ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line

Reactive oxygen species and cancer paradox: To promote or to suppress?

(2017) Sehamuddin Galadari et al.   FREE RADICAL BIOLOGY AND MEDICINE

Daphnetin-mediated Nrf2 antioxidant signaling pathways ameliorate tert-butyl hydroperoxide ( t -BHP)-induced mitochondrial dysfunction and cell death

(2017) Hongming Lv et al.   FREE RADICAL BIOLOGY AND MEDICINE

206 CRISPR/Cas9-MEDIATED REPAIR OF THE NHLRC2 LOCUS IN BEEF CATTLE

(2017) K. M. Polkoff et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion

(2017) Wenwen Zhao et al.   Redox Biology

Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells

(2016) Shuhei Ishikura et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Discovery of Novel Biomarkers for Alzheimer’s Disease from Blood

(2016) Jintao Long et al.   DISEASE MARKERS

The Nuclear Zinc Finger Protein Zfat Maintains FoxO1 Protein Levels in Peripheral T Cells by Regulating the Activities of Autophagy and the Akt Signaling Pathway

(2016) Shuhei Ishikura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ROS homeostasis and metabolism: a dangerous liason in cancer cells

(2016) E Panieri et al.   Cell Death & Disease

Oxidative stress, a new hallmark in the pathophysiology of Lafora progressive myoclonus epilepsy

(2015) Carlos Romá-Mateo et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation

(2015) Inga Loedige et al.   Cell Reports

Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis

(2015) Fabian Treude et al.   Oncotarget

Old, new and emerging functions of caspases

(2014) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation

(2014) I. Loedige et al.   GENES & DEVELOPMENT

Zfat-Deficient CD4+CD8+Double-Positive Thymocytes Are Susceptible to Apoptosis With Deregulated Activation of p38 and JNK

(2014) Shuhei Ishikura et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing

(2014) Dirk Heckl et al.   NATURE BIOTECHNOLOGY

The Effect oftert-Butyl Hydroperoxide-Induced Oxidative Stress on Lean and Steatotic Rat HepatocytesIn Vitro

(2014) Otto Kučera et al.   Oxidative Medicine and Cellular Longevity

Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

(2013) Jacqueline K. White et al.   CELL

Lafora disease: Severe phenotype associated with homozygous deletion of the NHLRC1 gene

(2013) Miljana Kecmanović et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Zfat-Deficiency Results in a Loss of CD3ζ Phosphorylation with Dysregulation of ERK and Egr Activities Leading to Impaired Positive Selection

(2013) Masahiro Ogawa et al.   PLoS One

Caspase Functions in Cell Death and Disease

(2013) D. R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology

Comparative Genomics of Thiol Oxidoreductases Reveals Widespread and Essential Functions of Thiol-based Redox Control of Cellular Processes

(2011) Dmitri E. Fomenko et al.   ANTIOXIDANTS & REDOX SIGNALING

Structure, Function, and Mechanism of Thioredoxin Proteins

(2010) Jean-Francois Collet et al.   ANTIOXIDANTS & REDOX SIGNALING

Cysteine-Based Redox Switches in Enzymes

(2010) Chananat Klomsiri et al.   ANTIOXIDANTS & REDOX SIGNALING

Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells

(2010) Yu-Feng Kuo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selenite induces redox-dependent Bax activation and apoptosis in colorectal cancer cells

(2009) Fang Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thiol-Based Redox Switches in Eukaryotic Proteins

(2008) Nicolas Brandes et al.   ANTIOXIDANTS & REDOX SIGNALING