Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

(2016) Natalie E. de Picciotto et al.   AGING CELL

AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD+elevation

(2016) Xiaojuan Han et al.   AGING CELL

Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death

(2016) Xiaonan Wang et al.   BRAIN RESEARCH

Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis

(2016) Shu-Na Wang et al.   CNS Neuroscience & Therapeutics

Neuroprotective Efficacy of an Aminopropyl Carbazole Derivative P7C3-A20 in Ischemic Stroke

(2016) Shu-Na Wang et al.   CNS Neuroscience & Therapeutics

Stereotactic Administration of Edaravone Ameliorates Collagenase-Induced Intracerebral Hemorrhage in Rat

(2016) Yan Zhang et al.   CNS Neuroscience & Therapeutics

Enhancing NAD+Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1)

(2016) Benjamin A. Harlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beyond knockout: A novel homodimerization-targeting MyD88 inhibitor prevents and cures type 1 diabetes in NOD mice

(2016) Xue Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Exercise-stimulated FGF23 promotes exercise performance via controlling the excess reactive oxygen species production and enhancing mitochondrial function in skeletal muscle

(2016) Dong-Jie Li et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The potential regulatory roles of NAD+ and its metabolism in autophagy

(2016) Dong-Xia Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Depletion of NAD pool contributes to impairment of endothelial progenitor cell mobilization in diabetes

(2016) Pei Wang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Atorvastatin prevents advanced glycation end products (AGEs)-induced cardiac fibrosis via activating peroxisome proliferator-activated receptor gamma (PPAR-γ)

(2016) Miao Chen et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Nicotinamide mononucleotide inhibits post-ischemic NAD+ degradation and dramatically ameliorates brain damage following global cerebral ischemia

(2016) Ji H. Park et al.   NEUROBIOLOGY OF DISEASE

Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer’s disease-relevant murine model

(2015) Aaron N Long et al.   BMC Neurology

Chemokines as effector and target molecules in vascular biology

(2015) Silvano Sozzani et al.   CARDIOVASCULAR RESEARCH

Fanning the flames: inflammation in cardiovascular diseases

(2015) Peter Libby   CARDIOVASCULAR RESEARCH

Monocyte trafficking across the vessel wall

(2015) Teresa Gerhardt et al.   CARDIOVASCULAR RESEARCH

PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis

(2015) Hayley Mylroie et al.   CARDIOVASCULAR RESEARCH

SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice

(2015) Myeong Jin Yoon et al.   Cell Metabolism

Niacin inhibits fat accumulation, oxidative stress, and inflammatory cytokine IL-8 in cultured hepatocytes: Impact on non-alcoholic fatty liver disease

(2015) Shobha H. Ganji et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Regenerative Neurogenesis After Ischemic Stroke Promoted by Nicotinamide Phosphoribosyltransferase–Nicotinamide Adenine Dinucleotide Cascade

(2015) Yan Zhao et al.   STROKE

NAMPT as a Therapeutic Target against Stroke

(2015) Pei Wang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia

(2014) Pei Wang et al.   Autophagy

Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia

(2014) Valentina Audrito et al.   BLOOD

Intracellular NAMPT–NAD+–SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors

(2014) Pei Wang et al.   CARDIOVASCULAR RESEARCH

Extracellular Visfatin has Nicotinamide Phosphoribosyltransferase Enzymatic Activity and is Neuroprotective Against Ischemic Injury

(2014) Yan Zhao et al.   CNS Neuroscience & Therapeutics

Mouse Intracerebral Hemorrhage Models Produce Different Degrees of Initial and Delayed Damage, Axonal Sprouting, and Recovery

(2014) Harriet E Barratt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroinflammation after intracerebral hemorrhage

(2014) Eva Mracsko et al.   Frontiers in Cellular Neuroscience

NAD+ protects against EAE by regulating CD4+ T-cell differentiation

(2014) Stefan G. Tullius et al.   Nature Communications

New Insights on NOX Enzymes in the Central Nervous System

(2013) Zeynab Nayernia et al.   ANTIOXIDANTS & REDOX SIGNALING

Cellular NAD depletion and decline of SIRT1 activity play critical roles in PARP-1-mediated acute epileptic neuronal death in vitro

(2013) Shengjun Wang et al.   BRAIN RESEARCH

Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation

(2013) Yu Zhou et al.   PROGRESS IN NEUROBIOLOGY

Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia

(2012) Pei Wang et al.   Autophagy

Loss of AMP-Activated Protein Kinase-α2 Impairs the Insulin-Sensitizing Effect of Calorie Restriction in Skeletal Muscle

(2012) Pei Wang et al.   DIABETES

Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

(2012) Richard F Keep et al.   LANCET NEUROLOGY

A fluorometric assay for high-throughput screening targeting nicotinamide phosphoribosyltransferase

(2011) Ruo-Yu Zhang et al.   ANALYTICAL BIOCHEMISTRY

Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

(2011) Pei Wang et al.   ANNALS OF NEUROLOGY

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

(2011) Jun Yoshino et al.   Cell Metabolism

Nicotinamide mononucleotide protects against pro-inflammatory cytokine-mediated impairment of mouse islet function

(2011) P. W. Caton et al.   DIABETOLOGIA

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

A Retinoic Acid Receptor Agonist Am80 Rescues Neurons, Attenuates Inflammatory Reactions, and Improves Behavioral Recovery after Intracerebral Hemorrhage in Mice

(2010) Hideaki Matsushita et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

NAD+ Depletion Is Necessary and Sufficient forPoly(ADP-Ribose) Polymerase-1-Mediated Neuronal Death

(2010) C. C. Alano et al.   JOURNAL OF NEUROSCIENCE

Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo

(2009) Laura Formentini et al.   BIOCHEMICAL PHARMACOLOGY

Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

(2009) Frédéric Van Gool et al.   NATURE MEDICINE

Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide

(2008) Pei Wang et al.   CARDIOVASCULAR RESEARCH

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1

(2008) Claude A. Piantadosi et al.   CIRCULATION RESEARCH