Vascular endothelial growth factor-B: Impact on physiology and pathology

Expression, purification and characterization of a vascular endothelial growth factor fusion protein

(2016) Yu Zhang et al.   BIOTECHNOLOGY LETTERS

Expression of vascular endothelial growth factor (VEGF)-B and its receptor (VEGFR1) in murine heart, lung and kidney

(2016) Lars Muhl et al.   CELL AND TISSUE RESEARCH

VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications

(2016) Marius R. Robciuc et al.   Cell Metabolism

PGC-1α Coordinates Mitochondrial Respiratory Capacity and Muscular Fatty Acid Uptake via Regulation of VEGF-B

(2016) Annika Mehlem et al.   DIABETES

Dual effects of VEGF-B on activating cardiomyocytes and cardiac stem cells to protect the heart against short- and long-term ischemia–reperfusion injury

(2016) Guo-hua Li et al.   Journal of Translational Medicine

Non-alcoholic fatty liver disease and diabetes

(2016) Jonathan M. Hazlehurst et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Metformin potentiates anti-tumor effect of resveratrol on pancreatic cancer by down-regulation of VEGF-B signaling pathway

(2016) Mengmeng Zhu et al.   Oncotarget

Endothelial Cell Metabolism in Normal and Diseased Vasculature

(2015) Guy Eelen et al.   CIRCULATION RESEARCH

Adipose VEGF Links the White-to-Brown Fat Switch With Environmental, Genetic, and Pharmacological Stimuli in Male Mice

(2015) Matthew J. During et al.   ENDOCRINOLOGY

VEGF-B promotes cancer metastasis through a VEGF-A–independent mechanism and serves as a marker of poor prognosis for cancer patients

(2015) Xiaojuan Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGF-B: a more balanced approach toward cardiac neovascularization?

(2014) C. Kupatt et al.   EMBO Molecular Medicine

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice

(2014) M. H. Dijkstra et al.   Scientific Reports

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

(2013) Irina M. Jaba et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson’s disease

(2013) X. Yue et al.   NEUROSCIENCE

Bladder Preservation Therapy for Muscle-Invading Bladder Cancers on Radiation Therapy Oncology Group Trials 8802, 8903, 9506, and 9706: Vascular Endothelial Growth Factor B Overexpression Predicts for Increased Distant Metastasis and Shorter Survival

(2013) T. Lautenschlaeger et al.   ONCOLOGIST

Endothelial Fatty Acid Transport: Role of Vascular Endothelial Growth Factor B

(2013) Carolina Hagberg et al.   PHYSIOLOGY

Diabetes Mellitus and the β Cell: The Last Ten Years

(2012) Frances M. Ashcroft et al.   CELL

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Treating Diabetes by Blocking a Vascular Growth Factor

(2012) Peter Carmeliet et al.   Cell Metabolism

High Oxidative Capacity Due to Chronic Exercise Training Attenuates Lipid-Induced Insulin Resistance

(2012) E. Phielix et al.   DIABETES

Enhanced recovery from ischemia–reperfusion injury in PI3Kα dominant negative hearts: Investigating the role of alternate PI3K isoforms, increased glucose oxidation and MAPK signaling

(2012) Brent A. McLean et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

(2012) Carolina E. Hagberg et al.   NATURE

Comparing protein VEGF inhibitors: In vitro biological studies

(2011) Lanlan Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol

(2011) E. L. Lim et al.   DIABETOLOGIA

Vascular endothelial growth factor-B is neuroprotective in an in vivo rat model of Parkinson's disease

(2011) Torsten Falk et al.   NEUROSCIENCE LETTERS

Targeting EGFR and VEGF(R) pathway cross-talk in tumor survival and angiogenesis

(2011) Annette K. Larsen et al.   PHARMACOLOGY & THERAPEUTICS

Consistency of the Disposition Index in the Face of Diet Induced Insulin Resistance: Potential Role of FFA

(2011) Darko Stefanovski et al.   PLoS One

The cardiokine story unfolds: ischemic stress-induced protein secretion in the heart

(2011) Shirin Doroudgar et al.   TRENDS IN MOLECULAR MEDICINE

Complicated life, complicated VEGF-B

(2011) Xuri Li et al.   TRENDS IN MOLECULAR MEDICINE

Vascular endothelial growth factor-B gene transfer prevents angiotensin II-induced diastolic dysfunction via proliferation and capillary dilatation in rats

(2010) Raisa Serpi et al.   CARDIOVASCULAR RESEARCH

VEGF-B: a thing of beauty

(2010) Xuri Li   CELL RESEARCH

Vascular Endothelial Growth Factor-B Acts as a Coronary Growth Factor in Transgenic Rats Without Inducing Angiogenesis, Vascular Leak, or Inflammation

(2010) Maija Bry et al.   CIRCULATION

Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca2+ Channels From Secretory Vesicles

(2010) S. C. Collins et al.   DIABETES

Cotransfection of Vascular Endothelial Growth Factor-A and Platelet-Derived Growth Factor-B Via Recombinant Adeno-Associated Virus Resolves Chronic Ischemic Malperfusion

(2010) Christian Kupatt et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Lipid-induced insulin resistance: unravelling the mechanism

(2010) Varman T Samuel et al.   LANCET

Vascular endothelial growth factor B controls endothelial fatty acid uptake

(2010) Carolina E. Hagberg et al.   NATURE

Suppressive Effects of Vascular Endothelial Growth Factor-B on Tumor Growth in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis

(2010) Imke Albrecht et al.   PLoS One

VEGF-B

(2010) Xuri Li et al.   Cell Adhesion & Migration

The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice

(2009) Jenni Huusko et al.   CARDIOVASCULAR RESEARCH

Chronic Palmitate Exposure Inhibits Insulin Secretion by Dissociation of Ca2+ Channels from Secretory Granules

(2009) Michael B. Hoppa et al.   Cell Metabolism

Vascular Endothelial Growth Factor-B Induces Myocardium-Specific Angiogenesis and Arteriogenesis via Vascular Endothelial Growth Factor Receptor-1– and Neuropilin Receptor-1–Dependent Mechanisms

(2009) Johanna E. Lähteenvuo et al.   CIRCULATION

VEGFs and receptors involved in angiogenesis versus lymphangiogenesis

(2009) Marja Lohela et al.   CURRENT OPINION IN CELL BIOLOGY

Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction

(2009) Lorena Zentilin et al.   FASEB JOURNAL

Structure and function of VEGF receptors

(2009) Edward Stuttfeld et al.   IUBMB LIFE

Vascular endothelial growth factor B (VEGF-B) is up-regulated and exogenous VEGF-B is neuroprotective in a culture model of Parkinson's disease

(2009) Torsten Falk et al.   Molecular Neurodegeneration

Reevaluation of the Role of VEGF-B Suggests a Restricted Role in the Revascularization of the Ischemic Myocardium

(2008) Xuri Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy

(2008) Terhi Karpanen et al.   CIRCULATION RESEARCH

Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells

(2008) Hewang Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment

(2008) Philip Leonard et al.   JOURNAL OF MOLECULAR BIOLOGY

Novel Role for Vascular Endothelial Growth Factor (VEGF) Receptor-1 and Its Ligand VEGF-B in Motor Neuron Degeneration

(2008) K. Poesen et al.   JOURNAL OF NEUROSCIENCE

Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters

(2008) Mitsuro Kanda et al.   JOURNAL OF SURGICAL ONCOLOGY

DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes

(2007) Carolyn et al.   Frontiers in Bioscience-Landmark