Neuromodulatory Systems and Their Interactions: A Review of Models, Theories, and Experiments

Nicotine reverses hypofrontality in animal models of addiction and schizophrenia

(2017) Fani Koukouli et al.   NATURE MEDICINE

Reward sensitivity deficits modulated by dopamine are associated with apathy in Parkinson’s disease

(2016) Kinan Muhammed et al.   BRAIN

Hippocampus and Prefrontal Cortex Predict Distinct Timescales of Activation in the Human Ventral Tegmental Area

(2016) Vishnu P. Murty et al.   CEREBRAL CORTEX

Multiplexed neurochemical signaling by neurons of the ventral tegmental area

(2016) David J. Barker et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Anxiety

(2016) Michelle G Craske et al.   LANCET

Dissociable Effects of Serotonin and Dopamine on the Valuation of Harm in Moral Decision Making

(2015) Molly J. Crockett et al.   CURRENT BIOLOGY

An acetylcholine-activated microcircuit drives temporal dynamics of cortical activity

(2015) Naiyan Chen et al.   NATURE NEUROSCIENCE

Disinhibition, a Circuit Mechanism for Associative Learning and Memory

(2015) Johannes J. Letzkus et al.   NEURON

Cortical Membrane Potential Signature of Optimal States for Sensory Signal Detection

(2015) Matthew J. McGinley et al.   NEURON

Reinforcement learning in depression: A review of computational research

(2015) Chong Chen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Improper activation of D1 and D2 receptors leads to excess noise in prefrontal cortex

(2015) Michael C. Avery et al.   Frontiers in Computational Neuroscience

A network model of basal ganglia for understanding the roles of dopamine and serotonin in reward-punishment-risk based decision making

(2015) Pragathi P. Balasubramani et al.   Frontiers in Computational Neuroscience

Clinical and Biochemical Manifestations of Depression: Relation to the Neurobiology of Stress

(2015) Phillip W. Gold et al.   NEURAL PLASTICITY

Neural Substrates of Dopamine D2 Receptor Modulated Executive Functions in the Monkey Prefrontal Cortex

(2014) M. Victoria Puig et al.   CEREBRAL CORTEX

Learning to ignore: A modeling study of a decremental cholinergic pathway and its influence on attention and learning

(2014) N. Oros et al.   LEARNING & MEMORY

Pupil Fluctuations Track Fast Switching of Cortical States during Quiet Wakefulness

(2014) Jacob Reimer et al.   NEURON

Phasic Dopamine Release Drives Rapid Activation of Striatal D2-Receptors

(2014) Pamela F. Marcott et al.   NEURON

Pedunculopontine tegmental nucleus neurons provide reward, sensorimotor, and alerting signals to midbrain dopamine neurons

(2014) S. Hong et al.   NEUROSCIENCE

Sparse and distributed coding of episodic memory in neurons of the human hippocampus

(2014) John T. Wixted et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pupil dilation signals uncertainty and surprise in a learning gambling task

(2014) Claudio Lavín et al.   Frontiers in Behavioral Neuroscience

Serotonin Regulates Performance Nonmonotonically in a Spatial Working Memory Network

(2013) Maria Cano-Colino et al.   CEREBRAL CORTEX

Mechanisms underlying the basal forebrain enhancement of top-down and bottom-up attention

(2013) Michael C. Avery et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A large-scale neural network model of the influence of neuromodulatory levels on working memory and behavior

(2013) Michael C. Avery et al.   Frontiers in Computational Neuroscience

Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions

(2013) Christina M. Gremel et al.   Nature Communications

A neurorobotic platform to test the influence of neuromodulatory signaling on anxious and curious behavior

(2013) Jeffrey L. Krichmar   Frontiers in Neurorobotics

The Computational Anatomy of Psychosis

(2013) Rick A. Adams et al.   Frontiers in Psychiatry

Interactions between the neuromodulatory systems and the amygdala: exploratory survey using the Allen Mouse Brain Atlas

(2012) Andrew Zaldivar et al.   Brain Structure & Function

From prediction error to incentive salience: mesolimbic computation of reward motivation

(2012) Kent C. Berridge   EUROPEAN JOURNAL OF NEUROSCIENCE

Abnormal social reward processing in autism as indexed by pupillary responses to happy faces

(2012) Leigh Sepeta et al.   Journal of Neurodevelopmental Disorders

Serotonin Selectively Modulates Reward Value in Human Decision-Making

(2012) B. Seymour et al.   JOURNAL OF NEUROSCIENCE

Synaptic Activity Unmasks Dopamine D2 Receptor Modulation of a Specific Class of Layer V Pyramidal Neurons in Prefrontal Cortex

(2012) S. Gee et al.   JOURNAL OF NEUROSCIENCE

Rational regulation of learning dynamics by pupil-linked arousal systems

(2012) Matthew R Nassar et al.   NATURE NEUROSCIENCE

Network properties of a computational model of the dorsal raphe nucleus

(2012) KongFatt Wong-Lin et al.   NEURAL NETWORKS

Modulation for emergent networks: Serotonin and dopamine

(2012) Juyang Weng et al.   NEURAL NETWORKS

Dissociating the Cognitive Effects of Levodopa versus Dopamine Agonists in a Neurocomputational Model of Learning in Parkinson’s Disease

(2012) Ahmed A. Moustafa et al.   Neurodegenerative Diseases

Neuromodulation of Thought: Flexibilities and Vulnerabilities in Prefrontal Cortical Network Synapses

(2012) Amy F.T. Arnsten et al.   NEURON

Serotonin Modulates the Effects of Pavlovian Aversive Predictions on Response Vigor

(2012) Molly J Crockett et al.   NEUROPSYCHOPHARMACOLOGY

Serotonin transporter gene, stress and raphe–raphe interactions: a molecular mechanism of depression

(2012) Agnes J. Jasinska et al.   TRENDS IN NEUROSCIENCES

Simulation of cholinergic and noradrenergic modulation of behavior in uncertain environments

(2012) Michael C. Avery et al.   Frontiers in Computational Neuroscience

Reciprocity and Retaliation in Social Games With Adaptive Agents

(2012) D. E. Asher et al.   IEEE Transactions on Autonomous Mental Development

Cholinergic modulation of cognitive processing: insights drawn from computational models

(2012) Ehren L. Newman et al.   Frontiers in Behavioral Neuroscience

Dopamine, Affordance and Active Inference

(2012) Karl J. Friston et al.   PLoS Computational Biology

Cholinergic control of cortical network interactions enables feedback-mediated attentional modulation

(2011) Gustavo Deco et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Activation of Dorsal Raphe Serotonin Neurons Underlies Waiting for Delayed Rewards

(2011) K. Miyazaki et al.   JOURNAL OF NEUROSCIENCE

Control of visual cortical signals by prefrontal dopamine

(2011) Behrad Noudoost et al.   NATURE

Expectancy-related changes in firing of dopamine neurons depend on orbitofrontal cortex

(2011) Yuji K Takahashi et al.   NATURE NEUROSCIENCE

From reinforcement learning models to psychiatric and neurological disorders

(2011) Tiago V Maia et al.   NATURE NEUROSCIENCE

Higher Levels of Glutamate in the Associative-Striatum of Subjects with Prodromal Symptoms of Schizophrenia and Patients with First-Episode Psychosis

(2011) Camilo de la Fuente-Sandoval et al.   NEUROPSYCHOPHARMACOLOGY

Serotonin and dopamine striatal innervation in Parkinson’s disease and Huntington’s chorea

(2011) Catherine Bédard et al.   PARKINSONISM & RELATED DISORDERS

Stress-Related Noradrenergic Activity Prompts Large-Scale Neural Network Reconfiguration

(2011) E. J. Hermans et al.   SCIENCE

Pupil dilation signals surprise: evidence for noradrenaline’s role in decision making

(2011) Kerstin Preuschoff   Frontiers in Neuroscience

A Neurocomputational Model of Dopamine and Prefrontal–Striatal Interactions during Multicue Category Learning by Parkinson Patients

(2010) Ahmed A. Moustafa et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Updating Beliefs for a Decision: Neural Correlates of Uncertainty and Underconfidence

(2010) E. R. Stern et al.   JOURNAL OF NEUROSCIENCE

Dopamine in Motivational Control: Rewarding, Aversive, and Alerting

(2010) Ethan S. Bromberg-Martin et al.   NEURON

Enhancement of Attentional Performance by Selective Stimulation of α4β2* nAChRs: Underlying Cholinergic Mechanisms

(2010) William M Howe et al.   NEUROPSYCHOPHARMACOLOGY

Opponency Revisited: Competition and Cooperation Between Dopamine and Serotonin

(2010) Y-Lan Boureau et al.   NEUROPSYCHOPHARMACOLOGY

Serotonin: Modulator of a drive to withdraw

(2009) Mattie Tops et al.   BRAIN AND COGNITION

Cholinergic optimization of cue-evoked parietal activity during challenged attentional performance

(2009) John I. Broussard et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Serotonin Affects Association of Aversive Outcomes to Past Actions

(2009) S. C. Tanaka et al.   JOURNAL OF NEUROSCIENCE

Reconciling the Role of Serotonin in Behavioral Inhibition and Aversion: Acute Tryptophan Depletion Abolishes Punishment-Induced Inhibition in Humans

(2009) M. J. Crockett et al.   JOURNAL OF NEUROSCIENCE

Basal forebrain activation enhances cortical coding of natural scenes

(2009) Michael Goard et al.   NATURE NEUROSCIENCE

A new perspective on the role of the orbitofrontal cortex in adaptive behaviour

(2009) Geoffrey Schoenbaum et al.   NATURE REVIEWS NEUROSCIENCE

Stress signalling pathways that impair prefrontal cortex structure and function

(2009) Amy F. T. Arnsten   NATURE REVIEWS NEUROSCIENCE

Freedom of movement and the stability of its unfolding in free exploration of mice

(2009) Ehud Fonio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Neuromodulatory System: A Framework for Survival and Adaptive Behavior in a Challenging World

(2008) Jeffrey L. Krichmar   ADAPTIVE BEHAVIOR

Cholinergic Mediation of Attention

(2008) Vinay Parikh et al.   Annals of the New York Academy of Sciences

The Dual-State Theory of Prefrontal Cortex Dopamine Function with Relevance to Catechol-O-Methyltransferase Genotypes and Schizophrenia

(2008) Daniel Durstewitz et al.   BIOLOGICAL PSYCHIATRY

Low-Serotonin Levels Increase Delayed Reward Discounting in Humans

(2008) N. Schweighofer et al.   JOURNAL OF NEUROSCIENCE

Reward-Dependent Modulation of Neuronal Activity in the Primate Dorsal Raphe Nucleus

(2008) K. Nakamura et al.   JOURNAL OF NEUROSCIENCE

Acetylcholine contributes through muscarinic receptors to attentional modulation in V1

(2008) J. L. Herrero et al.   NATURE

Modulators of decision making

(2008) Kenji Doya   NATURE NEUROSCIENCE

Computational models of schizophrenia and dopamine modulation in the prefrontal cortex

(2008) Edmund T. Rolls et al.   NATURE REVIEWS NEUROSCIENCE

The Reorienting System of the Human Brain: From Environment to Theory of Mind

(2008) Maurizio Corbetta et al.   NEURON

Serotonin Modulates Behavioral Reactions to Unfairness

(2008) M. J. Crockett et al.   SCIENCE

Serotoninergic regulation of emotional and behavioural control processes

(2007) Roshan Cools et al.   TRENDS IN COGNITIVE SCIENCES