Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence

(2016) A. Galloway et al.   SCIENCE

ATM deficiency promotes development of murine B-cell lymphomas that resemble diffuse large B-cell lymphoma in humans

(2015) K. S. Hathcock et al.   BLOOD

Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice

(2015) K Yamamoto et al.   LEUKEMIA

The RNA-binding protein HuR is essential for the B cell antibody response

(2015) Manuel D Diaz-Muñoz et al.   NATURE IMMUNOLOGY

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

(2015) Wei Shi et al.   NATURE IMMUNOLOGY

Deletion of AU-Rich Elements within the Bcl2 3′UTR Reduces Protein Expression and B Cell Survival In Vivo

(2015) Manuel D. Díaz-Muñoz et al.   PLoS One

Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression

(2015) Jorge Boucas et al.   PLoS One

Aberrant V(D)J Recombination in Ataxia Telangiectasia Mutated-Deficient Lymphocytes Is Dependent on Nonhomologous DNA End Joining

(2014) A. L. Bredemeyer et al.   JOURNAL OF IMMUNOLOGY

HDMX Folds the Nascent p53 mRNA following Activation by the ATM Kinase

(2014) Laurence Malbert-Colas et al.   MOLECULAR CELL

Post-transcriptional RNA regulons affecting cell cycle and proliferation

(2014) Jeff G. Blackinton et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cyclin B1 mRNA translation is temporally controlled through formation and disassembly of RNA granules

(2013) Tomoya Kotani et al.   JOURNAL OF CELL BIOLOGY

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential Programming of B Cells in AID Deficient Mice

(2013) Marc A. Hogenbirk et al.   PLoS One

Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas

(2013) M. Gostissa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leucine-tRNA Initiates at CUG Start Codons for Protein Synthesis and Presentation by MHC Class I

(2012) S. R. Starck et al.   SCIENCE

The p53 network: cellular and systemic DNA damage responses in aging and cancer

(2012) H. Christian Reinhardt et al.   TRENDS IN GENETICS

Posttranscriptional regulation of gene expression—adding another layer of complexity to the DNA damage response

(2012) Jorge Boucas et al.   Frontiers in Genetics

Effect of mutations on the p53 IRES RNA structure: Implications for de-regulation of the synthesis of p53 isoforms

(2011) Richa Grover et al.   RNA Biology

5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage

(2010) J. Chen et al.   GENES & DEVELOPMENT

p53 Represses Class Switch Recombination to IgG2a through Its Antioxidant Function

(2010) J. E. J. Guikema et al.   JOURNAL OF IMMUNOLOGY

AID-Induced Genotoxic Stress Promotes B Cell Differentiation in the Germinal Center via ATM and LKB1 Signaling

(2010) Mara H. Sherman et al.   MOLECULAR CELL

DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization

(2010) H. Christian Reinhardt et al.   MOLECULAR CELL

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

(2010) Julian König et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

iCLIP Predicts the Dual Splicing Effects of TIA-RNA Interactions

(2010) Zhen Wang et al.   PLOS BIOLOGY

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Oxidative Stress Increases the Number of Stress Granules in Senescent Cells and Triggers a Rapid Decrease in p21waf1/cip1Translation

(2009) Xian Jin Lian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unravelling the ultrastructure of stress granules and associated P-bodies in human cells

(2009) S. Souquere et al.   JOURNAL OF CELL SCIENCE

RNA granules: post-transcriptional and epigenetic modulators of gene expression

(2009) Paul Anderson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis

(2009) G. K. Mahowald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism and Regulation of Class Switch Recombination

(2008) Janet Stavnezer et al.   Annual Review of Immunology

DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

(2008) Andrea L. Bredemeyer et al.   NATURE

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Complementary functions of ATM and H2AX in development and suppression of genomic instability

(2008) S. Zha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Re-programming of translation following cell stress allows IRES-mediated translation to predominate

(2007) Keith A. Spriggs et al.   BIOLOGY OF THE CELL