Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC)

Use of ruxolitinib to successfully treat chronic mucocutaneous candidiasis caused by gain-of-function signal transducer and activator of transcription 1 (STAT1) mutation

(2015) Eleanor Higgins et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

New and emerging HDAC inhibitors for cancer treatment

(2014) Alison C. West et al.   JOURNAL OF CLINICAL INVESTIGATION

Matrix Metalloproteinase 13 Expression in Response to Double-Stranded RNA in Human Chondrocytes

(2013) Marta Radwan et al.   ARTHRITIS AND RHEUMATISM

Gain-of-function STAT1 mutations are associated with PD-L1 overexpression and a defect in B-cell survival

(2013) Neil Romberg et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis

(2013) Elizabeth P. Sampaio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Histone deacetylase inhibitors block IFNγ-induced STAT1 phosphorylation

(2012) Torsten Ginter et al.   CELLULAR SIGNALLING

Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis

(2012) Anne Puel et al.   Current Opinion in Allergy and Clinical Immunology

Unravelling fungal immunity through primary immune deficiencies

(2012) Desa Lilic   CURRENT OPINION IN MICROBIOLOGY

JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease

(2012) John J. O'Shea et al.   IMMUNITY

Multigenerational epigenetic adaptation of the hepatic wound-healing response

(2012) Müjdat Zeybel et al.   NATURE MEDICINE

The immediate early genes Fos and Egr1 become STAT1 transcriptional targets in the absence of STAT3

(2011) Davide Schiavone et al.   FEBS LETTERS

Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

(2011) Luyan Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STAT1Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

(2011) Frank L. van de Veerdonk et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impaired TH17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy

(2010) Wan-Fai Ng et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

(2010) Anne Puel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Negative Regulation of Dendritic Cells through Acetylation of the Nonhistone Protein STAT-3

(2009) Yaping Sun et al.   JOURNAL OF IMMUNOLOGY

Phosphorylation–acetylation switch in the regulation of STAT1 signaling

(2009) Oliver H. Krämer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY