4.6 Article

Real time complete Stokes polarimetric imager based on a linear polarizer array camera for tissue polarimetric imaging

期刊

BIOMEDICAL OPTICS EXPRESS
卷 8, 期 11, 页码 4933-4946

出版社

OPTICAL SOC AMER
DOI: 10.1364/BOE.8.004933

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资金

  1. ERC [242991]
  2. National Institute of Health Research i4i award [II-LB-0214-20009]
  3. European Research Council (ERC) [242991] Funding Source: European Research Council (ERC)
  4. National Institutes of Health Research (NIHR) [II-LB-0214-20009] Funding Source: National Institutes of Health Research (NIHR)
  5. National Institute for Health Research [II-LB-0214-20009] Funding Source: researchfish

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Tissue polarimetric imaging measures Mueller matrices of tissues or Stokes vectors of the emergent light from tissues (normally using incidence with a fixed polarization state) over a field of view, and has demonstrated utility in a number of surgical and diagnostic applications. Here we introduce a compact complete Stokes polarimetric imager that can work for multiple wavelength bands with a frame-rate suitable for real-time applications. The imager was validated with standard polarizing components, and then employed as a polarization state analyzer of a Mueller imaging polarimeter and a standalone Stokes imaging polarimeter respectively to image the process of dehydration of bovine tendon tissue. The results obtained in this work suggested that the polarization properties of the samples rich of collagen fibres can change with the degree of dehydration, and therefore, dehydration of the samples preparedfor polarimetric imaging (e.g. polarimetric microscopy) should be carefully controlled. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License.

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