Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia
出版年份 2017 全文链接
标题
Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia
作者
关键词
-
出版物
Nature Communications
Volume 8, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-07-21
DOI
10.1038/s41467-017-00210-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice
- (2016) G. Knittel et al. BLOOD
- The 2016 revision of the World Health Organization classification of lymphoid neoplasms
- (2016) S. H. Swerdlow et al. BLOOD
- Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia
- (2016) Andrew W. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cytogenetic and Flow Cytometry Evaluation of Richter Syndrome Reveals MYC, CDKN2A, IGH Alterations With Loss of CD52, CD62L and Increase of CD71 Antigen Expression as the Most Frequent Recurrent Abnormalities
- (2015) Renata Woroniecka et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatment
- (2015) Michael Hallek AMERICAN JOURNAL OF HEMATOLOGY
- Advances in first-line treatment of chronic lymphocytic leukemia: current recommendations on management and first-line treatment by the German CLL Study Group (GCLLSG)
- (2015) Paula Cramer et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Randomized, Double-Blind Phase II Trial With Prospective Classification by ATM Protein Level to Evaluate the Efficacy and Tolerability of Olaparib Plus Paclitaxel in Patients With Recurrent or Metastatic Gastric Cancer
- (2015) Yung-Jue Bang et al. JOURNAL OF CLINICAL ONCOLOGY
- Mutations driving CLL and their evolution in progression and relapse
- (2015) Dan A. Landau et al. NATURE
- KEGG as a reference resource for gene and protein annotation
- (2015) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Targeting ATM-deficient CLL through interference with DNA repair pathways
- (2015) Gero Knittel et al. Frontiers in Genetics
- Mouse models in the study of chronic lymphocytic leukemia pathogenesis and therapy
- (2014) G. Simonetti et al. BLOOD
- Molecular Pathways: Exploiting Tumor-Specific Molecular Defects in DNA Repair Pathways for Precision Cancer Therapy
- (2014) F. Dietlein et al. CLINICAL CANCER RESEARCH
- Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia
- (2014) Richard R. Furman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches
- (2014) Felix Dietlein et al. TRENDS IN GENETICS
- A Functional Cancer Genomics Screen Identifies a Druggable Synthetic Lethal Interaction between MSH3 and PRKDC
- (2014) F. Dietlein et al. Cancer Discovery
- Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
- (2013) Dan A. Landau et al. CELL
- ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition
- (2013) Maria Gilardini Montani et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome
- (2013) Giulia Fabbri et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mechanisms of Intracerebral Lymphoma Growth Delineated in a Syngeneic Mouse Model of Central Nervous System Lymphoma
- (2013) Manuel Montesinos-Rongen et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Loss of p53 and altered miR15-a/16-1→MCL-1 pathway in CLL: insights from TCL1-Tg:p53 −/− mouse model and primary human leukemia cells
- (2013) J Liu et al. LEUKEMIA
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response
- (2013) H. Christian Reinhardt et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
- (2013) John C. Byrd et al. NEW ENGLAND JOURNAL OF MEDICINE
- Sister chromatid exchanges occur in G2-irradiated cells
- (2011) Sandro Conrad et al. CELL CYCLE
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
- (2011) Víctor Quesada et al. NATURE GENETICS
- The role of homologous recombination in radiation-induced double-strand break repair
- (2011) Penny A. Jeggo et al. RADIOTHERAPY AND ONCOLOGY
- The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo
- (2010) V. J. Weston et al. BLOOD
- Allogeneic stem cell transplantation provides durable disease control in poor-risk chronic lymphocytic leukemia: long-term clinical and MRD results of the German CLL Study Group CLL3X trial
- (2010) P. Dreger et al. BLOOD
- The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax
- (2010) Aaron A. Goodarzi et al. DNA REPAIR
- Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
- (2010) Andrew Tutt et al. LANCET
- Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial
- (2010) M Hallek et al. LANCET
- ATM Deficiency Sensitizes Mantle Cell Lymphoma Cells to Poly(ADP-Ribose) Polymerase-1 Inhibitors
- (2010) C. T. Williamson et al. MOLECULAR CANCER THERAPEUTICS
- Prognostic factors in chronic lymphocytic leukemia—what do we need to know?
- (2010) Paula Cramer et al. Nature Reviews Clinical Oncology
- Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2
- (2009) H Christian Reinhardt et al. CURRENT OPINION IN CELL BIOLOGY
- ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
- (2009) Andrea Beucher et al. EMBO JOURNAL
- Highly B lymphocyte-specific tamoxifen inducible transgene expression of CreERT2by using the LC-1 locus BAC vector
- (2009) Peter Boross et al. GENESIS
- Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
- (2008) M. Hallek et al. BLOOD
- ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin
- (2008) Aaron A. Goodarzi et al. MOLECULAR CELL
- IMGT(R), the international ImMunoGeneTics information system(R)
- (2008) M.-P. Lefranc et al. NUCLEIC ACIDS RESEARCH
- Complementary functions of ATM and H2AX in development and suppression of genomic instability
- (2008) S. Zha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search