The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3

Prognostic Value of Pentraxin-3 Level in Patients with STEMI and Its Relationship with Heart Failure and Markers of Oxidative Stress

(2015) Marie Tomandlova et al.   DISEASE MARKERS

Ubiquitin-Like Protein ISG15 (Interferon-Stimulated Gene of 15 kDa) in Host Defense Against Heart Failure in a Mouse Model of Virus-Induced Cardiomyopathy

(2014) Anna Rahnefeld et al.   CIRCULATION

Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation

(2014) Michele Mishto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PTX3: A modulator of human coronary plaque vulnerability acting by macrophages type 2

(2014) S. Pucci et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses

(2014) P. C. Reading et al.   JOURNAL OF IMMUNOLOGY

In Vivo Ablation of Type I Interferon Receptor from Cardiomyocytes Delays Coxsackieviral Clearance and Accelerates Myocardial Disease

(2014) N. Althof et al.   JOURNAL OF VIROLOGY

Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding

(2014) Marcelino Arciniega et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunoproteasomes Are Important for Proteostasis in Immune Responses

(2013) Frédéric Ebstein et al.   CELL

Innate Immune Interleukin-1 Receptor–Associated Kinase 4 Exacerbates Viral Myocarditis by Reducing CCR5 + CD11b + Monocyte Migration and Impairing Interferon Production

(2013) Alan Valaperti et al.   CIRCULATION

Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

(2012) Eva M. Huber et al.   CELL

Revisiting the role of the immunoproteasome in the activation of the canonical NF-κB pathway

(2012) Eun Ryoung Jang et al.   Molecular BioSystems

Antigen-presentation capacity of dendritic cells is impaired in ongoing enterovirus myocarditis

(2011) Anna Rahnefeld et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans

(2011) Akiko Kitamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Myocarditis

(2011) Sandeep Sagar et al.   LANCET

Mice completely lacking immunoproteasomes show major changes in antigen presentation

(2011) Eleanor Z Kincaid et al.   NATURE IMMUNOLOGY

Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome

(2011) K. Arima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impairment of Immunoproteasome Function by β5i/LMP7 Subunit Deficiency Results in Severe Enterovirus Myocarditis

(2011) Elisa Opitz et al.   PLoS Pathogens

PTX3 expression in the heart tissues of patients with myocardial infarction and infectious myocarditis

(2010) Manuela Nebuloni et al.   CARDIOVASCULAR PATHOLOGY

Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress

(2010) Ulrike Seifert et al.   CELL

Pentraxins in innate immunity: lessons from PTX3

(2010) Livija Deban et al.   CELL AND TISSUE RESEARCH

Targeting the proteasome: partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis

(2010) N. Schmidt et al.   GUT

Unexpected Role for the Immunoproteasome Subunit LMP2 in Antiviral Humoral and Innate Immune Responses

(2010) S. E. Hensley et al.   JOURNAL OF IMMUNOLOGY

Prevention of Experimental Colitis by a Selective Inhibitor of the Immunoproteasome

(2010) M. Basler et al.   JOURNAL OF IMMUNOLOGY

Regulation of leukocyte recruitment by the long pentraxin PTX3

(2010) Livija Deban et al.   NATURE IMMUNOLOGY

Differential Interferon Responses Enhance Viral Epitope Generation by Myocardial Immunoproteasomes in Murine Enterovirus Myocarditis

(2009) Sandra Jäkel et al.   AMERICAN JOURNAL OF PATHOLOGY

Generation of in silico predicted coxsackievirus B3-derived MHC class I epitopes by proteasomes

(2009) Antje Voigt et al.   AMINO ACIDS

Viral Myocarditis

(2009) Toshitaka Yajima et al.   CIRCULATION

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

(2009) Tony Muchamuel et al.   NATURE MEDICINE

Myocarditis

(2009) Leslie T. Cooper   NEW ENGLAND JOURNAL OF MEDICINE

Cardioprotective Function of the Long Pentraxin PTX3 in Acute Myocardial Infarction

(2008) Monica Salio et al.   CIRCULATION

Predictors of Outcome in Patients With Suspected Myocarditis

(2008) Ingrid Kindermann et al.   CIRCULATION

Antitopes Define Preferential Proteasomal Cleavage Site Usage

(2008) Britta Strehl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pentraxin 3, a new marker for vascular inflammation, predicts adverse clinical outcomes in patients with heart failure

(2007) Satoshi Suzuki et al.   AMERICAN HEART JOURNAL