Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates

Genetic Tracing via DNGR-1 Expression History Defines Dendritic Cells as a Hematopoietic Lineage

(2013) Barbara U. Schraml et al.   CELL

Evolution of B Cell Responses to Clec9A-Targeted Antigen

(2013) H.-Y. Park et al.   JOURNAL OF IMMUNOLOGY

F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells

(2012) Susan Ahrens et al.   IMMUNITY

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

(2012) Jian-Guo Zhang et al.   IMMUNITY

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

(2012) Santiago Zelenay et al.   JOURNAL OF CLINICAL INVESTIGATION

The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice

(2012) Salvador Iborra et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting Dendritic Cells in vivo for Cancer Therapy

(2012) Irina Caminschi et al.   Frontiers in Immunology

CD103+pulmonary dendritic cells preferentially acquire and present apoptotic cell–associated antigen

(2011) A. Nicole Desch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting Antigen to Mouse Dendritic Cells via Clec9A Induces Potent CD4 T Cell Responses Biased toward a Follicular Helper Phenotype

(2011) M. H. Lahoud et al.   JOURNAL OF IMMUNOLOGY

Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity

(2011) C. Trumpfheller et al.   JOURNAL OF INTERNAL MEDICINE

Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3−/− mice

(2011) Irina Caminschi et al.   MOLECULAR IMMUNOLOGY

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

(2011) J. Idoyaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Boosting antibody responses by targeting antigens to dendritic cells

(2011) Irina Caminschi et al.   TRENDS IN IMMUNOLOGY

Correlates of Protection Induced by Vaccination

(2010) S. A. Plotkin   Clinical and Vaccine Immunology

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A

(2010) Olivier P. Joffre et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Designing Vaccines Based on Biology of Human Dendritic Cell Subsets

(2010) Karolina Palucka et al.   IMMUNITY

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

(2009) David Sancho et al.   NATURE

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

(2008) I. Caminschi et al.   BLOOD

Dendritic cell vaccines in melanoma: From promise to proof?

(2008) W.J. Lesterhuis et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

CLEC9A Is a Novel Activation C-type Lectin-like Receptor Expressed on BDCA3+Dendritic Cells and a Subset of Monocytes

(2008) Cristal Huysamen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

(2008) David Sancho et al.   JOURNAL OF CLINICAL INVESTIGATION