Neuroprotective Mechanisms of Lycium barbarum Polysaccharides Against Ischemic Insults by Regulating NR2B and NR2A Containing NMDA Receptor Signaling Pathways

Structure characterization, chemical and enzymatic degradation, and chain conformation of an acidic polysaccharide from Lycium barbarum L.

(2016) Wei Liu et al.   CARBOHYDRATE POLYMERS

Structure identification of a polysaccharide purified from Lycium barbarium fruit

(2016) Yunfei Yuan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Neuro-protective Mechanisms of Lycium barbarum

(2016) Xiwen Xing et al.   NEUROMOLECULAR MEDICINE

Changes in synaptic plasticity and expression of glutamate receptor subunits in the CA1 and CA3 areas of the hippocampus after transient global ischemia

(2016) Xin-Jia Han et al.   NEUROSCIENCE

Chronic Cerebral Hypoperfusion Induces Vascular Plasticity and Hemodynamics but Also Neuronal Degeneration and Cognitive Impairment

(2015) Zhen Jing et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Structural characterization of LbGp1 from the fruits of Lycium barbarum L.

(2014) Zhongfu Wang et al.   FOOD CHEMISTRY

Lycium barbarum Polysaccharide Prevents Focal Cerebral Ischemic Injury by Inhibiting Neuronal Apoptosis in Mice

(2014) Tengfei Wang et al.   PLoS One

Treatment of D-galactose induced mouse aging with Lycium barbarum polysaccharides and its mechanism study

(2013) T Tang et al.   African Journal of Traditional Complementary and Alternative Medicines

Characterization and hypoglycemic effect of a polysaccharide extracted from the fruit of Lycium barbarum L.

(2013) Jing Zhu et al.   CARBOHYDRATE POLYMERS

Triheteromeric NMDA Receptors at Hippocampal Synapses

(2013) K. R. Tovar et al.   JOURNAL OF NEUROSCIENCE

Lycium Barbarum (Wolfberry) Reduces Secondary Degeneration and Oxidative Stress, and Inhibits JNK Pathway in Retina after Partial Optic Nerve Transection

(2013) Hongying Li et al.   PLoS One

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Protective effects of Lycium barbarum polysaccharide on neonatal rat primary cultured hippocampal neurons injured by oxygen-glucose deprivation and reperfusion

(2012) Chen Rui et al.   JOURNAL OF MOLECULAR HISTOLOGY

nNOS mediated mitochondrial injury in LPS stimulated oligodendrocytes

(2012) S.-Y. Yao et al.   MITOCHONDRION

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

(2012) Douglas J. Cook et al.   NATURE

Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy

(2012) Naoki Ito et al.   NATURE MEDICINE

Lycium barbarum Extracts Protect the Brain from Blood-Brain Barrier Disruption and Cerebral Edema in Experimental Stroke

(2012) Di Yang et al.   PLoS One

Protection of Retinal Ganglion Cells and Retinal Vasculature by Lycium Barbarum Polysaccharides in a Mouse Model of Acute Ocular Hypertension

(2012) Xue-Song Mi et al.   PLoS One

Molecular basis of NMDA receptor functional diversity

(2011) Pierre Paoletti   EUROPEAN JOURNAL OF NEUROSCIENCE

Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation

(2011) Jia Xiao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function

(2011) Clare M. Gladding et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Lycium Barbarum Polysaccharides Reduce Neuronal Damage, Blood-Retinal Barrier Disruption and Oxidative Stress in Retinal Ischemia/Reperfusion Injury

(2011) Suk-Yee Li et al.   PLoS One

Structure characterization and hypoglycemic activity of a polysaccharide isolated from the fruit of Lycium barbarum L.

(2010) Shan Zou et al.   CARBOHYDRATE POLYMERS

Neu2000, an NR2B-selective, moderate NMDA receptor antagonist and potent spin trapping molecule for stroke

(2010) S.J. Cho et al.   DRUG NEWS & PERSPECTIVES

Alleviation of the acute doxorubicin-induced cardiotoxicity by Lycium barbarum polysaccharides through the suppression of oxidative stress

(2010) Yan-Fei Xin et al.   FOOD AND CHEMICAL TOXICOLOGY

Chemical characterization of lycium barbarum polysaccharides and its inhibition against liver oxidative injury of high-fat mice

(2010) Hua-Tao Wu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95

(2010) Li Zhou et al.   NATURE MEDICINE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Calcitonin gene-related peptide enhances CREB phosphorylation and attenuates tau protein phosphorylation in rat brain during focal cerebral ischemia/reperfusion

(2009) Zheng-Hong Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Polysaccharides from Wolfberry Antagonizes Glutamate Excitotoxicity in Rat Cortical Neurons

(2009) Yuen-Shan Ho et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Chromatographic determination of polysaccharides in Lycium barbarum Linnaeus

(2009) Chia Chi Wang et al.   FOOD CHEMISTRY

Antioxidative activity of polysaccharide fractions isolated from Lycium barbarum Linnaeus

(2009) C.L. Lin et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Pretreatment with a single estradiol-17β bolus activates cyclic-AMP response element binding protein and protects CA1 neurons against global cerebral ischemia

(2009) A.P. Raval et al.   NEUROSCIENCE

Lycium barbarum (goji) juice improves in vivo antioxidant biomarkers in serum of healthy adults

(2009) Harunobu Amagase et al.   NUTRITION RESEARCH

Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors

(2008) F. Léveillé et al.   FASEB JOURNAL

Differential Roles of NMDA Receptor Subtypes in Ischemic Neuronal Cell Death and Ischemic Tolerance

(2008) Min Chen et al.   STROKE