GLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activation

Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells

(2016) Søren Fisker Schmidt et al.   Cell Reports

The impact of cryopreservation on human peripheral blood leucocyte bioenergetics

(2015) Kevin N. Keane et al.   CLINICAL SCIENCE

Synaptotagmin-7 phosphorylation mediates GLP-1–dependent potentiation of insulin secretion from β-cells

(2015) Bingbing Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Exenatide, Sitagliptin, or Glimepiride on β-Cell Secretory Capacity in Early Type 2 Diabetes

(2014) Lalitha Gudipaty et al.   DIABETES CARE

Liraglutide and the Preservation of Pancreatic β-Cell Function in Early Type 2 Diabetes: The LIBRA Trial

(2014) Ravi Retnakaran et al.   DIABETES CARE

Exendin-4 stimulates islet cell replication via the IGF1 receptor activation of mTORC1/S6K1

(2014) J. Xie et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Incretin-Modulated Beta Cell Energetics in Intact Islets of Langerhans

(2014) David J. Hodson et al.   MOLECULAR ENDOCRINOLOGY

Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1 

(2014) B. Faubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

(2014) Ghupurjan Gheni et al.   Cell Reports

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

Nutrient Sensing, Metabolism, and Cell Growth Control

(2013) Hai-Xin Yuan et al.   MOLECULAR CELL

SAD-A kinase controls islet β-cell size and function as a mediator of mTORC1 signaling

(2013) Jia Nie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GLP-1 receptor activated insulin secretion from pancreatic β-cells: mechanism and glucose dependence

(2012) A. R. Meloni et al.   DIABETES OBESITY & METABOLISM

The human glucagon-like peptide-1 analogue liraglutide regulates pancreatic beta-cell proliferation and apoptosis via an AMPK/mTOR/P70S6K signaling pathway

(2012) Xin-Yu Miao et al.   PEPTIDES

Effects of Exenatide on Measures of  -Cell Function After 3 Years in Metformin-Treated Patients With Type 2 Diabetes

(2011) M. C. Bunck et al.   DIABETES CARE

Glucagon-Like Peptide-1 Enhances Glucokinase Activity in Pancreatic β-Cells through the Association of Epac2 with Rim2 and Rab3A

(2011) Jae-Hyung Park et al.   ENDOCRINOLOGY

Glucagon-like Peptide 1 Stimulates Post-translational Activation of Glucokinase in Pancreatic β Cells

(2011) Shi-Ying Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR links incretin signaling to HIF induction in pancreatic beta cells

(2011) S. Van de Velde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIF-1: upstream and downstream of cancer metabolism

(2009) Gregg L Semenza   CURRENT OPINION IN GENETICS & DEVELOPMENT

Glucagon-Like Peptide-1 Induced Signaling and Insulin Secretion Do Not Drive Fuel and Energy Metabolism in Primary Rodent Pancreatic β-Cells

(2009) Marie-Line Peyot et al.   PLoS One

Advances in measuring cellular bioenergetics using extracellular flux

(2008) David A. Ferrick et al.   DRUG DISCOVERY TODAY

Role of the cAMP sensor Epac as a determinant of KATPchannel ATP sensitivity in human pancreatic β-cells and rat INS-1 cells

(2008) Guoxin Kang et al.   JOURNAL OF PHYSIOLOGY-LONDON