Mechanistic basis for the recognition of a misfolded protein by the molecular chaperone Hsp90

Structural Changes Associated with Transthyretin Misfolding and Amyloid Formation Revealed by Solution and Solid-State NMR

(2016) Kwang Hun Lim et al.   BIOCHEMISTRY

Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase

(2016) K. A. Verba et al.   SCIENCE

Chaperones in Neurodegeneration

(2015) I. Lindberg et al.   JOURNAL OF NEUROSCIENCE

Three Turkish families with different transthyretin mutations

(2015) Can Ebru Bekircan-Kurt et al.   NEUROMUSCULAR DISORDERS

Bringing Dynamic Molecular Machines into Focus by Methyl-TROSY NMR

(2014) Rina Rosenzweig et al.   Annual Review of Biochemistry

Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action

(2014) G. Elif Karagöz et al.   CELL

Modulation of the Hsp90 Chaperone Cycle by a Stringent Client Protein

(2014) Oliver Robin Lorenz et al.   MOLECULAR CELL

Proteostasis impairment in protein-misfolding and -aggregation diseases

(2014) Mark S. Hipp et al.   TRENDS IN CELL BIOLOGY

Protein backbone and sidechain torsion angles predicted from NMR chemical shifts using artificial neural networks

(2013) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

Localized Structural Fluctuations Promote Amyloidogenic Conformations in Transthyretin

(2013) Kwang Hun Lim et al.   JOURNAL OF MOLECULAR BIOLOGY

New developments in theATSASprogram package for small-angle scattering data analysis

(2012) Maxim V. Petoukhov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

The Transthyretin Amyloidoses: From Delineating the Molecular Mechanism of Aggregation Linked to Pathology to a Regulatory-Agency-Approved Drug

(2012) Steven M. Johnson et al.   JOURNAL OF MOLECULAR BIOLOGY

A pH-Sensitive, Colorful, Lanthanide-Chelating Paramagnetic NMR Probe

(2012) Wei-Min Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of an Intermediate State in Protein Folding and Aggregation

(2012) P. Neudecker et al.   SCIENCE

Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs

(2011) Steve Bourgault et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transthyretin binds to glucose-regulated proteins and is subjected to endocytosis by the pancreatic β-cell

(2011) Nancy Dekki et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Substrate Binding Drives Large-Scale Conformational Changes in the Hsp90 Molecular Chaperone

(2011) Timothy O. Street et al.   MOLECULAR CELL

Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53

(2011) Franz Hagn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The client protein p53 adopts a molten globule–like state in the presence of Hsp90

(2011) Sung Jean Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Basis for Assembly of Hsp90-Sgt1-CHORD Protein Complexes: Implications for Chaperoning of NLR Innate Immunity Receptors

(2010) Minghao Zhang et al.   MOLECULAR CELL

Gymnastics of Molecular Chaperones

(2010) Matthias P. Mayer   MOLECULAR CELL

N-terminal domain of human Hsp90 triggers binding to the cochaperone p23

(2010) G. E. Karagoz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paramagnetic tagging for protein structure and dynamics analysis

(2010) Peter H.J. Keizers et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility

(2009) Pablo C. Echeverria et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Molecular Chaperone Hsp90 Modulates Intermediate Steps of Amyloid Assembly of the Parkinson-related Protein α-Synuclein

(2009) S. Fabio Falsone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design, Synthesis, and Evaluation of a Lanthanide Chelating Protein Probe: CLaNP-5 Yields Predictable Paramagnetic Effects Independent of Environment

(2008) Peter H. J. Keizers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multiple Conformations of E. coli Hsp90 in Solution: Insights into the Conformational Dynamics of Hsp90

(2008) Kristin A. Krukenberg et al.   STRUCTURE