Versatile magnetic resonance singlet tags compatible with biological conditions

Limits in Proton Nuclear Singlet-State Lifetimes Measured with para -Hydrogen-Induced Polarization

(2016) Yuning Zhang et al.   CHEMPHYSCHEM

Dissolution DNP for in vivo preclinical studies

(2016) Arnaud Comment   JOURNAL OF MAGNETIC RESONANCE

Ligand–Protein Affinity Studies Using Long-Lived States of Fluorine-19 Nuclei

(2016) Roberto Buratto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nuclear Spin Singlet Order Selection by Adiabatically Ramped RF Fields

(2016) Alexey S. Kiryutin et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Long-lived nuclear spin states in monodeuterated methyl groups

(2016) Stuart J. Elliott et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Direct and cost-efficient hyperpolarization of long-lived nuclear spin states on universal 15N2-diazirine molecular tags

(2016) T. Theis et al.   Science Advances

A Nuclear Singlet Lifetime of More than One Hour in Room-Temperature Solution

(2015) Gabriele Stevanato et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hyperpolarization of amino acid derivatives in water for biological applications

(2015) S. Glöggler et al.   Chemical Science

ParaHydrogen Induced Polarization of 13C carboxylate resonance in acetate and pyruvate

(2015) Francesca Reineri et al.   Nature Communications

Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

(2015) John Kurhanewicz et al.   NEOPLASIA

Exploring Weak Ligand-Protein Interactions by Long-Lived NMR States: Improved Contrast in Fragment-Based Drug Screening

(2014) Roberto Buratto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Long-Lived1H Nuclear Spin Singlet in Dimethyl Maleate Revealed by Addition of Thiols

(2014) Yuning Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR

(2014) Roberto Buratto et al.   ChemMedChem

Composite and shaped pulses for efficient and robust pumping of disconnected eigenstates in magnetic resonance

(2014) T. Theis et al.   JOURNAL OF CHEMICAL PHYSICS

The Thiol-Michael Addition Click Reaction: A Powerful and Widely Used Tool in Materials Chemistry

(2013) Devatha P. Nair et al.   CHEMISTRY OF MATERIALS

Storage of Hydrogen Spin Polarization in Long-Lived 13C2 Singlet Order and Implications for Hyperpolarized Magnetic Resonance Imaging

(2013) Yesu Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recycling and Imaging of Nuclear Singlet Hyperpolarization

(2013) Giuseppe Pileio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nuclear spin singlet states as a contrast mechanism for NMR spectroscopy

(2013) Stephen J. DeVience et al.   NMR IN BIOMEDICINE

Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate

(2013) S. J. Nelson et al.   Science Translational Medicine

Robust eco-friendly protocol for the preparation of γ-hydroxy-α,β-acetylenic esters by sequential one-pot elimination–addition of 2-bromoacrylates to aldehydes promoted by LTMP in 2-MeTHF

(2012) Vittorio Pace et al.   GREEN CHEMISTRY

Boosting the Sensitivity of Ligand–Protein Screening by NMR of Long-Lived States

(2012) Nicola Salvi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Accessing long-lived nuclear singlet states between chemically equivalent spins without breaking symmetry

(2012) Yesu Feng et al.   Nature Physics

Hyperbranched polymers for molecular imaging: designing polymers for parahydrogen induced polarisation (PHIP)

(2011) Kerstin Münnemann et al.   CHEMICAL COMMUNICATIONS

Paramagnetic relaxation of nuclear singlet states

(2011) Michael C. D. Tayler et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Singlet nuclear magnetic resonance of nearly-equivalent spins

(2011) Michael C. D. Tayler et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Extended para-hydrogenation monitored by NMR spectroscopy

(2010) Joel A. Tang et al.   CHEMICAL COMMUNICATIONS

Thiol-click chemistry: a multifaceted toolbox for small molecule and polymer synthesis

(2010) Charles E. Hoyle et al.   CHEMICAL SOCIETY REVIEWS

In SituDetection of PHIP at 48 mT: Demonstration Using a Centrally Controlled Polarizer

(2010) Kevin W. Waddell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Storage of nuclear magnetization as long-lived singlet order in low magnetic field

(2010) G. Pileio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radioactive Labeling of Defined HPMA-Based Polymeric Structures Using [18F]FETos for In Vivo Imaging by Positron Emission Tomography

(2009) Matthias M. Herth et al.   BIOMACROMOLECULES

Theory of long-lived nuclear spin states in solution nuclear magnetic resonance. II. Singlet spin locking

(2009) Giuseppe Pileio et al.   JOURNAL OF CHEMICAL PHYSICS

Diffusion Coefficients of Biomolecules Using Long-Lived Spin States

(2009) Puneet Ahuja et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Para-hydrogen induced polarization in homogeneous phase—an example of how ionic liquids affect homogenization and thus activation of catalysts

(2009) Torsten Gutmann et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Increasing Hyperpolarized Spin Lifetimes Through True Singlet Eigenstates

(2009) W. S. Warren et al.   SCIENCE

Hyperpolarized long-lived states in solution NMR: Three-spin case study in low field

(2008) Elena Vinogradov et al.   JOURNAL OF MAGNETIC RESONANCE

The Long-Lived Nuclear Singlet State of15N-Nitrous Oxide in Solution

(2008) Giuseppe Pileio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quality assurance of PASADENA hyperpolarization for 13C biomolecules

(2008) Jan-Bernd Hövener et al.   MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

Click chemistry reactions in medicinal chemistry: Applications of the 1,3-dipolar cycloaddition between azides and alkynes

(2007) Gian Cesare Tron et al.   MEDICINAL RESEARCH REVIEWS