Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway
出版年份 2017 全文链接
标题
Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway
作者
关键词
-
出版物
Scientific Reports
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-01-24
DOI
10.1038/srep41254
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Application of metabolomics to investigate the antitumor mechanism of flavopiridol in MCF-7 breast cancer cells
- (2016) Xiaojian Shao et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Potential Anti-Cancer Activities and Mechanisms of Costunolide and Dehydrocostuslactone
- (2015) Xuejing Lin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction from Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway
- (2015) Jhi Biau Foo et al. JOURNAL OF ETHNOPHARMACOLOGY
- Study on the pharmacokinetics and metabolism of costunolide and dehydrocostus lactone in rats by HPLC-UV and UPLC-Q-TOF/MS
- (2014) Zhangxiao Peng et al. BIOMEDICAL CHROMATOGRAPHY
- Metabolic transformation of breast cancer in a MCF-7 xenograft mouse model and inhibitory effect of volatile oil from Saussurea lappa Decne treatment
- (2014) Zhang-xiao Peng et al. Metabolomics
- A platform for fast screening potential anti-breast cancer compounds in traditional Chinese medicines
- (2013) Zhang-xiao Peng et al. BIOMEDICAL CHROMATOGRAPHY
- Sesquiterpene Lactones Downregulate G2/M Cell Cycle Regulator Proteins and Affect the Invasive Potential of Human Soft Tissue Sarcoma Cells
- (2013) Birgit Lohberger et al. PLoS One
- Occurrence and Detection of Phosphopeptide Isomers in Large-Scale Phosphoproteomics Experiments
- (2012) Mathieu Courcelles et al. JOURNAL OF PROTEOME RESEARCH
- FoxO transcription factors; Regulation by AKT and 14-3-3 proteins
- (2011) Guri Tzivion et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Costunolide induces apoptosis in platinum-resistant human ovarian cancer cells by generating reactive oxygen species
- (2011) Yeong-In Yang et al. GYNECOLOGIC ONCOLOGY
- Costunolide causes mitotic arrest and enhances radiosensitivity in human hepatocellular carcinoma cells
- (2011) Chia-Yuan Liu et al. Radiation Oncology
- Comparative protein profile of human hepatoma HepG2 cells treated with graphene and single-walled carbon nanotubes: An iTRAQ-coupled 2D LC–MS/MS proteome analysis
- (2011) Jifeng Yuan et al. TOXICOLOGY LETTERS
- Costunolide-Induced Apoptosis in Human Leukemia Cells: Involvement of c-Jun N-Terminal Kinase Activation
- (2009) Jung-Hye Choi et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Hepatoprotective effects of daidzein against 7,12-dimetylbenz[α]anthracene-induced oxidative stress in mice
- (2009) Choi INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Isolation of Betulinic Acid, its Methyl Ester and Guaiane Sesquiterpenoids with Protein Tyrosine Phosphatase 1B Inhibitory Activity from the Roots of Saussurea lappa C.B.Clarke
- (2009) Ji Choi et al. MOLECULES
- Analytical strategies for phosphoproteomics
- (2009) Tine E. Thingholm et al. PROTEOMICS
- Costunolide-Induced Apoptosis Is Caused by Receptor-Mediated Pathway and Inhibition of Telomerase Activity in NALM-6 Cells
- (2008) Syu-ichi Kanno et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Apoptosis of DU145 human prostate cancer cells induced by dehydrocostus lactone isolated from the root of Saussurea lappa
- (2008) Eun Ji Kim et al. FOOD AND CHEMICAL TOXICOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started