Co-encapsulation and co-transplantation of mesenchymal stem cells reduces pericapsular fibrosis and improves encapsulated islet survival and function when allografted

Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

(2015) Omid Veiseh et al.   NATURE MATERIALS

Improvement of Subcutaneous Bioartificial Pancreas Vascularization and Function by Coencapsulation of Pig Islets and Mesenchymal Stem Cells in Primates

(2014) Sophie Vériter et al.   CELL TRANSPLANTATION

Co-transplantation of islets with mesenchymal stem cells in microcapsules demonstrates graft outcome can be improved in an isolated-graft model of islet transplantation in mice

(2013) Alan Kerby et al.   CYTOTHERAPY

Sustained function of alginate-encapsulated human islet cell implants in the peritoneal cavity of mice leading to a pilot study in a type 1 diabetic patient

(2013) D. Jacobs-Tulleneers-Thevissen et al.   DIABETOLOGIA

Considerations in binding diblock copolymers on hydrophilic alginate beads for providing an immunoprotective membrane

(2013) Milica Spasojevic et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Characterisation of the Xenogeneic Immune Response to Microencapsulated Fetal Pig Islet-Like Cell Clusters Transplanted into Immunocompetent C57BL/6 Mice

(2013) Vijayaganapathy Vaithilingam et al.   PLoS One

Improving alginate-poly-L-ornithine-alginate capsule biocompatibility through genipin crosslinking

(2012) Anna L. Hillberg et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Enhancement of Surface Graft Density of MPEG on Alginate/Chitosan Hydrogel Microcapsules for Protein Repellency

(2012) Jiani Zheng et al.   LANGMUIR

Immunomodulatory Properties of Mesenchymal Stem Cells: Cytokines and Factors

(2011) Ehsan Soleymaninejadian et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Immunomodulatory properties and therapeutic application of mesenchymal stem cells

(2011) M. Shi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts: Four cases

(2011) G. Basta et al.   DIABETES CARE

Effect of prolonged gelling time on the intrinsic properties of barium alginate microcapsules and its biocompatibility

(2011) Vijayaganapathy Vaithilingam et al.   JOURNAL OF MICROENCAPSULATION

Bone marrow-derived mesenchymal stromal cells support rat pancreatic islet survival and insulin secretory function in vitro

(2010) Eun-Jung Jung et al.   CYTOTHERAPY

Mesenchymal Stem Cells Prevent Acute Rejection and Prolong Graft Function in Pancreatic Islet Transplantation

(2010) Biancamaria Longoni et al.   Diabetes Technology & Therapeutics

Bone Marrow Cell Cotransplantation With Islets Improves Their Vascularization and Function

(2010) Naoaki Sakata et al.   TRANSPLANTATION

Mesenchymal Stem Cell and Islet Co-Transplantation Promotes Graft Revascularization and Function

(2010) Taihei Ito et al.   TRANSPLANTATION

Protection of rat pancreatic islet function and viability by coculture with rat bone marrow-derived mesenchymal stem cells

(2010) E Karaoz et al.   Cell Death & Disease

Mesenchymal stromal cells promote or suppress the proliferation of T lymphocytes from cord blood and peripheral blood: the importance of low cell ratio and role of interleukin-6

(2009) Mehdi Najar et al.   CYTOTHERAPY

Deletion of PKC  Selectively Enhances the Amplifying Pathways of Glucose-Stimulated Insulin Secretion via Increased Lipolysis in Mouse  -Cells

(2009) J. Cantley et al.   DIABETES

Mesenchymal Stem Cells Prevent the Rejection of Fully Allogenic Islet Grafts by the Immunosuppressive Activity of Matrix Metalloproteinase-2 and -9

(2009) Y. Ding et al.   DIABETES

Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans

(2009) B. E. Tuch et al.   DIABETES CARE

Marginal mass islet transplantation with autologous mesenchymal stem cells promotes long-term islet allograft survival and sustained normoglycemia

(2009) Mario G. Solari et al.   JOURNAL OF AUTOIMMUNITY

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R

(2009) Christiane A. Opitz et al.   STEM CELLS

Influence of Human Allogenic Bone Marrow and Cord Blood–Derived Mesenchymal Stem Cell Secreting Trophic Factors on ATP (adenosine-5′-triphosphate)/ADP (adenosine-5′-diphosphate) Ratio and Insulin Secretory Function of Isolated Human Islets From Cadaveric Donor

(2009) K.S. Park et al.   TRANSPLANTATION PROCEEDINGS

Bone Marrow–Derived Mesenchymal Stem Cells Improve Islet Graft Function in Diabetic Rats

(2009) M. Figliuzzi et al.   TRANSPLANTATION PROCEEDINGS

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

Viral IL-10 Gene Transfer Prolongs Rat Islet Allograft Survival

(2008) Yang-Hee Kim et al.   CELL TRANSPLANTATION

IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

(2008) David Polchert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pancreatic Beta-Cell Purification by Altering FAD and NAD(P)H Metabolism

(2008) M. J. Smelt et al.   Experimental Diabetes Research

Clinical Applications of Blood-Derived and Marrow-Derived Stem Cells for Nonmalignant Diseases

(2008) Richard K. Burt   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

Bone Marrow-Derived Mesenchymal Stem Cells Ameliorate Autoimmune Enteropathy Independently of Regulatory T Cells

(2008) Biju Parekkadan et al.   STEM CELLS