4.3 Review

Review article: The pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment

期刊

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
卷 71, 期 7, 页码 773-799

出版社

SPRINGER HEIDELBERG
DOI: 10.1007/s00228-015-1862-7

关键词

Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; Immunomodulators; Biologics

资金

  1. MSD

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Background The following review is a compilation of the recent advances and knowledge on the behaviour of the most frequently used compounds to treat inflammatory bowel disease in an organism. Results It considers clinical aspects of each entity and the pharmacokinetic/pharmacodynamic relationship supported by the use of plasma monitoring, tissue concentrations, and certain aspects derived from pharmacogenetics.

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