Article
Pharmacology & Pharmacy
Zehua Han, Minjie Gao, Zhihua Wang, Lichao Peng, Yanbao Zhao, Lei Sun
Summary: In this study, gold nanorods were encapsulated in mesoporous polydopamine shells to create an ideal photothermal composite and drug delivery carrier with excellent photothermal properties and biocompatibility. Further sealing of the pore channels using polyethyleneimine resulted in a pH-/NIR-responsive nanocarrier with high drug loading capacities. The carrier demonstrated significant anticancer effects in vitro, showing promise as a nanoplatform for multifunctional cancer therapy in the future.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Zhiwei Zhang, Jingjing Xiang, Lijiao Guan, Pu Chen, Changzhong Li, Chunlei Guo, Yan Hu, Saipeng Huang, Lintao Cai, Ping Gong
Summary: By designing and synthesizing a pH-activated photothermal sensitizer IR-PE, it is possible to trigger the lysosomal dysfunction-mediated Fenton pathway under near-infrared light irradiation, thereby inducing ferroptosis and improving antitumor efficacy while mitigating systemic side effects.
Article
Pharmacology & Pharmacy
Xiaowei Wang, Yufen Li, Ji Li, Yaxuan Gu, Lihong Sang, Dongkai Wang
Summary: The combination of multiple therapies can significantly improve the treatment efficiency of malignant tumors, and the combination of AS-IV and ICG enhances the anti-tumor effect. Liposomes co-loaded with AS-IV and ICG for chemo-photothermal therapy of breast cancer show promising results in vitro and in vivo, providing a safe and efficient strategy for synergistic combination therapy.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Xinli Li, Mengru Chen, Yanbao Zhao, Lei Sun
Summary: S-S bond-doped porous silica nanoparticles with CuS nanocores were prepared as drug carriers for chemical-photothermal synergistic therapy and redox/pH/light triple-response drug release. The synthesized carriers have dendritic pore structure with particle size of about 100 nm and showed good biocompatibility. The introduction of CuS nanocores provided the system with a good photothermal therapy function.
BIOCHEMICAL ENGINEERING JOURNAL
(2021)
Review
Chemistry, Physical
Yi Yang, Haiyan Tan, Bei Cheng, Jiajie Fan, Jiaguo Yu, Wingkei Ho
Summary: Expanding light absorption to the near-infrared region is crucial in photocatalysis; NIR-responsive photocatalysts can utilize diffuse solar energy; This study summarizes recent progress and different photocatalytic systems.
Review
Pharmacology & Pharmacy
Yuseon Shin, Patihul Husni, Kioh Kang, Dayoon Lee, Sehwa Lee, Eunseong Lee, Yuseok Youn, Kyungtaek Oh
Summary: The combination of nanotechnology and chemotherapy has led to more effective drug design through the development of nanomaterial-based drug delivery systems, offering precise control over the release of therapeutics. Among these systems, photo-triggered and pH-induced delivery methods have been widely studied and are effective in targeting solid tumors.
Article
Pharmacology & Pharmacy
Huai-An Chen, Yu-Jen Lu, Banendu Sunder Dash, Yin-Kai Chao, Jyh-Ping Chen
Summary: Combination chemo-photothermal therapy using HA/PMNPc nanoparticles can effectively treat cancer by reducing the dose of chemotherapeutic drugs and inducing cell death through heat generation. The nanoparticles exhibit targeted delivery, pH-sensitive drug release, and hyperthermia effects, resulting in higher cytotoxicity and apoptosis in cancer cells. In vivo studies demonstrate that the treatment modality inhibits tumor growth and increases survival time in mice.
Article
Materials Science, Multidisciplinary
Yilin Guo, Na Liu, Qiang Cao, Xu Cheng, Peng Zhang, Qingqing Guan, Wei Zheng, Guomei He, Jiangxi Chen
Summary: Near-infrared-responsive liquid crystal elastomers are interesting intelligent deformable materials that have been extensively studied in various fields. However, the availability of organic near-infrared substances for use in these elastomers is still limited. In this study, a near-infrared light-absorbing diol was synthesized, and a polyurethane-based liquid crystal elastomer was successfully developed, demonstrating excellent deformation ability.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Kai-fei Wang, Yi-ping Mu, Shu Wang, Yin-xue Song, Jing Xu, Xiao-hui Li, Rui-tao Wang
Summary: Researchers have successfully developed an erythrocyte membrane-camouflaged metal-organic framework (ICG@RB-MOF) loaded with indocyanine green (ICG) for photothermal therapy of pancreatic cancer. The release of ICG in acidic tumor environments and the erythrocyte membrane surface modification significantly enhance the tumor-targeting ability of ICG@RB-MOF. In vitro and in vivo experiments have demonstrated the significant therapeutic effect of prepared ICG@RB-MOF on pancreatic cancer.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Chemistry, Applied
Chongchong Liu, Panping Yang, Jingguo Li, Shaokui Cao, Jun Shi
Summary: In this study, a remotely multi-responsive chitosan hydrogel was prepared with near-infrared (NIR) responsiveness, pH response, and thermal responsiveness. It showed notable NIR-triggered photo-thermal effect and remotely controllable drug delivery properties.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Multidisciplinary
Kaili Yang, Weijun Xiu, Yuqing Li, Dou Wang, Qirui Wen, Lihui Yuwen, Xiao Li, Zhaowei Yin, Bin Liang, Lianhui Wang
Summary: In this study, a near-infrared responsive 2D nanozyme was developed for efficient treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. The nanozyme exhibited effective antibacterial properties against MRSA through catalytic and photothermal effects. The results showed that the nanozyme had high bactericidal activity against MRSA under near-infrared light irradiation and promoted wound healing.
Article
Engineering, Environmental
Xingxing Chen, Ruyue Wang, Chenhui Cui, Le An, Qiang Zhang, Yilong Cheng, Yanfeng Zhang
Summary: Fabrication of covalent adaptable networks with the combination of intrinsic photothermal responsiveness, NIR-triggered welding, multiple-shape memory, and selective shape memory recovery remains a challenge. The developed PUOUs show strong photothermal effect and can achieve rapid welding through the dynamic exchange of oxime-carbamate bonds induced by near-infrared laser. With two independent glass transition temperatures, PUOUs exhibit triple shape memory property and selective shape memory recovery in the region subjected to NIR irradiation.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Biotechnology & Applied Microbiology
Xiaoyang Guo, Jia Liu, Lingdong Jiang, Wanjun Gong, Huixia Wu, Qianjun He
Summary: The study developed a Pd-Su nanomedicine with high loading capacity of Su, high near-infrared photothermal conversion efficiency, and NIR-controlled H2S release. The combination of photothermal therapy and H2S gas therapy showed a strong synergistic effect in inhibiting tumor growth by inhibiting heat shock response. Additionally, the intratumoral accumulation of the nanomedicine enabled dual-mode imaging-guided tumor treatment.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Dong An, Jianye Fu, Bin Zhang, Ni Xie, Guohui Nie, Hans Agren, Meng Qiu, Han Zhang
Summary: Non-invasive cancer photothermal therapy (PTT) shows potential as a replacement for traditional cancer treatments, with recent developments focusing on NIR-II PTT and the use of inorganic 2D nanomaterials as photothermal agents (PTAs) to enhance efficiency. Strategies integrating NIR-II responsive PTT with other treatment approaches are promising for advancing cancer therapy.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Manlin Qi, Xuan Ren, Wen Li, Yue Sun, Xiaolin Sun, Chunyan Li, Siyao Yu, Lin Xu, Yanmin Zhou, Shuyan Song, Biao Dong, Lin Wang
Summary: This study successfully developed a near-infrared light triggered nanoplatform with dual functions of antibacterial and anti-inflammatory effects. It can effectively treat periodontal disease by killing bacteria and dispersing biofilms, as well as inhibiting inflammation through the release of gas molecules. The nanoplatform shows promising therapeutic potential for periodontal diseases and other refractory infections in deep tissues.
Article
Materials Science, Multidisciplinary
Guangbao Yang, Anivind Kaur Bindra, Soo Zeng Fiona Phua, Jiawei Liu, Hongwei Wu, Dongdong Wang, Cheng Qian, Guofeng Liu, Yanli Zhao
Summary: In this study, a nanomaterial UiO-AZB/HC-TPZ was developed that can generate singlet oxygen and induce tumor hypoxia under light irradiation, achieving a combination therapy of PDT and hypoxia-activated chemotherapy.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Hong Zhang, Bin Song, Weiwei Zhang, Bowen An, Lin Fu, Songtao Lu, Yingwen Cheng, Qianwang Chen, Ke Lu
Summary: In this study, core-shell structured composite matrixes were used to achieve nearly fully reversible cycling of sulfur cathodes for Na-S batteries. The bidirectional tandem electrocatalysis enabled successive reversible conversion of both long- and short-chain polysulfides, while Fe2O3 and redox-active Fe(CN)(6)(4-)-doped polypyrrole shell facilitated specific conversions. The electrochemically reactive Na2S could be readily charged back to sulfur, and stable cycling of a Na-S pouch cell with high reversible capacity was demonstrated.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Hao Huang, Shi Chen, Peng Jiang, Yang Yang, Changlai Wang, Wei Zheng, Zhiyu Cheng, Minxue Huang, Lin Hu, Qianwang Chen
Summary: Theoretical calculations demonstrate that lithium embedded in N, O-doped graphene is an effective electrocatalytic active center for CO2 reduction and oxygen reduction reactions. This is due to the s-p orbital hybridization between the empty 2p orbital of lithium and the orbitals of coordinated atoms. Experimental results show that a carbon-based catalyst with well-anchored lithium atoms coordinated to N, O substituents exhibits exceptional performance in CO2 reduction and oxygen reduction reactions in acidic media.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Ge Yao, Zhiqiang Li, Yuhang Zhang, Yue Xiao, Lingzhi Wei, Helin Niu, Qianwang Chen, Yang Yang, Fangcai Zheng
Summary: In this study, a flexible carbon film implanted with single-atomic Zn-N-2 moiety was constructed as an efficient sulfur host material to improve the redox kinetics and electrical conductivity of sulfur cathode in room-temperature sodium-sulfur batteries.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Dongdong Wang, Lei Zhang, Changlai Wang, Zhiyu Cheng, Wei Zheng, Pengping Xu, Qianwang Chen, Yanli Zhao
Summary: Researchers develop a facile missing-linker-confined coordination strategy to fabricate two self-assembled nanozymes: conventional nanozyme (NE) and single-atomic nanozyme (SAE). They consist of Pt nanoparticles and single Pt atoms as active catalytic sites anchored in metal-organic frameworks (MOFs) with encapsulated photosensitizers for catalase-mimicking enhanced photodynamic therapy. Compared to a Pt nanoparticle-based conventional nanozyme, a Pt single-atomic nanozyme shows enhanced catalase-mimicking activity in generating oxygen for overcoming tumor hypoxia, exhibiting more efficient reactive oxygen species generation and higher tumor inhibition rate.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Engineering, Environmental
Qianqian Zhou, Peidong Hong, Xu Shi, Yulian Li, Ke Yao, Wanqi Zhang, Chengming Wang, Junyong He, Kaisheng Zhang, Lingtao Kong
Summary: In this study, a novel Cu2O/Cu@MXene composite with a nanoconfinement structure was designed to effectively activate peroxymonosulfate (PMS) for the degradation of tetracycline (TC). Results showed that the MXene could fix the Cu2O/Cu nanoparticles and suppress their agglomeration, leading to a removal efficiency of 99.14% for TC within 30 minutes. The outstanding catalytic performance was attributed to the promotion of TC adsorption and electron transmission by the MXene. Furthermore, the degradation efficiency of TC remained over 82% after five cycles, and two specific degradation pathways were proposed based on the LC-MS analysis. This study provides valuable insights for suppressing the agglomeration of nanoparticles and expands the application of MXene materials in environmental remediation.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Jinwei Tu, Huigang Tong, Peichen Wang, Dongdong Wang, Yang Yang, Xiangfu Meng, Lin Hu, Hui Wang, Qianwang Chen
Summary: Due to the deficiency and uneven distribution of lithium resources, potassium-ion batteries have attracted more attention as viable alternatives to lithium-ion batteries. This study shows that the unique anti-spinel structure of magnetite can serve as K+ storage sites, and carbon-coated Fe3O4@C nanoparticles exhibit high reversible capacity and hyper stable cycling performance in potassium-ion batteries.
Article
Multidisciplinary Sciences
Dongdong Wang, Jiawei Liu, Changlai Wang, Weiyun Zhang, Guangbao Yang, Yun Chen, Xiaodong Zhang, Yinglong Wu, Long Gu, Hongzhong Chen, Wei Yuan, Xiaokai Chen, Guofeng Liu, Bin Gao, Qianwang Chen, Yanli Zhao
Summary: Cancer immunotherapy is revolutionizing oncology and the combination of nanotechnology and immunotherapy provides an opportunity to enhance antitumor immune response. This study presents a mitochondria-targeting nanoplatform, MiBaMc, which consists of Prussian blue nanoparticles derived from bacteria and shows enhanced tumor inhibition in mouse models. The findings demonstrate the potential of targeted nanoparticles in boosting antitumor immunity.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Dong Wang, Shuo Shi, Yanyun Mao, Leqi Lei, Shaohai Fu, Jinlian Hu
Summary: A novel dual-network design strategy is proposed to prepare a high-performance cellulosic composite bioplastic metafilm with exceptional mechanical toughness, flame retardance, and solvent resistance. The metafilm exhibits a higher maximum usage temperature, lower thermal expansion coefficient, good biocompatibility, and natural biodegradation, making it a competitive substitute for plastics.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Engineering, Environmental
Zhen He, Qiaohui Duan, Lingwen Liao, Chengming Wang
Summary: Jagged Au-Pt bimetallic nanowires with abundant twin boundaries have been synthesized, and the lattice strain and electronic structures of Pt in the twin-rich nanowires have been tuned, resulting in the modulation of alcohol oxidation reaction (AOR) activities. The AuPt3 nanowires exhibit the highest mass activity for ethanol and methanol oxidation reactions, surpassing other nanowires and commercial Pt/C catalysts. The structure-activity correlation for AOR follows a volcano-shaped curve with increasing Pt ratios. This work provides a simple yet effective method to synthesize twin-rich bimetallic nanostructures with controlled lattice strain and illustrates their structure-dependent properties.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Yafei Qu, Wei Zheng, Peichen Wang, Hao Huang, Minxue Huang, Lin Hu, Hui Wang, Qianwang Chen
Summary: Electrochemical carbon dioxide reduction reaction (CO2RR) is an effective method to capture and convert CO2 into valuable chemicals and fuels, reducing CO2 emissions. Copper-based catalysts have shown excellent performance in converting CO2 into multi-carbon compounds and hydrocarbons. However, their selectivity towards coupling products is poor.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Zhen He, Qiaohui Duan, Chengming Wang, Lingwen Liao
Summary: Penta-twinned Pd nanowires with abundant high-energy atomic steps have been synthesized and they exhibit superior catalytic activity for ethanol and ethylene glycol oxidation reactions. These stepped Pd nanowires show enhanced catalytic performance and stability compared to commercial Pd/C. The mass activities of stepped Pd nanowires for EOR and EGOR are 6.38 and 7.98 A mg(Pd)(-1), respectively, which are 3.1 and 2.6 times higher than Pd nanowires enclosed by (100) facets.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Multidisciplinary Sciences
Yinglong Wu, Lihe Sun, Xiaokai Chen, Jiawei Liu, Juan Ouyang, Xiaodong Zhang, Yi Guo, Yun Chen, Wei Yuan, Dongdong Wang, Ting He, Fang Zeng, Hongzhong Chen, Shuizhu Wu, Yanli Zhao
Summary: The authors address the challenges in using organic small-molecule contrast agents for multispectral optoacoustic imaging by constructing water-dispersible supramolecular optoacoustic assemblies based on cucurbit[8]uril. The constructed assemblies show enhanced optoacoustic performance due to increased absorption and decreased fluorescence. The formulated assemblies can effectively detect and diagnose various tumors and kidney injury in mouse models using multispectral optoacoustic imaging.
NATURE COMMUNICATIONS
(2023)
