterialia

Peptide Assembly Integration of Fibroblast-Targeting and Cell-Penetration Features for Enhanced Antitumor Drug Delivery

(2015) Tianjiao Ji et al.   ADVANCED MATERIALS

Hydrophobically Modified Keratin Vesicles for GSH-Responsive Intracellular Drug Release

(2015) Manuela Curcio et al.   BIOCONJUGATE CHEMISTRY

Antibody fragment-conjugated polymeric micelles incorporating platinum drugs for targeted therapy of pancreatic cancer

(2015) Jooyeon Ahn et al.   BIOMATERIALS

Matrix metalloproteinase-sensitive size-shrinkable nanoparticles for deep tumor penetration and pH triggered doxorubicin release

(2015) Shaobo Ruan et al.   BIOMATERIALS

Tumor homing cell penetrating peptide decorated nanoparticles used for enhancing tumor targeting delivery and therapy

(2015) Huile Gao et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A pH-responsive cell-penetrating peptide-modified liposomes with active recognizing of integrin α v β 3 for the treatment of melanoma

(2015) Kairong Shi et al.   JOURNAL OF CONTROLLED RELEASE

Efficacious delivery of protein drugs to prostate cancer cells by PSMA-targeted pH-responsive chimaeric polymersomes

(2015) Xiang Li et al.   JOURNAL OF CONTROLLED RELEASE

A comparative study of folate receptor-targeted doxorubicin delivery systems: Dosing regimens and therapeutic index

(2015) Anna Scomparin et al.   JOURNAL OF CONTROLLED RELEASE

Reversible Activation of a Cell-Penetrating Peptide in a Membrane Environment

(2015) Denise K. Schach et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Methotrexate-Conjugated PEGylated Dendrimers Show Differential Patterns of Deposition and Activity in Tumor-Burdened Lymph Nodes after Intravenous and Subcutaneous Administration in Rats

(2015) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

PEGylated liposomes with NGR ligand and heat-activable cell-penetrating peptide–doxorubicin conjugate for tumor-specific therapy

(2014) Yanfang Yang et al.   BIOMATERIALS

Methotrexate-loaded PLGA nanobubbles for ultrasound imaging and Synergistic Targeted therapy of residual tumor during HIFU ablation

(2014) Xuemei Zhang et al.   BIOMATERIALS

Cell-penetrating peptides meditated encapsulation of protein therapeutics into intact red blood cells and its application

(2014) Huining He et al.   JOURNAL OF CONTROLLED RELEASE

Multifunctional Tumor pH-Sensitive Self-Assembled Nanoparticles for Bimodal Imaging and Treatment of Resistant Heterogeneous Tumors

(2014) Daishun Ling et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Parameters of siRNA–Cell Penetrating Peptide Nanocomplexes for Efficient Cellular Delivery

(2013) Alexander H. van Asbeck et al.   ACS Nano

pH-sensitive pullulan-based nanoparticle carrier of methotrexate and combretastatin A4 for the combination therapy against hepatocellular carcinoma

(2013) Yinsong Wang et al.   BIOMATERIALS

Peptides as Targeting Elements and Tissue Penetration Devices for Nanoparticles

(2012) Erkki Ruoslahti   ADVANCED MATERIALS

Aptamer-Functionalized, Ultra-Small, Monodisperse Silica Nanoconjugates for Targeted Dual-Modal Imaging of Lymph Nodes with Metastatic Tumors

(2012) Li Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth

(2012) Zhaohui Wang et al.   BIOMATERIALS

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

TAT Peptide-Functionalized Gold Nanostars: Enhanced Intracellular Delivery and Efficient NIR Photothermal Therapy Using Ultralow Irradiance

(2012) Hsiangkuo Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acid-Active Cell-Penetrating Peptides for in Vivo Tumor-Targeted Drug Delivery

(2012) Erlei Jin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-penetrating peptides: breaking through to the other side

(2012) Erez Koren et al.   TRENDS IN MOLECULAR MEDICINE

Tumour lineage-homing cell-penetrating peptides as anticancer molecular delivery systems

(2012) Eisaku Kondo et al.   Nature Communications

Synthesis, pharmacoscintigraphic evaluation and antitumor efficacy of methotrexate-loaded, folate-conjugated, stealth albumin nanoparticles

(2011) Sanyog Jain et al.   Nanomedicine

Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials

(2011) Feng Zhao et al.   Small

Glucarpidase, Leucovorin, and Thymidine for High-Dose Methotrexate-Induced Renal Dysfunction: Clinical and Pharmacologic Factors Affecting Outcome

(2010) Brigitte C. Widemann et al.   JOURNAL OF CLINICAL ONCOLOGY

Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: A case–control study

(2010) David Laharie et al.   JOURNAL OF HEPATOLOGY

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

(2010) K. N. Sugahara et al.   SCIENCE