Elucidation of Dietary Polyphenolics as Potential Inhibitor of Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies
出版年份 2017 全文链接
标题
Elucidation of Dietary Polyphenolics as Potential Inhibitor of Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies
作者
关键词
-
出版物
Scientific Reports
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-08-21
DOI
10.1038/s41598-017-09941-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Binding studies and biological evaluation of β-carotene as a potential inhibitor of human calcium/calmodulin-dependent protein kinase IV
- (2017) Huma Naz et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Rhamnetin induces sensitization of hepatocellular carcinoma cells to a small molecular kinase inhibitor or chemotherapeutic agents
- (2016) Hui Jia et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Structure guided design of potential inhibitors of human calcium–calmodulin dependent protein kinase IV containing pyrimidine scaffold
- (2016) Huma Naz et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Design, synthesis, and biological evaluation of pyrimidine derivatives as potential inhibitors of human calcium/calmodulin-dependent protein kinase IV
- (2016) Ehtesham Jameel et al. Chemical Biology & Drug Design
- miR‐515‐5p controls cancer cell migration through MARK4 regulation
- (2016) Olivier E Pardo et al. EMBO REPORTS
- Ubiquitin-associated domain of MARK4 provides stability at physiological pH
- (2016) Farha Naz et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Distinctive Metabolism of Flavonoid between Cultivated and Semiwild Soybean Unveiled through Metabolomics Approach
- (2016) Dae-Yong Yun et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays
- (2016) Farha Naz et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Flavanone Intake Is Inversely Associated with Risk of Incident Ischemic Stroke in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study
- (2016) Margarethe E Goetz et al. JOURNAL OF NUTRITION
- Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer’s disease treatment
- (2016) Wenchao Sun et al. Scientific Reports
- Mark4 promotes oxidative stress and inflammation via binding to PPARγ and activating NF-κB pathway in mice adipocytes
- (2016) Zhenjiang Liu et al. Scientific Reports
- Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis
- (2016) Shikha Srivastava et al. Scientific Reports
- Edible Flowers: A Rich Source of Phytochemicals with Antioxidant and Hypoglycemic Properties
- (2015) Monica Rosa Loizzo et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Accumulation of Rutin and Betulinic Acid and Expression of Phenylpropanoid and Triterpenoid Biosynthetic Genes in Mulberry (Morus alba L.)
- (2015) Shicheng Zhao et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Curcumin specifically binds to the human calcium–calmodulin-dependent protein kinase IV: fluorescence and molecular dynamics simulation studies
- (2015) Nasimul Hoda et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- PKR-inhibitor binds efficiently with human microtubule affinity-regulating kinase 4
- (2015) Farha Naz et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Atypical PKC phosphorylates microtubule affinity-regulating kinase 4 in vitro
- (2015) Farha Naz et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Designing New Kinase Inhibitor Derivatives as Therapeutics Against Common Complex Diseases: Structural Basis of Microtubule Affinity-Regulating Kinase 4 (MARK4) Inhibition
- (2015) Farha Naz et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Dietary flavonoid intake at midlife and healthy aging in women
- (2014) Cécilia Samieri et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Cloning, Expression, Purification and Refolding of Microtubule Affinity-Regulating Kinase 4 Expressed in Escherichia coli
- (2014) Farha Naz et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) plays a role in cell cycle progression and cytoskeletal dynamics
- (2014) Davide Rovina et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Bioactive Compounds from Culinary Herbs Inhibit a Molecular Target for Type 2 Diabetes Management, Dipeptidyl Peptidase IV
- (2014) Allyson M. Bower et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progression
- (2014) Pranitha Jenardhanan et al. Molecular BioSystems
- Microtubule Affinity-Regulating Kinase 4: Structure, Function, and Regulation
- (2013) Farha Naz et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Rutin (Quercetin Rutinoside) Induced Protein-Energy Malnutrition in Chronic Kidney Disease, but Quercetin Acted Beneficially
- (2013) Chiu-Lan Hsieh et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy
- (2013) Ying Liu et al. Scientific Reports
- Dietary flavonoid intakes and risk of type 2 diabetes in US men and women
- (2012) Nicole M Wedick et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Microtubule-associated Protein/Microtubule Affinity-regulating Kinase 4 (MARK4) Is a Negative Regulator of the Mammalian Target of Rapamycin Complex 1 (mTORC1)
- (2012) Li Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modified Annexin V/Propidium Iodide Apoptosis Assay For Accurate Assessment of Cell Death
- (2011) Aja M. Rieger et al. Jove-Journal of Visualized Experiments
- Evaluation of antioxidant activity of vanillin by using multiple antioxidant assays
- (2010) Akihiro Tai et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Soy isoflavones consumption and risk of breast cancer incidence or recurrence: a meta-analysis of prospective studies
- (2010) Jia-Yi Dong et al. BREAST CANCER RESEARCH AND TREATMENT
- Genistein Induces Pancreatic β-Cell Proliferation through Activation of Multiple Signaling Pathways and Prevents Insulin-Deficient Diabetes in Mice
- (2010) Zhuo Fu et al. ENDOCRINOLOGY
- Structure and function of polarity-inducing kinase family MARK/Par-1 within the branch of AMPK/Snf1-related kinases
- (2010) A. Marx et al. FASEB JOURNAL
- Computer-aided drug design platform using PyMOL
- (2010) Markus A. Lill et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain
- (2010) Jeremy P. E. Spencer PROCEEDINGS OF THE NUTRITION SOCIETY
- AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
- (2009) Garrett M. Morris et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- The role of tau in neurodegeneration
- (2009) Tania F Gendron et al. Molecular Neurodegeneration
- Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells
- (2008) Naghma Khan et al. CARCINOGENESIS
- Medicinal Plants and Cancer Chemoprevention
- (2008) Avni Desai et al. CURRENT DRUG METABOLISM
- In vitro antioxidant properties of rutin
- (2007) Jianxiong Yang et al. LWT-FOOD SCIENCE AND TECHNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started