Article
Biochemistry & Molecular Biology
Gabriela Rios Martini, Ekaterina Tikhonova, Elisa Rosati, Meghan Bialt Decelie, Laura Katharina Sievers, Florian Tran, Matthias Lessing, Arne Bergfeld, Sophia Hinz, Susanna Nikolaus, Julia Kuempers, Anna Matysiak, Philipp Hofmann, Carina Saggau, Stephan Schneiders, Ann-Kristin Kamps, Gunnar Jacobs, Wolfgang Lieb, Jochen Maul, Britta Siegmund, Barbara Seegers, Holger Hinrichsen, Hans-Heinrich Oberg, Daniela Wesch, Stefan Bereswill, Markus M. Heimesaat, Jan Rupp, Olaf Kniemeyer, Axel A. Brakhage, Sascha Brunke, Bernhard Hube, Konrad Aden, Andre Franke, Iliyan D. Iliev, Alexander Scheffold, Stefan Schreiber, Petra Bacher
Summary: Aberrant CD4(+) T cell reactivity against intestinal microorganisms is thought to drive mucosal inflammation in inflammatory bowel diseases. This study identifies yeasts as direct activators of altered CD4(+) T cell reactions in patients with Crohn's disease, revealing their potential role in chronic activation of inflammatory immune responses.
Review
Food Science & Technology
Lohith Kunyeit, Reeta P. Rao, K. A. Anu-Appaiah
Summary: Yeasts derived from fermented foods have various characteristics, such as larger cells, a rigid cell wall composed primarily of glucans and mannans, natural resistance to antibiotics, and the secretion of beneficial secondary metabolites. This review also focuses on the therapeutic applications of probiotic yeasts from fermented foods in treating Candida-associated infections and preventing health complications caused by opportunistic fungal colonization, including drug-resistant superbugs.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Food Science & Technology
Wendy Franco, Sergio Benavides, Pedro Valencia, Cristian Ramirez, Alejandra Urtubia
Summary: This study characterized the yeast and LAB in seven grape cultivars cultivated in Chile, revealing a diversity of non-Saccharomyces yeasts in different grape varieties. The fermentation process also showed that some yeast species have a high tolerance to environments rich in ethanol.
Article
Food Science & Technology
Kai Chen, Chang Liu, Yingxiang Wang, Zichen Wang, Fangkun Li, Liyan Ma, Jingming Li
Summary: Salt maceration and sugar addition in traditional fermentation impact greengage skin cells; non-Saccharomyces yeasts dominate the entire fermentation process as indicated by high-throughput sequencing technology; highly correlated to the evolution of volatile compounds in greengage wine.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Food Science & Technology
Adam Staniszewski, Monika Kordowska-Wiater
Summary: One approach to maintaining a healthy microbiota in the human gastrointestinal tract is through the consumption of probiotics. This study examined the probiotic potential of yeast strains isolated from Polish wines. The tested strains belonged to six different species and were evaluated for their probiotic properties, safety, enzymatic activity, and antioxidant properties. The results showed that certain strains of H. uvarum, M. pulcherrima, and S. cerevisiae exhibited promising probiotic characteristics.
Article
Food Science & Technology
Camelia Filofteia Diguta, Constanta Mihai, Radu Cristian Toma, Carmen Cimpeanu, Florentina Matei
Summary: This study aimed to investigate the probiotic potential of three yeast strains isolated from agro-food natural sources, comparing them with a reference Saccharomyces boulardii. The yeast strains showed tolerance to different temperatures, salt concentrations, and pH ranges. S. cerevisiae BB06 exhibited strong antagonistic activity, high auto-aggregation ability, good surface hydrophobicity, and excellent antioxidant properties. The yeast strains also demonstrated resistance to antibacterial antibiotics and high survival rates during freeze-drying. Among them, S. cerevisiae BB06 was found to have valuable probiotic traits.
Review
Engineering, Chemical
Massimo Iorizzo, Francesca Coppola, Francesco Letizia, Bruno Testa, Elena Sorrentino
Summary: In the beer industry today, the quality of beer is closely tied to the fermentation activity of yeasts, with researchers and brewers now focusing on selecting new yeast strains with specific technological and metabolic characteristics to meet the growing demand for innovative and specialty beers. Saccharomyces and non-Saccharomyces yeasts are being used in brewing to produce beers with unique properties, highlighting a new biotechnological approach in the field of beer production.
Article
Multidisciplinary Sciences
Xin Li, Irina Leonardi, Gregory G. Putzel, Alexa Semon, William D. Fiers, Takato Kusakabe, Woan-Yu Lin, Iris H. Gao, Itai Doron, Alejandra Gutierrez-Guerrero, Meghan B. DeCelie, Guilhermina M. Carriche, Marissa Mesko, Chen Yang, Julian R. Naglik, Bernhard Hube, Ellen J. Scherl, Iliyan D. Iliev
Summary: The study reveals the rich genetic diversity of pathogenic Candida albicans strains in the colonic mucosa of patients with inflammatory bowel disease, with some strains having high immune-cell-damaging capacity (HD strains). These strains exacerbate intestinal inflammation in vivo through specific mechanisms, highlighting new insights into host-fungal interactions and potential diagnostic and therapeutic targets for inflammatory diseases.
Article
Infectious Diseases
Nicole L. Belanger, Su Jeoung Kim, Paulo J. M. Bispo
Summary: Candida species are the most common pathogens responsible for ocular infections in temperate regions of the world. This study sequenced and molecularly characterized Candida species isolated from patients with eye infections to understand their distribution over time.
Review
Food Science & Technology
Patrizia Romano, Giacomo Braschi, Gabriella Siesto, Francesca Patrignani, Rosalba Lanciotti
Summary: The aromatic complexity of wine is mainly influenced by the interaction between grapes and fermentation agents, with yeast playing a crucial role in the formation of aroma compounds. Yeast can contribute to the formation of compounds from primary metabolism, synthesis of specific metabolites, and modification of molecules present in the must.
Review
Food Science & Technology
Ana Mencher, Pilar Morales, Jordi Tronchoni, Ramon Gonzalez
Summary: The development of non-Saccharomyces starter cultures in oenology has led to increasing interest in the interactions between microorganisms during the transformation of grape must into wine. Interspecific interactions between wine yeasts involve various levels of competition and metabolic exchange, with indications of specific recognition in some cases. This article discusses the communication mechanisms between wine yeasts during alcoholic fermentation.
Article
Biochemical Research Methods
Pedro A. Baldera-Aguayo, Arden Lee, Virginia W. Cornish
Summary: Antibiotic resistance is a global health threat, and developing new tetracycline analogue therapeutics is urgent. By engineering yeast, researchers have successfully produced the fungal tetracycline TAN-1612 and significantly increased its yield. This study marks an important step in combating antibiotic resistance.
ACS SYNTHETIC BIOLOGY
(2022)
Review
Microbiology
Hao Li, Ming-xing Miao, Cheng-lin Jia, Yong-bing Cao, Tian-hua Yan, Yuan-ying Jiang, Feng Yang
Summary: This review focuses on the interactions between Candida albicans and the host microbiota in the mouth, gut, blood, and vagina, and highlights important future research directions. Evaluating these interactions will contribute to a better understanding of the etiology of fungal infections and provide new insights for therapeutic approaches.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Microbiology
Sergi Maicas, Jose Juan Mateo
Summary: Drinking wine provides high nutritional and health benefits. However, using only one type of yeast in the fermentation process may result in a wine lacking aroma and flavor. Non-Saccharomyces yeasts contribute to the taste and aroma of wine, enhancing the complexity and enjoyment of the drinking experience.
Article
Genetics & Heredity
Yiwei Liu, Zhongyao Chen, Jingyuan Li, Zhiqing Zhu, Sibei Pang, Jianping Xu, Jinyan Wu
Summary: Yeasts play important roles in both the environment and in human welfare. This study characterized yeast diversity in tropical environments of China and found that some environmental yeasts were known human pathogens. Additionally, a significant number of yeast isolates showed resistance or intermediate susceptibility to the commonly used antifungal drug fluconazole.
Article
Integrative & Complementary Medicine
Vibha Malhotra, Joanna Harnett, Erica McIntyre, Amie Steel, Keith Wong, Bandana Saini
Summary: This study explores the differences in disclosure rates and reasons for disclosing either conventional or complementary medicine use to healthcare practitioners between individuals with sleep disorders and those without. The results indicate that individuals with sleep disorders are more likely to disclose their use of complementary medicine and have concerns about drug interactions. This suggests the need for further research on the expectations of individuals with sleep disorders regarding healthcare practitioners' knowledge of complementary medicine and drug interactions, as well as the knowledge of complementary medicine practitioners regarding conventional medicine.
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2022)
Review
Education, Scientific Disciplines
Clare Carter, Joanna E. Harnett, Ines Krass, Ingrid C. Gelissen
Summary: This study reviewed the perspectives and opinions of primary healthcare practitioners in Australia and New Zealand on their role in nutrition counselling. The findings showed that healthcare practitioners acknowledged the importance of providing dietary advice to patients but faced challenges such as insufficient education and training, time constraints, and limited knowledge and confidence.
INTERNATIONAL JOURNAL OF MEDICAL EDUCATION
(2022)
Article
Medicine, General & Internal
Joanna E. Harnett, Shane Desselle, Carolina Oi Lam Ung
Summary: This study aims to identify an international set of core responsibilities that support pharmacists' contribution in ensuring the quality and safe use of T&CMs to promote public health.
Review
Anesthesiology
Katherine Y. C. Cheng, Joanna E. Harnett, Sharon R. Davis, Daniela Eassey, Susan Law, Lorraine Smith
Summary: The attitudes of healthcare professionals towards the clinical use of medicinal cannabis (MC) for chronic pain are not well understood. This review aims to identify and synthesize existing evidence on this topic. The findings suggest that healthcare professionals require education, training, and clinical guidelines to support the best practice in the use of MC for chronic pain.
Review
Nutrition & Dietetics
Rene Erhardt, Joanna E. Harnett, Elizabeth Steels, Kathryn J. Steadman
Summary: Functional constipation is a significant global health issue, and the composition of the gut microbiota may play a role in its development. Prebiotics, as a non-pharmaceutical treatment, have been extensively studied, but their efficacy and impact on the microbiota remain controversial.
BRITISH JOURNAL OF NUTRITION
(2022)
Review
Oncology
Wai-Jo Jocelin Chan, Jeffry Adiwidjaja, Andrew J. McLachlan, Alan V. Boddy, Joanna E. Harnett
Summary: Natural products, such as dietary supplements and health supplements, are commonly used by cancer patients to improve quality of life and reduce treatment side effects. However, there is concern that the concurrent use of these products with cancer treatments can lead to adverse effects and unintended treatment outcomes. Limited research suggests that some natural products may interact with common cancer treatments, while others may actually reduce side effects. Further investigation is needed in this area.
CANCER CHEMOTHERAPY AND PHARMACOLOGY
(2023)
Article
Oncology
Andrew Croaker, Lei Liu, Stephen P. P. Myers
Summary: This study is a large national retrospective case series on the use of black salve treatment, revealing high rates of cancer persistence in the treated areas. It also found that patients are applying black salve to benign lesions and lesions in cosmetically sensitive areas, and rural patients have higher proportional rates of black salve use. Current Australian black salve public health initiatives are failing.
INTEGRATIVE CANCER THERAPIES
(2023)
Article
Biochemistry & Molecular Biology
Bassam S. M. Al Kazman, Joanna Elizabeth Harnett, Jane Rouse Hanrahan
Summary: Annonaceae is a large family with more than 119 genera and 2500 species, distributed in tropical and subtropical areas. Annona genus consists of about 175 species, mainly found in Brazil and tropical America. This study investigates the constituents of A. atemoya leaves, fruit pulp, and seeds, as few studies have reported them. Annonaceous acetogenins were identified for the first time in the leaves and pulp of A. atemoya. Twenty compounds, including sixteen acetogenins and four alkaloids, were identified. The highest concentrations and greatest diversity of compounds were found in the seeds.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Joanna Harnett, Erica McIntyre, Jon Adams, Tamia Addison, Holly Bannerman, Lucy Egelton, Jessica Ma, Leon Zabakly, Amie Steel
Summary: This study found that nearly half of Australians use complementary medicine (CM) products, with half of them frequently or always using CM products on the same day as prescription medications. Older individuals, those with lower education levels, and those with chronic illnesses are more likely to concurrently use CM products and other medications. Overall, the prevalence and characteristics of CM use in the Australian population are similar to data collected five years ago. This study highlights the need for further research to ensure appropriate and safe use of CM products among older and more vulnerable populations.
Article
Orthopedics
Sharon Erdrich, Jason A. Hawrelak, Stephen P. Myers, Momchilo Vuyisich, Joanna E. Harnett
Summary: This is a prospective study examining the interactions between digestive function, human gene expression, and the gut microbiome in relation to fibromyalgia. The study aims to gather data and samples to explore factors associated with fibromyalgia, with the goal of improving management of this condition.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Review
Public, Environmental & Occupational Health
Joanna E. Harnett, Carolina Oi Lam Ung
Summary: A review was conducted to explore the willingness of community pharmacists to provide counseling on the appropriate and safe use of traditional and complementary medicines (T&CM). Multiple barriers were identified, including a lack of clear role definition. The review aimed to update and extend these findings by identifying studies published since 2015 that focused on pharmacists in any setting.
RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY
(2023)
Article
Integrative & Complementary Medicine
Andrew Croaker, Arie Davis, Anthony Carroll, Lei Liu, Stephen P. Myers
Summary: Black salve is a controversial complementary and alternative medicine (CAM) associated with skin toxicity and cancer treatment failures. This study found that the alkaloids present in black salve have synergistic cytotoxicity against skin cancer cell lines, providing valuable information for potential therapeutic applications.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2022)
Review
Nutrition & Dietetics
Joanna Harnett, Mike Climstein, Joe Walsh, Janelle Gifford
Summary: The prevalence of chronic conditions in Masters athletes is high, with common conditions including hypertension, hyperlipidemia, asthma, osteoarthritis, depression, and anxiety. Many of these conditions require medication treatment. However, there is also a high prevalence of dietary supplement usage among Masters athletes, which raises concerns about potential drug-nutrient interactions.
CURRENT NUTRITION REPORTS
(2022)
Article
Integrative & Complementary Medicine
Adam Sadowski, Ryan S. Wexler, Douglas Hanes, Lita Buttolph, Tediana Torrens, Jillian Moehle, Hadil Sarrar, Joanna Harnett, David T. Zava, Ryan Bradley
Summary: This study aimed to evaluate the associations between perceived stress, sleep disturbance, and meditative practices with diurnal salivary free cortisol, and the associations of meditative practices as well as mind-body practices with perceived stress and sleep disturbance. The study found that greater sleep disturbance was independently associated with increased daytime cortisol, while perceived stress and meditative practices were not associated with cortisol levels.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2022)
