An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells

Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells

(2016) Felix C. Giani et al.   Cell Stem Cell

Comparison of the Proteome of Adult and Cord Erythroid Cells, and Changes in the Proteome Following Reticulocyte Maturation

(2016) Marieangela C. Wilson et al.   MOLECULAR & CELLULAR PROTEOMICS

Autophagic vesicles on mature human reticulocytes explain phosphatidylserine-positive red cells in sickle cell disease

(2015) T. J. Mankelow et al.   BLOOD

Rh D blood group conversion using transcription activator-like effector nucleases

(2015) Young-Hoon Kim et al.   Nature Communications

Global superstructure optimisation of red blood cell production in a parallelised hollow fibre bioreactor

(2014) Ruth Misener et al.   COMPUTERS & CHEMICAL ENGINEERING

The cytoskeletal binding domain of band 3 is required for multiprotein complex formation and retention during erythropoiesis

(2014) T. J. Satchwell et al.   HAEMATOLOGICA

Induction of adult levels of  -globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL

(2014) K. Trakarnsanga et al.   HAEMATOLOGICA

Qualitative and Quantitative Comparison of the Proteome of Erythroid Cells Differentiated from Human iPSCs and Adult Erythroid Cells by Multiplex TMT Labelling and NanoLC-MS/MS

(2014) Kongtana Trakarnsanga et al.   PLoS One

Large-scale production of red blood cells from stem cells: What are the technical challenges ahead?

(2013) Guillaume F. Rousseau et al.   Biotechnology Journal

Isolation and functional characterization of human erythroblasts at distinct stages: implications for understanding of normal and disordered erythropoiesis in vivo

(2013) J. Hu et al.   BLOOD

Extensive Ex Vivo Expansion of Functional Human Erythroid Precursors Established From Umbilical Cord Blood Cells by Defined Factors

(2013) Xiaosong Huang et al.   MOLECULAR THERAPY

Establishment of Immortalized Human Erythroid Progenitor Cell Lines Able to Produce Enucleated Red Blood Cells

(2013) Ryo Kurita et al.   PLoS One

Significant Biochemical, Biophysical and Metabolic Diversity in Circulating Human Cord Blood Reticulocytes

(2013) Benoît Malleret et al.   PLoS One

Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells

(2013) Sho-ichi Hirose et al.   Stem Cell Reports

Maturing reticulocytes internalize plasma membrane in glycophorin A-containing vesicles that fuse with autophagosomes before exocytosis

(2012) R. E. Griffiths et al.   BLOOD

Signaling and cytoskeletal requirements in erythroblast enucleation

(2012) D. G. Konstantinidis et al.   BLOOD

Ex-vivo generation of human red cells for transfusion

(2012) David J. Anstee et al.   CURRENT OPINION IN HEMATOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Manufactured RBC — Rivers of blood, or an oasis in the desert?

(2011) N.E. Timmins et al.   BIOTECHNOLOGY ADVANCES

Proof of principle for transfusion of in vitro-generated red blood cells

(2011) M.-C. Giarratana et al.   BLOOD

Enucleation of human erythroblasts involves non-muscle myosin IIB

(2011) K. Ubukawa et al.   BLOOD

Normal and disordered reticulocyte maturation

(2011) Paul A Ney   CURRENT OPINION IN HEMATOLOGY

Generation of Red Blood Cells from Human Induced Pluripotent Stem Cells

(2011) Jessica Dias et al.   STEM CELLS AND DEVELOPMENT

Ultra-High-Yield Manufacture of Red Blood Cells from Hematopoietic Stem Cells

(2011) Nicholas E. Timmins et al.   TISSUE ENGINEERING PART C-METHODS

Investigating the key membrane protein changes during in vitro erythropoiesis of protein 4.2 (-) cells (mutations Chartres 1 and 2)

(2010) E. van den Akker et al.   HAEMATOLOGICA

Ex vivo large-scale generation of human red blood cells from cord blood CD34+ cells by co-culturing with macrophages

(2008) Akihito Fujimi et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2

(2008) Peng Ji et al.   NATURE CELL BIOLOGY