Article
Medicine, General & Internal
Daniel J. Rubin, Preethi Gogineni, Andrew Deak, Cherie Vaz, Samantha Watts, Dominic Recco, Felicia Dillard, Jingwei Wu, Abhijana Karunakaran, Neil Kondamuri, Huaqing Zhao, Mary D. Naylor, Sherita H. Golden, Shaneisha Allen
Summary: The study explores the feasibility and efficacy of the Diabetes Transition of Hospital Care (DiaTOHC) Program on reducing readmission risk in high-risk adults with diabetes. The results suggest that the DiaTOHC program may decrease 30-day readmission/ED visit risk and healthcare costs.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Eric Bressman, Judith A. Long, Katherine Honig, Jarcy Zee, Nancy McGlaughlin, Carlondra Jointer, David A. Asch, Robert E. Burke, Anna U. Morgan
Summary: The findings of this cohort study suggest that an automated texting program to support primary care patients after hospital discharge was associated with significant reductions in the use of acute care resources. This patient-centered approach may serve as a model for improving postdischarge care.
Article
Medicine, General & Internal
Yue Wei, Vincent K. C. Yan, Wei Kang, Ian C. K. Wong, David J. Castle, Le Gao, Celine S. L. Chui, Kenneth K. C. Man, Joseph F. Hayes, Wing Chung Chang, Esther W. Chan
Summary: This study conducted a self-controlled case series study on patients with schizophrenia in Hong Kong and found that long-acting injectable antipsychotics were associated with lower risk of disease relapse and hospitalization compared to oral antipsychotics, without an increased risk of adverse events.
Article
Health Policy & Services
Lisa W. Goldstone, Bethany A. DiPaula, Amy Werremeyer, Sheila Botts, Brian Hepburn, Howard Y. Liu, Ken Duckworth, Alexander S. Young, Deanna L. Kelly
Summary: This article highlights the shortage of behavioral health providers in the United States and suggests expanding the number of board-certified psychiatric pharmacists (BCPPs) to address the need. It also points out five key areas in which BCPPs, along with other pharmacists, can provide evidence-based care as a collaborative solution to the mental health and substance use disorder crisis in the US.
PSYCHIATRIC SERVICES
(2021)
Article
Pharmacology & Pharmacy
Chong Li, Ke Lu, Qin Shi, Ya-qin Gong
Summary: This study developed and validated two novel, distinct-stage prediction nomograms that accurately estimate nonadherence risk among osteoporosis patients receiving the first infusion of zoledronic acid. External validation demonstrated good discrimination and calibration of these models.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE
(2022)
Article
Pediatrics
Mikaela Katz, Scott Gillespie, James P. Stevens, Lori Hall, Vasantha Kolachala, Ryan Ford, Keri Levin, Nitika A. Gupta
Summary: A retrospective study revealed that pediatric liver transplant recipients have higher mortality rates after transferring to adult care, with African Americans experiencing disproportionately higher mortality. This transition period is a vulnerable time for patients, and measures need to be taken to ensure the safe transfer of young adults with chronic health care needs.
JOURNAL OF PEDIATRICS
(2021)
Article
Urology & Nephrology
Ashton Chen
Summary: Young adult kidney transplant recipients have poorer outcomes, potentially due to complex factors, with consensus guidelines issued to guide the transition process but lacking investigation into potential barriers to implementation.
ADVANCES IN CHRONIC KIDNEY DISEASE
(2021)
Article
Gastroenterology & Hepatology
Jennifer Vittorio, Beverly Kosmach-Park, Lindsay Y. King, Ryan Fischer, Emily M. Fredericks, Vicky L. Ng, Amrita Narang, Sara Rasmussen, John Bucuvalas
Summary: Advancements in medical therapies and liver transplantation have allowed more pediatric patients to reach adulthood, but the transition from pediatric to adult hepatology and transplant services poses increased risks. Health care transition (HCT) is the process of shifting from child/family-centered care to adult/patient-centered care. This paper presents joint consensus guidelines to facilitate a structured, multidisciplinary approach to transition planning and calls for the implementation of an HCT program across pediatric and adult hepatology and transplant centers.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2023)
Article
Astronomy & Astrophysics
Mohammad Bagher Jahani Poshteh, Robert B. Mann
Summary: The thermodynamics of z = 4 Ho.rava-Lifshitz black holes in 3 + 1 dimensions is studied in extended phase space. By using the scaling argument, the Smarr relation and the first law for the black hole solutions of z = 4 Ho.rava-Lifshitz gravity are found. It is discovered that the reverse isoperimetric inequality can be violated for certain types of horizons, leading to positive specific heat at constant pressure and volume. Two critical points are identified for z = 4 Hovara-Lifshitz black holes with hyperbolic horizons, exhibiting both Van der Waals and reverse Van der Waals behaviors.
Article
Multidisciplinary Sciences
Maximilian Thees, Min-Han Lee, Rosa Luca Bouwmeester, Pedro H. Rezende-Goncalves, Emma David, Alexandre Zimmers, Franck Fortuna, Emmanouil Frantzeskakis, Nicolas M. Vargas, Yoav Kalcheim, Patrick Le Fevre, Koji Horiba, Hiroshi Kumigashira, Silke Biermann, Juan Trastoy, Marcelo J. Rozenberg, Ivan K. Schuller, Andres F. Santander-Syro
Summary: This study reveals the temperature-induced MIT in V2O3, characterized by the disappearance of its itinerant conduction band and the shift to larger binding energies of a quasi-localized state. These changes were observed through the energy- and momentum-resolved electronic structure using ARPES.
Article
Multidisciplinary Sciences
Andre Berchtold
Summary: In this study, a new class of predictive power measures for transition matrices is introduced to address the shortcomings of traditional association measures, allowing for better estimation of high-order Markov chain models.
Article
Materials Science, Multidisciplinary
C. G. L. Bottcher, F. Nichele, J. Shabani, C. J. Palmstrom, C. M. Marcus
Summary: In this study, we explore the vortex dynamics in a two-dimensional Josephson junction array. We observe that the minima of differential resistance undergo a transition and become local maxima at integer and half-integer flux quanta per plaquette. We also observe differences in the transition behavior between the superconducting and anomalous metal phases. Additionally, we find that the transitions show an overall even-odd pattern of skewing around integer f values, which we attribute to vortex commensuration in the square array.
Article
Environmental Sciences
Yufei Shi, Guochen Shen, Jinju Geng, Yingying Fu, Shengnan Li, Gang Wu, Liye Wang, Ke Xu, Hongqiang Ren
Summary: Pharmaceutically active compounds (PhACs) such as carbamazepine (CBZ), erythromycin (ERY), atenolol (ATL), and clofibric acid (CA) are frequently detected in aquatic environments, raising concerns due to their persistence and ecological risk. The UV/H2O2 advanced oxidation process is effective for removing pharmaceuticals from wastewater. Different degradation rates were observed for the four PhACs studied, and a kinetic model combining steady state concentrations successfully predicted the degradation process of pharmaceuticals.
Article
Public, Environmental & Occupational Health
Li-Fan Liu, Wei-Ming Wang, Jung-Der Wang
Summary: This study aimed to quantify the burdens of disease of stroke survivors receiving LTC in Taiwan by evaluating the outcomes of their utilization including mortality, readmissions, and re-emergency within 1 year after diagnoses of strokes. The results showed that both severe functional impairments and cognitive impairments were important factors for healthcare utilizations among LTC recipients.
FRONTIERS IN PUBLIC HEALTH
(2021)
Review
Cardiac & Cardiovascular Systems
Rod S. Taylor, Hasnain M. Dalal, Ann-Dorthe Zwisler
Summary: Cardiac rehabilitation is often overlooked in the treatment of heart failure. This review provides an update on the evidence, guidelines, and status of cardiac rehabilitation for heart failure patients. It argues that exercise-based rehabilitation is a crucial aspect of heart failure management, alongside medication and medical devices, as it improves patient outcomes, including their quality of life. To improve access and participation, healthcare services should offer heart failure patients a range of evidence-based rehabilitation options, including home-based programs with digital technology and traditional center-based programs, based on disease stage and patient preference.
EUROPEAN HEART JOURNAL
(2023)
Article
Public, Environmental & Occupational Health
Nicole Van Groningen, Ray Duncan, Galen Cook-Wiens, Aaron Kwong, Matthew Sonesen, Teryl K. Nuckols, Suzanne L. Cassel, Joshua M. Pevnick
Summary: The study found that many patients who received interruptive penicillin allergy alerts would likely tolerate penicillin, and half of the alerts were displayed for patients who would likely tolerate another beta-lactam antibiotic.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Medicine, General & Internal
Carl T. Berdahl, An T. Nguyen, Marcio A. Diniz, Andrew J. Henreid, Teryl K. Nuckols, Christopher P. Libby, Joshua M. Pevnick
Summary: By incorporating covariates known to affect body temperature, the study demonstrated improved pretest probability estimates of acute COVID-19 infection. Model 3 showed higher predictive performance, suggesting further validation in a larger, multi-institutional sample is warranted.
Article
Health Care Sciences & Services
Logan T. Murry, Michelle S. Keller, Joshua M. Pevnick, Jeffrey L. Schnipper, Korey A. Kennelty
Summary: This study evaluated pharmacist perceptions of the PHARM-DC intervention using the CFIR framework. The findings suggest that the PHARM-DC intervention can be successfully implemented and that institution-specific contextual factors and pharmacist recommendations should be considered.
BMC HEALTH SERVICES RESEARCH
(2022)
Review
Medical Informatics
Catherine Waldron, Joan Cahill, Sam Cromie, Tim Delaney, Sean P. Kennelly, Joshua M. Pevnick, Tamasine Grimes
Summary: A rapid realist review was conducted to develop theories explaining the impact of Personal Electronic Records of Medications (PERMs) on medication reconciliation at care transitions. Ten provisional theories were identified, relating to design, implementation, and use of PERMs. These theories are interdependent and may collectively impact the effectiveness of PERMs in practice. Further evaluation is needed to test their validity.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2021)
Article
Computer Science, Information Systems
Keith Feldman, Ray G. Duncan, An Nguyen, Galen Cook-Wiens, Yaron Elad, Teryl Nuckols, Joshua M. Pevnick
Summary: This study utilized EHR and Apple Watch data to estimate the proportion of wearers that would benefit from anticoagulation if an AFib diagnosis was made based on wearable device data.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2022)
Article
Obstetrics & Gynecology
Melissa S. Wong, Matthew Wells, Davina Zamanzadeh, Samir Akre, Joshua M. Pevnick, Alex A. T. Bui, Kimberly D. Gregory
Summary: This study developed and validated a machine learning model (Partometer) to predict the probability of vaginal delivery using data obtained during labor from the electronic health record. The study showed that using automated machine learning and intrapartum factors improved the accuracy of predicting the probability of vaginal delivery, and could potentially reduce maternal and neonatal morbidity.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Neal Yuan, Justin Zhang, Rakan Khaki, Derek Leong, Chandrashekhar Bhoopalam, Steven W. Tabak, Yaron Elad, Joshua M. Pevnick, Susan Cheng, Joseph E. Ebinger
Summary: This study assessed the effectiveness of an electronic health records-based safe contrast limit tool in predicting CA-AKI risk and reducing contrast use and CA-AKI. The tool accurately predicted CA-AKI risk and was associated with a decrease in contrast use during percutaneous coronary intervention, but no change in CA-AKI rates.
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2023)
Review
Health Care Sciences & Services
Carl Berdahl, Andrew J. Henreid, Joshua M. Pevnick, Kai Zheng, Teryl K. Nuckols
Summary: This study aimed to identify and characterize digital tools designed to obtain the history of present illness (HPI) directly from patients or caregivers and present this information to clinicians. The study found that the identified tools varied in purpose and functionality, and there was no consensus on how patient-generated information should be collected or presented. Future research should focus on whether these tools can improve patient experience and health outcomes.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Editorial Material
Oncology
Scott A. Mosley, Joshua M. Pevnick
ANNALS OF TRANSLATIONAL MEDICINE
(2022)
Review
Computer Science, Information Systems
Anne M. Walling, Joshua Pevnick, Antonia Bennett, V. G. Vinod Vydiswaran, Christine S. Ritchie
Summary: This study conducted a scoping review of algorithms using electronic health record (EHR) data to identify patients with Alzheimer's disease and related dementias (ADRD) and promote their use in research and clinical care. The results showed that there are various EHR-based phenotypes available for identifying populations with or at high-risk of developing ADRD. This review provides comparative detail to aid in choosing the best algorithm for research, clinical care, and population health projects.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2023)
Article
Medicine, General & Internal
Michelle S. Keller, Johan Carrascoza-Bolanos, Kathleen Breda, Linda Y. Kim, Korey A. Kennelty, Donna W. Leang, Logan T. Murry, Teryl K. Nuckols, Jeffrey L. Schnipper, Joshua M. Pevnick
Summary: This study used implementation science models and qualitative interviews to identify barriers and facilitators to deprescribing benzodiazepines and non-benzodiazepine sedative hypnotics in the hospital. Nurse- and pharmacist-led interventions were found to be appropriate opportunities to initiate deprescribing.
Article
Public, Environmental & Occupational Health
Joshua M. Pevnick, Marcio A. Diniz, Denis Magoffin, Mariko Ishimori, C. Noel Bairey Merz
Summary: The NIH/ORWH SCORE program aims to expedite the development of new knowledge that affects women, understand the etiology of diseases, and foster improved treatment and prevention approaches. The MAE-WEST SCORE focuses on studying inflammatory responses and small vessel aging traits. Through various initiatives, our CEC incorporates consideration of sex as a biological variable (SABV) into our institutional infrastructure.
JOURNAL OF WOMENS HEALTH
(2023)
Article
Health Care Sciences & Services
An T. Nguyen, Jesse Wisniewski, Donna W. Leang, Michelle S. Keller, Sonja Rosen, Rita Shane, Joshua M. Pevnick
Summary: The study evaluated an intervention and found that it significantly reduced the risk of recurrent acute myocardial infarction in women. The intervention consisted of medication therapy and psychological support. These findings contribute to the development and improvement of interventions targeting acute myocardial infarction.
JOURNAL OF MANAGED CARE & SPECIALTY PHARMACY
(2023)
Meeting Abstract
Health Care Sciences & Services
Matthew Modes, Azadeh Dashti, Stuart Finder, Zab Mosenifar, Joshua Pevnick, Margaret Reed, Edward Seferian, Anne Walling, Bradley Rosen
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Meeting Abstract
Geriatrics & Gerontology
A. T. Nguyen, J. Wisniewski, D. Leang, M. S. Keller, S. Rosen, R. Shane, J. Pevnick
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)