Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 Human Colon Cancer Cells

Feedback control of AHR signalling regulates intestinal immunity

(2017) Chris Schiering et al.   NATURE

Smad7 Knockdown Restores Aryl Hydrocarbon Receptor-mediated Protective Signals in the Gut

(2016) Ivan Monteleone et al.   Journal of Crohns & Colitis

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

(2016) Bruno Lamas et al.   NATURE MEDICINE

Editor’s Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure–Activity Relationships and Receptor Modeling

(2016) Yating Cheng et al.   TOXICOLOGICAL SCIENCES

Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation

(2015) Nicola Gagliani et al.   NATURE

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

(2015) Troy D. Hubbard et al.   Scientific Reports

Diet, Metabolites, and “Western-Lifestyle” Inflammatory Diseases

(2014) Alison N. Thorburn et al.   IMMUNITY

Identification of a probiotic bacteria-derived activator of the aryl hydrocarbon receptor that inhibits colitis

(2014) Suguru Fukumoto et al.   IMMUNOLOGY AND CELL BIOLOGY

Dietary modulation of the microbiome affects autoinflammatory disease

(2014) John R. Lukens et al.   NATURE

The emerging roles of AhR in physiology and immunity

(2013) Nan Hao et al.   BIOCHEMICAL PHARMACOLOGY

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Use of natural AhR ligands as potential therapeutic modalities against inflammatory disorders

(2013) Philip B Busbee et al.   NUTRITION REVIEWS

Biology and function of the aryl hydrocarbon receptor: report of an international and interdisciplinary conference

(2012) Charlotte Esser   ARCHIVES OF TOXICOLOGY

Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent Mechanisms

(2012) Janet E. Digby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate

(2012) Kim Y. C. Fung et al.   BRITISH JOURNAL OF NUTRITION

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

(2011) Ying Li et al.   CELL

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

(2011) Ju Qiu et al.   IMMUNITY

Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles

(2011) E. A. Kiss et al.   SCIENCE

Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

(2011) Michael S. Denison et al.   TOXICOLOGICAL SCIENCES

Dioxin and immune regulation

(2010) Nikki B. Marshall et al.   Annals of the New York Academy of Sciences

GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

(2009) M. Thangaraju et al.   CANCER RESEARCH

The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

(2009) Emily A. Stevens et al.   IMMUNOLOGY

HDAC6 Modulates Hsp90 Chaperone Activity and Regulates Activation of Aryl Hydrocarbon Receptor Signaling

(2009) Vikram D. Kekatpure et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

(2008) Markus Waldecker et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY