Biological evaluation of dinuclear copper complex/dichloroacetic acid cocrystal against human breast cancer: design, synthesis, characterization, DFT studies and cytotoxicity assays

Heteroleptic Copper(I) Complexes of “Scorpionate” Bis-pyrazolyl Carboxylate Ligand with Auxiliary Phosphine as Potential Anticancer Agents: An Insight into Cytotoxic Mode

(2017) Rais Ahmad Khan et al.   Scientific Reports

Drug–drug co-crystallization presents a new opportunity for the development of stable vitamins

(2016) Jian-Rong Wang et al.   CHEMICAL COMMUNICATIONS

Multiple Weak C–H Intramolecular Hydrogen Bonding as an Aid to Minimizing Bond Rotation Flexibility

(2016) John Andrew Harrison et al.   CRYSTAL GROWTH & DESIGN

Drug–Drug Multicomponent Crystals as an Effective Technique to Overcome Weaknesses in Parent Drugs

(2016) Okky Dwichandra Putra et al.   CRYSTAL GROWTH & DESIGN

A comparative analyses of bioactive Cu(II) complexes using Hirshfeld surface and density functional theory (DFT) methods: DNA binding studies, cleavage and antibiofilm activities

(2016) Mohammad Usman et al.   INORGANICA CHIMICA ACTA

Transition-metal norharmane compounds as possible cytotoxic agents: New insights based on a coordination chemistry perspective

(2016) Rais Ahmad Khan et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Vanillinyl thioether Schiff base as a turn-on fluorescence sensor to Zn 2+ ion with living cell imaging

(2016) Chiranjit Patra et al.   SENSORS AND ACTUATORS B-CHEMICAL

Lenalidomide–Gallic Acid Cocrystals with Constant High Solubility

(2015) Jia-Xi Song et al.   CRYSTAL GROWTH & DESIGN

Mechanistic insights into a novel chromone-appended Cu(ii) anticancer drug entity: in vitro binding profile with DNA/RNA substrates and cytotoxic activity against MCF-7 and HepG2 cancer cells

(2015) Imtiyaz Yousuf et al.   DALTON TRANSACTIONS

A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors

(2015) Quincy Siu-Chung Chu et al.   INVESTIGATIONAL NEW DRUGS

Design, synthesis and characterization of novel binary V(V)-Schiff base materials linked with insulin-mimetic vanadium-induced differentiation of 3T3-L1 fibroblasts to adipocytes. Structure–function correlations at the molecular level

(2015) E. Halevas et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Enhancing the copper(II) complexes cytotoxicity to cancer cells through bound to human serum albumin

(2015) Yi Gou et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Tuning Mechanical Properties of Pharmaceutical Crystals with Multicomponent Crystals: Voriconazole as a Case Study

(2015) Palash Sanphui et al.   MOLECULAR PHARMACEUTICS

Synthesis and spectroscopic characterization of diorganotin(iv) complexes of N′-(4-hydroxypent-3-en-2-ylidene)isonicotinohydrazide: chemotherapeutic potential validation by in vitro interaction studies with DNA/HSA, DFT, molecular docking and cytotoxic activity

(2015) Shipra Yadav et al.   RSC Advances

An efficient vanillinyl Schiff base as a turn on fluorescent probe for zinc(ii) and cell imaging

(2015) Anup Kumar Bhanja et al.   RSC Advances

Dichloroacetate induces autophagy in colorectal cancer cells and tumours

(2014) G Lin et al.   BRITISH JOURNAL OF CANCER

Mixed ligand μ-phenoxo-bridged dinuclear copper(ii) complexes with diimine co-ligands: efficient chemical nuclease and protease activities and cytotoxicity

(2014) Rangasamy Loganathan et al.   DALTON TRANSACTIONS

Binuclear copper complexes: Synthesis, X-ray structure and interaction study with nucleotide/protein by in vitro biochemical and electrochemical analysis

(2014) M. Alagesan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Copper(I) halide complexes of 5-carbethoxy-2-thiouracil: Synthesis, structure and in vitro cytotoxicity

(2014) I. Papazoglou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ligand effect and cooperative role of metal ions on the DNA cleavage efficiency of mono and binuclear Cu(II) macrocyclic ligands complexes

(2014) Nataraj Chitrapriya et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Light-stable bis(norharmane)silver(I) compounds: Synthesis, characterization and antiproliferative effects in cancer cells

(2014) Rais Ahmad Khan et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Structural Diversity of Copper(II) Complexes with N-(2-Pyridyl)Imidazolidin-2-Ones(Thiones) and Their in Vitro Antitumor Activity

(2014) Łukasz Balewski et al.   MOLECULES

Clinical update on cancer: molecular oncology of head and neck cancer

(2014) Y Suh et al.   Cell Death & Disease

Advances in Copper Complexes as Anticancer Agents

(2013) Carlo Santini et al.   CHEMICAL REVIEWS

Ligand dependent self-assembly of hydroxido-bridged dicopper units templated by sodium ion

(2013) Avijit Sarkar et al.   DALTON TRANSACTIONS

New ruthenium(ii) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and cleavage and cytotoxicity

(2013) Mani Ganeshpandian et al.   DALTON TRANSACTIONS

Enhancing Effects of Electron-Withdrawing Groups and Metallic Ions on Halogen Bonding in the YC6F4X···C2H8N2 (X = Cl, Br, I; Y = F, CN, NO2, LiNC+, NaNC+) Complex

(2013) Na Han et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Unraveling non-covalent interactions within flexible biomolecules: from electron density topology to gas phase spectroscopy

(2013) R. Chaudret et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

The role of co-crystals in pharmaceutical design

(2013) Jonathan W. Steed   TRENDS IN PHARMACOLOGICAL SCIENCES

Evaluation of DNA-binding, radical scavenging and cytotoxic activity of five coordinated Cd(ii) complexes containing 2-acetylpyridine-N4-substituted thiosemicarbazone

(2013) Rajendran Manikandan et al.   RSC Advances

Crystal Engineering of Isostructural Quaternary Multicomponent Crystal Forms of Olanzapine

(2012) Heather D. Clarke et al.   CRYSTAL GROWTH & DESIGN

Polymorphs, Salts, and Cocrystals: What’s in a Name?

(2012) Srinivasulu Aitipamula et al.   CRYSTAL GROWTH & DESIGN

Drug-drug co-crystals: Temperature-dependent proton mobility in the molecular complex of isoniazid with 4-aminosalicylic acid

(2011) Pawel Grobelny et al.   CRYSTENGCOMM

Biological evaluation of a novel water soluble sulphur bridged binuclear copper(II) thiosemicarbazone complex

(2011) Duraisamy Senthil Raja et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

NCIPLOT: A Program for Plotting Noncovalent Interaction Regions

(2011) Julia Contreras-García et al.   Journal of Chemical Theory and Computation

Single-Molecule Magnet Behavior for an Antiferromagnetically Superexchange-Coupled Dinuclear Dysprosium(III) Complex

(2011) Jérôme Long et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mixed ligand cobalt(ii) picolinate complexes: synthesis, characterization, DNA binding and photocleavage

(2010) Vitthal A. Kawade et al.   DALTON TRANSACTIONS

Chiral preference of l-tryptophan derived metal-based antitumor agent of late 3d-metal ions (Co(II), Cu(II) and Zn(II)) in comparison to d- and dl-tryptophan analogues: Their in vitro reactivity towards CT DNA, 5′-GMP and 5′-TMP

(2010) Farukh Arjmand et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC

(2010) Luke H. Stockwin et al.   INTERNATIONAL JOURNAL OF CANCER

A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu

(2010) Stefan Grimme et al.   JOURNAL OF CHEMICAL PHYSICS

Gabedit-A graphical user interface for computational chemistry softwares

(2010) Abdul-Rahman Allouche   JOURNAL OF COMPUTATIONAL CHEMISTRY

Copper(II) complex of in situ formed 5-(2-pyridyl)-1,3,4-triazole through C–S bond cleavage in 1,2-bis(2-pyridylmethylthio)-bis-ethylsulphide: Synthesis, structural characterization and DNA binding study

(2010) Sandipan Sarkar et al.   JOURNAL OF MOLECULAR STRUCTURE

Coformer Selection in Pharmaceutical Cocrystal Development: a Case Study of a Meloxicam Aspirin Cocrystal That Exhibits Enhanced Solubility and Pharmacokinetics

(2010) Miranda L. Cheney et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Crystal Engineering of Pharmaceutical Co-crystals: Application of Methyl Paraben as Molecular Hook

(2010) Mujeeb Khan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Revealing Noncovalent Interactions

(2010) Erin R. Johnson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cocrystallized Dinuclear−Mononuclear CuII3NaIand Double-Decker−Triple-Decker CuII5KI3Complexes Derived fromN,N′-Ethylenebis(3-ethoxysalicylaldimine)

(2009) Susanta Hazra et al.   CRYSTAL GROWTH & DESIGN

Pharmaceutical Cocrystals and Their Physicochemical Properties

(2009) Nate Schultheiss et al.   CRYSTAL GROWTH & DESIGN

Trimorphs of a pharmaceutical cocrystal involving two active pharmaceutical ingredients: potential relevance to combination drugs

(2009) Srinivasulu Aitipamula et al.   CRYSTENGCOMM

Syntheses and crystal structures of CuIIBiIII, CuIIBaIICuII, [CuIIPbII]2 and cocrystallized (UVIO2)2.4CuIIcomplexes: structural diversity of the coordination compounds derived from N,N′-ethylenebis(3-ethoxysalicylaldiimine)

(2009) Susanta Hazra et al.   CRYSTENGCOMM

Syntheses, Crystal Structures and Mass Spectrometry of Mononuclear NiIIInclusion Product and Self-Assembled [2 × 1+1 × 2] NiII3MII(M = Cu, Ni, Co, Fe or Mn) Cocrystals Derived fromN,N′-Ethylenebis(3-ethoxysalicylaldimine)

(2009) Sohini Sarkar et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Vanillin Suppresses Metastatic Potential of Human Cancer Cells through PI3K Inhibition and Decreases Angiogenesis in Vivo

(2009) Kriengsak Lirdprapamongkol et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hirshfeld surface analysis

(2008) Mark A. Spackman et al.   CRYSTENGCOMM

New trends for metal complexes with anticancer activity

(2008) Pieter CA Bruijnincx et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Synthesis, structural characterization, antiradical and antidiabetic activities of copper(II) and zinc(II) Schiff base complexes derived from salicylaldehyde and β-alanine

(2007) Ján Vančo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY