ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation

Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis

(2016) Jennifer L. Larson-Casey et al.   IMMUNITY

EGFR regulates macrophage activation and function in bacterial infection

(2016) Dana M. Hardbower et al.   JOURNAL OF CLINICAL INVESTIGATION

Preventing High Fat Diet-induced Obesity and Improving Insulin Sensitivity through Neuregulin 4 Gene Transfer

(2016) Yongjie Ma et al.   Scientific Reports

Tumor Necrosis Factor Receptor 2 Restricts the Pathogenicity of CD8+ T Cells in Mice With Colitis

(2015) Shivesh Punit et al.   GASTROENTEROLOGY

Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral Nutrition

(2015) Yongjia Feng et al.   MOLECULAR AND CELLULAR BIOLOGY

Intestinal CD169+ macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

(2015) Kenichi Asano et al.   Nature Communications

The ErbB4 Ligand Neuregulin-4 Protects against Experimental Necrotizing Enterocolitis

(2014) Steven J. McElroy et al.   AMERICAN JOURNAL OF PATHOLOGY

Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages

(2014) Yasutaka Okabe et al.   CELL

Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization

(2014) Yuli Lin et al.   Cellular & Molecular Immunology

Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

(2014) Dror S. Shouval et al.   IMMUNITY

Macrophage-Restricted Interleukin-10 Receptor Deficiency, but Not IL-10 Deficiency, Causes Severe Spontaneous Colitis

(2014) Ehud Zigmond et al.   IMMUNITY

Activation of the Epidermal Growth Factor Receptor in Macrophages Regulates Cytokine Production and Experimental Colitis

(2014) N. Lu et al.   JOURNAL OF IMMUNOLOGY

The brown fat–enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis

(2014) Guo-Xiao Wang et al.   NATURE MEDICINE

Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages

(2014) Guang Sheng Ling et al.   Nature Communications

Refinement in Localization and Identification of Gene Regions Associated with Crohn Disease

(2012) Heather Elding et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Neuregulin-4 Is a Survival Factor for Colon Epithelial Cells both in Culture andin Vivo

(2012) Jessica K. Bernard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes

(2012) Justine Bacchetta et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Epidermal growth factor receptor inhibits colitis-associated cancer in mice

(2012) Philip E. Dubé et al.   JOURNAL OF CLINICAL INVESTIGATION

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

(2012) A. Arranz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidermal growth factor/TNF-α transactivation modulates epithelial cell proliferation and apoptosis in a mouse model of parenteral nutrition

(2011) Yongjia Feng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Function ofERBB4is determined by alternative splicing

(2011) Ville Veikkolainen et al.   CELL CYCLE

Engineered Bivalent Ligands to Bias ErbB Receptor-mediated Signaling and Phenotypes

(2011) Steven M. Jay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

(2011) Oscar Medina-Contreras et al.   JOURNAL OF CLINICAL INVESTIGATION

IGF-1 increases macrophage motility via PKC/p38-dependent αvβ3-integrin inside-out signaling

(2010) Vesna Furundzija et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In Vitro-Derived Alternatively Activated Macrophages Reduce Colonic Inflammation in Mice

(2010) Meaghan M. Hunter et al.   GASTROENTEROLOGY

Downregulation of serum epidermal growth factor in patients with inflammatory bowel disease. Is there a link with mucosal damage?

(2010) Konstantinos A. Oikonomou et al.   GROWTH FACTORS

Reduced thymic expression of ErbB receptors without auto-antibodies against synaptic ErbB in myasthenia gravis

(2010) Kathleen Vrolix et al.   JOURNAL OF NEUROIMMUNOLOGY

Cell Death or Survival Promoted by Alternative Isoforms of ErbB4

(2010) Maria Sundvall et al.   MOLECULAR BIOLOGY OF THE CELL

Preventive Effects of Heregulin-β 1 on Macrophage Foam Cell Formation and Atherosclerosis

(2009) Gang Xu et al.   CIRCULATION RESEARCH

Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium

(2009) Daekee Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

The ErbB4 Growth Factor Receptor Is Required for Colon Epithelial Cell Survival in the Presence of TNF

(2008) Mark R. Frey et al.   GASTROENTEROLOGY