Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis

Cooperative Effects of Matrix Stiffness and Fluid Shear Stress on Endothelial Cell Behavior

(2015) Julie C. Kohn et al.   BIOPHYSICAL JOURNAL

Immobilized surfactant-nanotube complexes support selectin-mediated capture of viable circulating tumor cells in the absence of capture antibodies

(2015) Michael J. Mitchell et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Targeting the extrinsic apoptotic pathway in cancer: lessons learned and future directions

(2015) Avi Ashkenazi   JOURNAL OF CLINICAL INVESTIGATION

Hetero-modification of TRAIL trimer for improved drug delivery and in vivo antitumor activities

(2015) Li-Qiang Pan et al.   Scientific Reports

Piperlongumine and immune cytokine TRAIL synergize to promote tumor death

(2015) Jiahe Li et al.   Scientific Reports

Human Serum Albumin-TRAIL Conjugate for the Treatment of Rheumatoid Arthritis

(2014) Hyeong Jun Byeon et al.   BIOCONJUGATE CHEMISTRY

Fluid Shear Stress Increases Neutrophil Activation via Platelet-Activating Factor

(2014) Michael J. Mitchell et al.   BIOPHYSICAL JOURNAL

sTRAIL coupled to liposomes improves its pharmacokinetic profile and overcomes neuroblastoma tumour resistance in combination with Bortezomib

(2014) M. Loi et al.   JOURNAL OF CONTROLLED RELEASE

TRAIL-coated leukocytes that kill cancer cells in the circulation

(2014) M. J. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physical Biology in Cancer. 3. The role of cell glycocalyx in vascular transport of circulating tumor cells

(2013) Michael J. Mitchell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Fluid shear stress sensitizes cancer cells to receptor-mediated apoptosis via trimeric death receptors

(2013) Michael J Mitchell et al.   NEW JOURNAL OF PHYSICS

Computational and Experimental Models of Cancer Cell Response to Fluid Shear Stress

(2013) Michael J. Mitchell et al.   Frontiers in Oncology

Ultrasensitive detection of toxic cations through changes in the tunnelling current across films of striped nanoparticles

(2012) Eun Seon Cho et al.   NATURE MATERIALS

On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics

(2012) L Y Dimberg et al.   ONCOGENE

Improved biological half-life and anti-tumor activity of TNF-related apoptosis-inducing ligand (TRAIL) using PEG-exposed nanoparticles

(2011) Sung Mook Lim et al.   BIOMATERIALS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Interstitial flow influences direction of tumor cell migration through competing mechanisms

(2011) W. J. Polacheck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artificial Control of Cell Signaling and Growth by Magnetic Nanoparticles

(2010) Jae-Hyun Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ursolic Acid, a Pentacyclin Triterpene, Potentiates TRAIL-induced Apoptosis through p53-independent Up-regulation of Death Receptors

(2010) Sahdeo Prasad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New insights into apoptosis signaling by Apo2L/TRAIL

(2010) F Gonzalvez et al.   ONCOGENE

Resveratrol Enhances Antitumor Activity of TRAIL in Prostate Cancer Xenografts through Activation of FOXO Transcription Factor

(2010) Suthakar Ganapathy et al.   PLoS One

Engineering Substrate Topography at the Micro- and Nanoscale to Control Cell Function

(2009) Christopher J. Bettinger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A synthetic strategy for mimicking the extracellular matrix provides new insight about tumor cell migration

(2009) Michael P. Schwartz et al.   Integrative Biology

Remote Optical Switch for Localized and Selective Control of Gene Interference

(2009) Somin Eunice Lee et al.   NANO LETTERS

A Balance of Substrate Mechanics and Matrix Chemistry Regulates Endothelial Cell Network Assembly

(2008) Joseph P. Califano et al.   Cellular and Molecular Bioengineering

In vivo investigation of tolerance and antitumor activity of cisplatin-loaded PLGA-mPEG nanoparticles

(2008) George Mattheolabakis et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

To kill a tumor cell: the potential of proapoptotic receptor agonists

(2008) Avi Ashkenazi et al.   JOURNAL OF CLINICAL INVESTIGATION

Ligand-Based Targeting of Apoptosis in Cancer: The Potential of Recombinant Human Apoptosis Ligand 2/Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (rhApo2L/TRAIL)

(2008) Avi Ashkenazi et al.   JOURNAL OF CLINICAL ONCOLOGY

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY