Pathogenic functions of B cells in autoimmune diseases: IFN-γ production joins the criminal gang

B cells expressing IFN-γ suppress Treg-cell differentiation and promote autoimmune experimental arthritis

(2015) Susan A. Olalekan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

B-cell inhibition by cross-linking CD79b is superior to B-cell depletion with anti-CD20 antibodies in treating murine collagen-induced arthritis

(2014) Hilke Brühl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Suppression of Proteoglycan-Induced Arthritis by Anti-CD20 B Cell Depletion Therapy Is Mediated by Reduction in Autoantibodies and CD4+ T Cell Reactivity

(2014) K. Hamel et al.   JOURNAL OF IMMUNOLOGY

TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity

(2014) V. Lampropoulou et al.   JOURNAL OF IMMUNOLOGY

Development of Proteoglycan-Induced Arthritis Is Independent of IL-17

(2014) P. D. Doodes et al.   JOURNAL OF IMMUNOLOGY

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

Identification of IFN-γ-producing innate B cells

(2013) Yan Bao et al.   CELL RESEARCH

The effect of B-cell depletion therapy on serological evidence of B-cell and plasmablast activation in patients with rheumatoid arthritis over multiple cycles of rituximab treatment

(2013) G. Cambridge et al.   JOURNAL OF AUTOIMMUNITY

MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

(2013) Nicolas Molnarfi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tolerant Anti-Insulin B Cells Are Effective APCs

(2013) P. L. Kendall et al.   JOURNAL OF IMMUNOLOGY

B Cell-Specific Expression of Inducible Costimulator Ligand Is Necessary for the Induction of Arthritis in Mice

(2013) Keith M. Hamel et al.   Arthritis & Rheumatology

Increased Frequency of Circulating Follicular Helper T Cells in Patients with Rheumatoid Arthritis

(2012) Jie Ma et al.   Clinical & Developmental Immunology

B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells

(2012) Tom A. Barr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse

(2012) Katja Lüthje et al.   NATURE IMMUNOLOGY

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: Results of a phase II, randomized, placebo-controlled trial

(2011) R. F. van Vollenhoven et al.   ARTHRITIS AND RHEUMATISM

B Cell Depletion Enhances T Regulatory Cell Activity Essential in the Suppression of Arthritis

(2011) K. M. Hamel et al.   JOURNAL OF IMMUNOLOGY

TLR and B Cell Receptor Signals to B Cells Differentially Program Primary and Memory Th1 Responses to Salmonella enterica

(2010) T. A. Barr et al.   JOURNAL OF IMMUNOLOGY

Cytokine-Producing Effector B Cells Regulate Type 2 Immunity to H. polygyrus

(2009) Wojciech Wojciechowski et al.   IMMUNITY

Cytokine-secreting follicular T cells shape the antibody repertoire

(2009) R Lee Reinhardt et al.   NATURE IMMUNOLOGY

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rituximab in relapsing-remitting multiple sclerosis: A 72-week, open-label, phase I trial

(2008) Amit Bar-Or et al.   ANNALS OF NEUROLOGY